Search results for "17"
showing 10 items of 14048 documents
Reescritura de las fuentes y sustituciones léxicas en el De Proprietate Animalium de Manuel Files: ¿variación estilística o cambio de nivel lingüísti…
2020
El De Proprietate Animalium de Manuel Files es un poema didáctico del s. XIV que parafrasea libremente varias fuentes literarias de contenido zoológico, entre las que destaca la Historia Animalium de Claudio Eliano. Un análisis detallado de los procedimientos de sustitución léxica realizado por el autor, apoyado en la consulta de los diccionarios bizantinos, permite reconocer su originalidad compositiva, la riqueza expresiva de su vocabulario poético, pero también la clara conciencia de la existencia de diferentes niveles de lengua y de los muy diversos registros utilizados por el autor.
Induction of body weight loss through RNAi-knockdown of APOBEC1 gene expression in transgenic rabbits
2014
In the search of new strategies to fight against obesity, we targeted a gene pathway involved in energy uptake. We have thus investigated the APOB mRNA editing protein (APOBEC1) gene pathway that is involved in fat absorption in the intestine. The APOB gene encodes two proteins, APOB100 and APOB48, via the editing of a single nucleotide in the APOB mRNA by the APOBEC1 enzyme. The APOB48 protein is mandatory for the synthesis of chylomicrons by intestinal cells to transport dietary lipids and cholesterol. We produced transgenic rabbits expressing permanently and ubiquitously a small hairpin RNA targeting the rabbit APOBEC1 mRNA. These rabbits exhibited a moderately but significantly reduced …
Can Oscillatory Alpha-Gamma Phase-Amplitude Coupling be Used to Understand and Enhance TMS Effects?
2019
Recent applications of simultaneous scalp electroencephalography (EEG) and transcranial magnetic stimulation (TMS) suggest that adapting stimulation to underlying brain states may enhance neuroplastic effects of TMS. It is often assumed that longer-lasting effects of TMS on brain function may be mediated by phasic interactions between TMS pulses and endogenous cortical oscillatory dynamics. The mechanisms by which TMS exerts its neuromodulatory effects, however, remain unknown. Here, we discuss evidence concerning the functional effects on synaptic plasticity of oscillatory cross-frequency coupling in cortical networks as a potential framework for understanding the neuromodulatory effects o…
THE SCENOGRAPHY OF SERPOTTA STUCCOES REVISITED - MATERIAL AND FORM
2015
The material that lies beneath the smooth shining surface of the stuccoes of the Serpotta family who used to work in Sicily from 1670 to 1730, has been thoroughly studied in previous papers, disclosing the deep, albeit empirical, knowledge of materials science that guided the artists in creating their masterpieces. In this work, attention is focused on the solid perspective and on the scenographic sculpture by Giacomo Serpotta, who is acknowledged as the leading exponent of the School. The study deals with some particular works of the artist, the “small-scaled plastic theatres”, so-called “teatrini”, which he made for the San Lorenzo Oratory in Palermo. On the basis of archival documents an…
AR to Rediscover Heritage: the Case Study of Salerno Defense System
2022
Recognizing and transmitting the uniqueness and identity of one’s territory represents fundamental step to guarantee its sustainability, protection and valorisation. Of particular importance, moreover, is the issues of the lesser-known heritage of great value but which, unfortunately, in some cases is still little known and often in a state of neglect. However, the diffusion of new technology and the great development of digitization positively contribute to the accessibility and visibility of these patrimonies, increasing the knowledge and the dissemination. This contribution focuses on one of the towers of the coastal defence system, a perfect example of a lesser-known architecture of gre…
Tecniche di rilevamento architettonico: innovazione e integrazione
2008
In particolare si pone l’attenzione sulle problematiche della conservazione e del restauro dell’architettura dei primi decenni del ‘900 con nuove tecnologie, approfondendo alcune tipologie e problematiche di degrado più presenti sul materiale. Si propone un caso specifico di intervento su un edificio storico al fine di valutarne lo stato di salute e la durabilità del conglomerato cementizio armato tradizionale operando dei confronti con i nuovi calcestruzzi. Documentando con schede di rilievo tipologico-funzionale e tecnologico e con quadri fessurativi, si presentano i primi risultati delle indagini e delle prove distruttive e non-distruttive su alcune parti più rappresentative delle divers…
Metodologie di rilievo metrico e diagnosi materica in edifici storici. Casi studio.
2010
Ancora oggi manca una codificazione di regole da suggerire perché vengano seguite con puntualità per ripristinare e per risanare i monumenti e gli edifici di interesse storico risalenti ai primi anni del secolo scorso, realizzati in calcestruzzo o contenenti parti ornamentali ma anche funzionali in calcestruzzo. E’ prevalsa l’abitudine di trattare questi ultimi come se fossero costruiti secondo le regole dell’odierna tecnica delle costruzioni, senza considerare dunque le differenti caratteristiche che essi presentano a partire dalle metodologie utilizzate per la produzione dei materiali, fino ad arrivare alle differenze di calcolo progettuale. Se da un lato dunque sembra corretto l’utilizzo…
Course and Predictors of Pain and Physical Functioning in Patients with Hip Osteoarthritis: Systematic Review and Meta-Analysis
2016
Objective: To systematically summarize the literature on: (i) the course of pain and physical functioning; and (ii) predictors of deterioration of pain and physical functioning in patients with osteoarthritis of the hip. Methods: A literature search was conducted in PubMed, CINAHL, Embase, PsychINFO and SPORTDiscus up to July 2015. Meta-analyses and qualitative data syntheses were performed. Results: Eleven of the 15 included studies were of high quality. With regard to the course of pain and physical functioning, high heterogeneity was found across studies (I2 >71%) and within study populations (reflected by large standard deviations of change scores). Therefore, the course of pain and phy…
The Influence of Contextual Aspects in Talent Development: Interaction Between Relative Age and Birthplace Effects in NBA-Drafted Players
2021
The aims of this study were two-fold: (1) to inspect separately for the relative age and birthplace effects for players selected in the National Basketball Association (NBA) draft; (2) to explore the interaction among these factors and analyse this interaction in players' career performance. The database was obtained from the official records of the players (n = 1,738), who were selected during the annual editions of the NBA Draft from 1990 to 2019. The participants' date of birth was analyzed according to the month of birth and divided into four quartiles. The place of birth was compared to the distribution of the general population' places of birth based on different communities' sizes. C…
Propuesta de monitorización integral de la calidad ambiental del interior de la Iglesia de los Santos Juanes de Valencia
2020
Para la correcta conservación de los bienes de interés cultural (BIC), debe existir una óptima calidad ambiental interior. La monitorización de esta calidad ambiental, tradicionalmente, incluye el estudio de la humedad y la temperatura de los espacios interiores ya que es bien conocido que sus valores elevados y fluctuaciones rápidas pueden alterar los materiales constitutivos de las obras de arte. Sin embargo, hay muchos otros parámetros que se deben estudiar para tener una visión completa de los riesgos potenciales relacionados con ambientes patrimoniales. En este trabajo, planteamos la importancia de una monitorización integral sistemática de la calidad ambiental de un bien patrimonial q…