Search results for "16"

Oxidative stress induces myeloperoxidase expression in endocardial endothelial cells from patients with chronic heart failure.

2009

Increased oxidative stress has been implicated in the pathogenesis of a number of cardiovascular diseases. Recent findings suggest that myeloperoxidase (MPO) may play a key role in the initiation and maintenance of chronic heart failure (CHF) by contributing to the depletion of the intracellular reservoir of nitric oxide (NO). NO consumption through MPO activity may lead to protein chlorination or nitration, leading to tissue damage. Primary cultures of human endocardial endothelial cells (EEC) obtained at heart transplantation of patients with CHF and human umbilical vein endothelial cells (HUVEC) were subjected to oxidative stress by incubation with hydrogen peroxide at non lethal (60 mic…

Time trends, sociodemographic and health factors associated with discharge and length of stay of hospitalised patients with sickle cell disease in Gh…

2021

ObjectivePatients with sickle cell disease (SCD) are prone to multiple episodes resulting in frequent hospital visits. We determined the time trends, sociodemographic and health factors associated with length of stay (LoS) for patients with SCD in Ghana.Design, participants, settingWe retrospectively analysed SCD hospitalisation records of 22 680 patients from a nationwide database of the Ghana Health Service from 2012 to 2017.Outcome measuresFactors associated with LoS were estimated using Cox regression, while the cumulative incidence of being discharged alive was estimated with in-hospital death as a competing risk.ResultsPatients admitted for SCD over 6 years constituted 22 680 (0.8%) o…

[Adverse reactions to human papillomavirus vaccine in the Valencian Community (2007-2011)].

2014

Introduction: In 2009, two cases of seizures in adolescents following quadrivalent human papillomavirus vaccine (qHPV) administration generated important media attention, and adversely affected public trust in this vaccine. Our objectives were to describe suspected adverse reactions (SARs) reported to the Pharmacovigilance Centre in the Valencian Community (PCVC) after administration of HPV vaccine, and to compare reporting rates of syncope and seizures following this vaccine with those of other vaccines administered to girls aged 13–15 years. Materials and methods: Descriptive study of SARs reported following administration of this vaccine to the PCVC between 2007 and 2011. Results: The cl…

The effect of the cluster randomized HIPPA intervention on childcare children’s overall physical activity

2017

Background The effect of the cluster randomized Home- and childcare-based Intervention to Promote Physical Activity (HIPPA) intervention on the everyday physical activity (PA) of children between the ages of 4 to 5 years was evaluated. Material/Methods Fourteen childcare centers with 102 children born in 2007 and their families participated in the study. HIPPA was implemented over a single preschool year in seven childcare centers while seven other centers continued their normal care (control group, CG). The PA levels of children were assessed by accelerometers six times every six months during two and a half years of research. Valid PA data were obtained from 69 children at baseline and an…

The story models of physiotherapy students’ professional development. Narrative research

2014

The aim of this article is to investigate students’ narratives about their professional development process. This research brings new kind of knowledge to continuing learning, developing education and planning the curriculum in physiotherapy education. The European Qualification Framework (EQF) defines learning competences in education; qualitative research has a narrative approach. The material consists of eight voluntarily participating physiotherapy students’ portfolios written during their whole study time. The longitudinal data describes them as learners and their development process. The major findings are four main episodes in professional development: the previous studies, a new way…

Implementation of a strategy involving a multidisciplinary mobile unit team to prevent hospital admission in nursing home residents: protocol of a qu…

2020

IntroductionNursing home residents represent a particularly vulnerable population experiencing high risk of unplanned hospital admissions, but few interventions have proved effective in reducing this risk. The aim of this research will be to verify the effects of a hospital-based multidisciplinary mobile unit (MMU) team intervention delivering urgent care to nursing home residents directly at their bedside.Methods and analysisFour nursing homes based in the Parma province, in Northern Italy, will be involved in this prospective, pragmatic, multicentre, 18-month quasiexperimental study (sequential design with two cohorts). The residents of two nursing homes will receive the MMU team care int…

Public health nurses’ concerns in preschool-aged children’s health check-ups

2015

The aim is to describe Finnish public health nurses’ concerns during regular health check-ups of preschool-aged children. In 2011, focus-group interviews were conducted with 12 public health nurses. The data were analysed using inductive content analysis. Public health nurses’ concerns dealt with the healthy growth and development of children and their ability to cope with difficult family situations, as well as the everyday reality of parenting. The concerns of public health nurses related to children’s health focused on their psychosocial development. Concerns also focused on the interaction between mother and baby, children’s behavioural problems and their cognitive development, parents…

Effects of Sulpiride Treatment on the Hypothalamic Supraoptic and Paraventricular Nuclei

2009

Insights on Central and Peripheral Venous Catheterization; Biology, Anatomy, Surgical Aspects and Nursing Management (Our Experience)

2009

After a review of the main anatomical districts of relevance to central and peripheral venous catheterization, we analyze the primary guidelines for the management of cannulation of central and peripheral venous catheters; a background study relative to this subject is then carried out. The aim of the present study is to review the main central and peripheral catheterization methods, and to share our experience with particular emphasis on analyzing common complications

The new criteria for classification of rheumatoid arthritis: what we need to know for clinical practice.

2011

The new criteria for classification of Rheumatoid Arthritis have been recently released. They incorporate the anti-Citrullinated Protein antibody testing and the other classic criteria in a score system (the diagnosis of definite rheumatoid arthritis is made by a total score ≥6). These criteria try to meet the pressing needs to gain sensitivity in early disease. Symptoms, elevated acute-phase response, serologic abnormality, joint involvement were all considered for scoring after confirming the presence of synovitis in at least 1 joint in the absence of an alternative diagnosis that better explains the synovitis. However, no sensitivity and specificity has been showed. Moreover, Area Under …