Search results for "15"
showing 10 items of 8669 documents
Des « petits » vignobles en émergence en Bourgogne : éléments d’une dynamique en cours
2015
International audience; La dynamique récente des petits vignobles de l’Yonne, de la Côte-d’Or et peut-être de la Saône et Loire illustre en tout cas une fois de plus le modèle de développement et la pérennité des vignobles de qualité de R. Dion fondé sur le détachement de l’orbite des villes et des voies du commerce facile (comme ce fut le cas pour la Côte-d’Or). Cependant dans le cas présent, il s’agit d’un modèle inversé où le rapprochement des élites urbaines favorise aujourd’hui au contraire les nouveaux vignobles de qualité péri-urbains, les vignobles de l’Yonne bénéficiant de cet effet en raison du rapprochement facilité par les voies de communication, le tourisme vert et patrimonial …
Evoluzione dei composti volatili nel processo di distillazione delle vinacce di Grillo
2011
composti volatili, Grillo, vinacce, distillato
Tecnica dell'acidificazione dei vini
2008
Produzione di vini bianchi senza l’uso di solfiti
2014
Esperienze di vinificazione di varietà autoctone siciliane con protezione del mosto dalle ossidazioni
2008
Suffering, Surviving and Coping : Experiences of Violence and Defeat in Post-War Europe
2017
Korruptio ja huono hallinto tutkimuskohteena varhaismodernissa Ruotsissa : näkökulmat, menetelmät ja mahdollisuudet
2021
Artikkelissa käsitellään korruption ja huonon hallinnon tutkimusta menneisyydessä, ennen kaikkea Ruotsin ja Suomen yhteisen historian ajalla. Tarkoituksena on antaa tämänhetkisen tutkimustiedon valossa yleiskuva siitä, mitä teemasta tällä hetkellä tiedetään sekä pohtia tulevan tutkimuksen mahdollisuuksia, ongelmia (mukaan luettuna lähdekriittiset vaikeudet) sekä vastaisen tutkimuksen lähestymistapoja.
Immune responses during COVID-19 infection
2020
International audience; Over the past 16 years, three coronaviruses (CoVs), severe acute respiratory syndrome CoV (SARS-CoV) in 2002, Middle East respiratory syndrome CoV (MERS-CoV) in 2012 and 2015, and SARS-CoV-2 in 2020, have been causing severe and fatal human epidemics. The unpredictability of coronavirus disease-19 (COVID-19) poses a major burden on health care and economic systems across the world. This is caused by the paucity of in-depth knowledge of the risk factors for severe COVID-19, insufficient diagnostic tools for the detection of SARS-CoV-2, as well as the absence of specific and effective drug treatments. While protective humoral and cellular immune responses are usually m…
SARS-CoV-2 envelope protein topology in eukaryotic membranes
2020
Coronavirus E protein is a small membrane protein found in the virus envelope. Different coronavirus E proteins share striking biochemical and functional similarities, but sequence conservation is limited. In this report, we studied the E protein topology from the new SARS-CoV-2 virus both in microsomal membranes and in mammalian cells. Experimental data reveal that E protein is a single-spanning membrane protein with the N-terminus being translocated across the membrane, while the C-terminus is exposed to the cytoplasmic side (Nt lum /Ct cyt ). The defined membrane protein topology of SARS-CoV-2 E protein may provide a useful framework to understand its interaction with other viral and ho…
Antiviral prophylaxis in patients with haematological malignancies and solid tumours: Guidelines of the Infectious Diseases Working Party (AGIHO) of …
2006
Morbidity and mortality in patients with malignancies are increased by viral infections. These mostly are reactivations of asymptomatic latent infections. They primarily concern clinical entities associated with the reactivation of herpes viruses, such as varicella zoster virus (VZV) and cytomegalovirus (CMV). Respiratory tract infections caused by influenza, parainfluenza or respiratory syncytial virus (RSV) are less common. Since reactivation of latent infections has major clinical impact, antiviral prophylaxis is an attractive approach for patients expecting immunosuppression. The main risk factor for clinically relevant reactivation is profound disruption of cellular immune response. Du…