Search results for "199"

showing 10 items of 503 documents

Centre characteristics and procedure-related factors have an impact on outcomes of allogeneic transplantation for patients with CLL: a retrospective …

2017

Abstract Introduction:Even in the era of novel targeted therapies for the treatment of Chronic Lymphocytic Leukemia (CLL) patients, such as BTK, PI3K and BCL2 inhibitors, allogeneic hematopoietic stem cell transplantations (alloHCT) will remain an important treatment option for a subset of patients with very high risk CLL. The current study focused on the impact of center and procedure-related factors on outcomes after alloHCT, taking into account the impact of patient- and disease-related risk factors. Patients and Methods:Data of 684 CLL patients who received a first alloHCT between 2000 and 2011 were analyzed. Their data were collected as part of the EBMT CLL Data Quality Initiative. Out…

OncologyMaleTransplantation ConditioningCancer development and immune defence Radboud Institute for Molecular Life Sciences [Radboudumc 2]Chronic lymphocytic leukemiaMedizinQUALITY MANAGEMENT-SYSTEMKaplan-Meier Estimaterisk factor analysisGUIDELINESBiochemistryallogeneic stem cell transplantation; centre effects; chronic lymphocytic leukaemia; frailties; risk factor analysiscentre effectsTransplantation Conditioning / methods0302 clinical medicineRecurrenceRisk Factorsallogeneic stem cell transplantationLeukemia Lymphocytic Chronic B-Cell / mortalityRegistriesDelivery of Health Care / statistics & numerical dataIBRUTINIBddc:6160303 health sciencesALEMTUZUMABHazard ratioHematopoietic Stem Cell TransplantationProfessional PracticeHematologyMiddle Aged3. Good healthEurope030220 oncology & carcinogenesisABT-199CohortSURVIVALAlemtuzumabFemaleEurope / epidemiologymedicine.drugAdultmedicine.medical_specialtyAllogeneic transplantationImmunologyLower riskDIAGNOSISSettore MED/01 - Statistica Medica03 medical and health sciencesLeukemia Lymphocytic Chronic B-Cell / therapyHematopoietic Stem Cell Transplantation / methodsInternal medicinemedicineHumansKarnofsky Performance Status030304 developmental biologyAgedRetrospective Studiesbusiness.industryProportional hazards modelCHRONIC LYMPHOCYTIC-LEUKEMIARetrospective cohort studySTEM-CELL TRANSPLANTATIONCell Biologymedicine.diseaseLeukemia Lymphocytic Chronic B-CellConfidence intervalSurgeryProfessional Practice / statistics & numerical dataTransplantationbusinessDelivery of Health Carefrailtieschronic lymphocytic leukaemia030215 immunologyRESPONSES
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The taint of torture and the brazilian legal system

2019

In Brazil, the practice of torture intertwines deeply with its own history. The literature on the subject has had a greater intensification on its registers during the Dictatorial Regime (1964 to 1985). In spite of the Brazilian Constitution of 1988, Brazil only makes efforts to investigate the crimes of torture of this period to comply with the provisions of the United Nations in 2011. Within this scenario, the NationalTruth Commission (Law 12.528, of November 2011) was created with the purpose of clarifying the facts and circumstances of cases concerning human rights violations, as well as the Law on Access to Information (Law 12.527 of November 2011), which have regulated the constitutio…

Orden legal 37 491137-7038 8537 Arxius de sociologia 525290 2019 40 7038138 The taint of torture and the brazilian legal system De Góes BrennandEdna GusmãoTortureas well as the Law on Access to Information (Law 12.527 of November 2011)of November 2011) was created with the purpose of clarifying the facts and circumstances of cases concerning human rights violationssuch as tortureespecially because they were perpetrated by agents of the State. This article aims to present part of the research undertaken to understand the official legal procedures to prevent the practice of acts of torture in the national territory and how they are understood in the Brazilian legal systemUNESCO::SOCIOLOGÍADelamar José In Brazilwas created the Network Studies and Research on Violence-RIEV in partnership with Federal University of Paraíba-UFPB and Federal University of Santa Catarina-UFSC with the objective of investigating violations of human rights during the dictatorship1997 that criminalizes torture. ViolenceLegal orderthe practice of torture intertwines deeply with its own history. The literature on the subject has had a greater intensification on its registers during the Dictatorial Regime (1964 to 1985). In spite of the Brazilian Constitution of 1988Brazil only makes efforts to investigate the crimes of torture of this period to comply with the provisions of the United Nations in 2011. Within this scenariowhich have regulated the constitutional right to access public informationVolpato Dutrawith special attention to Law 9.455:SOCIOLOGÍA [UNESCO]the NationalTruth Commission (Law 12.528of April 7ViolenciaTorturavalid for all areas of the public administration. These laws allowed the opening of the archives of the dictatorship until denied on the basis of a severely restricted access. In this contextpersecution and violations of the right-to-live. The study of these violations is of fundamental importance for the historical unveiling of this period
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Algorithms, artificial intelligence and automated decisions concerning workers and the risks of discrimination: the necessary collective governance o…

2019

Big data, algorithms and artificial intelligence now allow employers to process information on their employees and potential employees in a far more efficient manner and at a much lower cost than in the past. This makes it possible to profile workers automatically and even allows technology itself to replace human resources personnel in making decisions that have legal effects on employees (recruitment, promotion, dismissals, etc.). This entails great risks of worker discrimination and defencelessness, with workers unaware of the reasons underlying any such decision. This article analyses the protections established in the EU General Data Protection Regulation (GDPR) for safeguarding emplo…

Organizational Behavior and Human Resource ManagementComputer sciencebusiness.industryCorporate governance05 social sciencesBig data050301 education02 engineering and technology020204 information systemsIndustrial relations0202 electrical engineering electronic engineering information engineeringData Protection Act 1998Profiling (information science)Process informationLower costArtificial intelligencebusiness0503 educationAlgorithmTransfer: European Review of Labour and Research
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The evaluation of workers by customers as a method of control and monitoring in firms: Digital reputation and the European Union's General Data Prote…

2021

As a method of surveillance and monitoring, the evaluation of workers by customers and employers and the disclosure of the results pose a series of challenges for the current legal framework of the European Union (EU). Employees subject to such evaluations are exposed to a far more intense and wider degree of monitoring of their work than traditional workers. The phenomenon arises from the adoption of a customer perspective, seeking to make work observable at all times, without any cost to firms. In this light, the author analyses the EU's General Data Protection Regulation, which establishes very specific restrictions when requesting and disclosing information about workers.

Organizational Behavior and Human Resource ManagementFreedom of informationStrategy and Managementmedia_common.quotation_subjectControl (management)Work (electrical)Management of Technology and InnovationGeneral Data Protection RegulationEmployee monitoringmedia_common.cataloged_instanceData Protection Act 1998BusinessEuropean unionMarketingmedia_commonReputationInternational Labour Review
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L’APPLICABILITÀ DELLA LEGGE N. 241/1990 AL PROCEDIMENTO TRIBUTARIO

2012

PROCEDIMENTO TRIBUTARIOSettore IUS/12 - Diritto TributarioLEGGE N. 241/1990
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Targeting of multiple myeloma-related angiogenesis by miR-199a-5p mimics: in vitro and in vivo anti-tumor activity

2014

// Lavinia Raimondi 1 , Nicola Amodio 1 , Maria Teresa Di Martino 1 , Emanuela Altomare 1 , Marzia Leotta 1 , Daniele Caracciolo 1 , Annamaria Gulla 1 , Antonino Neri 2 , Simona Taverna 3 , Patrizia D’Aquila 4 , Riccardo Alessandro 3 , Antonio Giordano 5 , Pierosandro Tagliaferri 1 and Pierfrancesco Tassone 1,5 . 1 Department of Experimental and Clinical Medicine, Magna Graecia University and Medical Oncology Unit, T. Campanella Cancer Center, Salvatore Venuta University Campus, Catanzaro, Italy 2 Department of Medical Sciences University of Milan, Hematology1, IRCCS Policlinico Foundation, Milan, Italy 3 Department of Pathology and Forensic and Medical Biotechnology, Section of Biology and…

Pathologymedicine.medical_specialtyStromal cellAngiogenesisMultiple Myeloma; microRNA AngiogenesisBlotting WesternEnzyme-Linked Immunosorbent AssayMice SCIDIn Vitro TechniquesBiologyReal-Time Polymerase Chain ReactionTransfectionMicemiR-199-5pCell MovementMice Inbred NODSettore BIO/13 - Biologia ApplicataCell Line TumorCell AdhesionmedicineAnimalsHumansHypoxiaCell adhesionProtein kinase BCell ProliferationPlasma cell leukemiaNeovascularization PathologicmicroRNA AngiogenesisMicroRNATransfectionPlasma cell leukemiamedicine.diseaseXenograft Model Antitumor AssaysMolecular medicineCell HypoxiaMicroRNAsmedicine.anatomical_structureOncologyAngiogenesis; Hypoxia; Microenviroment; MicroRNA; miR-199-5p; MiRNA; Multiple myeloma; Plasma cell leukemiaCancer researchFemaleAngiogenesisBone marrowMicroenviromentMiRNAMultiple MyelomaResearch Paper
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Profili penali e aspetti sostanziali in materia di reati di pedofilia. Analisi della legge 3 agosto 1998 n.268

2004

Lo studio ha come tema le modifiche operate dalla legge n. 268 del 1998 sui reati di c.d. pedofilia. L'analisi passa in rassegna gli aspetti sostanziali per poi soffermarsi ai peculiari meccanismi stabiliti sul versante processuale. L'approccio è adesivo all'intervento normativo sia per l'ingresso delle relative fattispecie tra i reati contro la persona, sia per l'indubbia tutela della vittima nell'accertamento dei reati.

Pedofilia - Legge n. 268 del 1998 . Reati contro la persona - Tutela dei minori - Profili processuale e disciplina sostanzialeSettore IUS/16 - Diritto Processuale Penale
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Poliittinen puhe kansalaisuudesta on usein puhetta palvelujärjestelmästä

2021

Kansalaisuuden käsitteellä on tehty politiikkaa suomalaisten puolueiden ohjelmissa jo 1800-1900-lukujen taitteesta alkaen. Eduskuntavaaliohjelmat ovat yksi areena, jossa puolueet määrittelevät neljän vuoden välein kansalaisuutta ja julkisen vallan suhdetta kansaan. Samalla puolueet luovat arvoihin perustuvia odotuksia siitä, millaisia kansalaisten tulisi olla. Kansalaisuuden kautta määrittyvät myös yhteiskuntapolitiikan sisällöt, sillä tulkinnat kansalaisista ja heidän tarpeistaan ohjaavat palveluiden ja etuuksien kokonaisuutta hyvinvointivaltiossa. nonPeerReviewed

Perussuomalaiset2010-lukuvaaliohjelmat (suunnitelmat)kansalaisuuspuolueetSuomen KeskustaeduskuntavaalitkansalaisyhteiskuntaKansallinen Kokoomus1990-luku2000-lukukansalaisethyvinvointivaltioSuomen Sosialidemokraattinen PuolueyhteiskuntapolitiikkaSuomipuolueohjelmatosallistuminen
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Obras de ficción, formas de conciencia y literatura

2017

espanol"Relatar lo ocurrido como invencion: una introduccion a la filosofia de la ficcion contemporanea (2016a)" ofrece al lector en castellano una magnifica oportunidad para familiarizarse con algunos aspectos centrales de la filosofia del lenguaje contemporanea y sus implicaciones para la teoria de la ficcion. Garcia-Carpintero recorre los argumentos fundamentales en favor y en contra de cada una de las posiciones relevantes, y nos propone finalmente un analisis alternativo de la norma de la ficcion y una teoria neofregeana de los terminos referenciales que logra esquivar algunas objeciones tradicionales. Esta discusion incluye, no obstante, dos objeciones a su norma de la ficcion: una se…

Philosophyassertionspeech actlcsh:Philosophy (General)Literaturalcsh:BC1-199referencelcsh:Logiclcsh:B1-5802Actes de parla (Lingüística)imaginationmetaphorCrítica (México D. F. En línea)
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Feasibility of Coulomb blockade thermometry in metrology

2000

Abstract Coulomb blockade thermometer (CBT) is a simple, magnetic-field-independent primary thermometer for everyday use at cryogenic temperatures. Its properties are well understood by now. The absolute accuracy at present is about ±0.5%. Recently, we have started studying the possibility of using CBT in metrological applications. We have especially in mind the future extension of the international temperature scale below 0.65 K, which is the lower end of ITS-90. Experiments with arrays containing more than 100 tunnel junctions in series are in progress in order to decrease the effects of electromagnetic environment and of co-tunnelling even below the present level.

PhysicsCondensed matter physicsElectromagnetic environmentAbsolute accuracyCoulomb blockadeThermometrySingle-electron effectsCondensed Matter PhysicsMetrologyEngineering physicsElectronic Optical and Magnetic MaterialsMetrologyInternational Temperature Scale of 1990ThermometerElectrical and Electronic EngineeringPhysica B: Condensed Matter
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