Search results for "1H"
showing 10 items of 1291 documents
Synthesis of Pyrrolo-Condensed Derivatives with Potential Antiviral Activity
2014
Structural investigations on diorgano- and triorganotin(IV) derivatives of [meso-tetra(4-sulfonatophenyl)porphine]metal chlorides.
2006
Abstract Several new complexes of organotin(IV) moieties with MCln[meso-tetra(4-sulfonatophenyl)porphine], (R2Sn)2MCln[meso-tetra(4-sulfonatophenyl)-porphinate]s and (R3Sn)4MCln [meso-tetra(4-sulfonatophenyl)porphinate]s, [M = Fe(III), Mn(III): n = 1, R = Me, n-Bu; Ph; M = Sn(IV): n = 2, R = Me, n-Bu] have been synthesized and their solid state configuration investigated by infrared (IR) and Mossbauer spectroscopy, and by 1H and 13C NMR in D2O. The electron density on the metal ion coordinated inside the porphyrin ring is not influenced by the organotin(IV) moieties bonded to the oxygen atoms of the side chain sulfonatophenyl groups, as it has been inferred on the basis of Mossbauer spectro…
Proteīndisulfīdizomerāzes A17 izoformas strukturālie un funkcionālie pētījumi
2020
Bakalaura darba mērķis ir izpētīt PDI A17 (AGR2) izoformas strukturālās un funkcionālās īpašības, pro-onkogēno proteīndisulfīdu izomerāžu (PDI) selektīvo inhibitoru meklēšanas projekta ietvaros. Šīm nolūkam izstrādāt protokolu PDI A17 iegūšanai aktīvā formā, un piemērot proteīnu kodolu magnētiskās rezonanses (KMR) spektroskopijas pētīšanas metodei. Izpētīt saistību starp neaktivēto un aktivēto aziridīn-2-karbonskābes atvasinājumiem un PDI A17 izoformu. Šajā darbā aprakstīta optimizētas PDI A17 izoformas iegūšana, pamatoti izvēlētie apstākļi un metodes proteīna-ligandu saistības testēšanai ar 2D 1H-15N-HSQC eksperimenta palīdzību. Darbā arī ir aprakstīti pirmie rezultāti par aziridīn-2-karbo…
Corrigendum to “The effect of silica nanoparticles on the morphology, mechanical properties and thermal degradation kinetics of PMMA [Pol. Degrad. St…
2012
Identificación de biomarcadores no invasivos de endometriosis mediante metabolómica por RMN
2015
La endometriosis es una enfermedad ginecológica crónica, estrógeno dependiente, asociada a dolor pélvico e infertilidad. Se define por la presencia de tejido endometrial fuera de la cavidad uterina y representa uno de los desórdenes ginecológicos benignos más comunes. Los síntomas de la endometriosis son altamente variables, inespecíficos y comunes en la población general, lo que contribuye a un retraso en el diagnóstico que oscila entre 8-12 años. Actualmente, el “patrón de oro” para el diagnóstico de la endometriosis es la cirugía, normalmente mediante laparoscopia. Sin embargo, se trata de un procedimiento invasivo, que implica riesgos potenciales y no es apropiado para el seguimiento pe…
A criterion for homeomorphism between closed Haken manifolds
2003
In this paper we consider two connected closed Haken manifolds denoted by M^3 and N^3, with the same Gromov simplicial volume. We give a simple homological criterion to decide when a given map f: M^3-->N^3 between M^3 and N^3 can be changed by a homotopy to a homeomorphism. We then give a convenient process for constructing maps between M^3 and N^3 satisfying the homological hypothesis of the map f.
On the topology of surfaces with the generalised simple lift property.
2020
In this paper, we study the geometry of surfaces with the generalised simple lift property. This work generalises previous results by Bernstein and Tinaglia, and it is motivated by the fact that leaves of a minimal lamination obtained as a limit of a sequence of properly embedded minimal disks satisfy the generalised simple lift property.
Reversible complexation of ethylene by a silylene under ambient conditions.
2014
Treatment of toluene solutions of the silylenes Si(SArMe6)2 (ArMe6 = C6H3-2,6(C6H2-2,4,6-Me3)2, 1) or Si(SArPri4)2 (ArPri4 = C6H3-2,6(C6H3-2,6-Pri2)2, 2) with excess ethylene gas affords the siliranes (ArMe6S)2tiebar above startSiCH2tiebar above endCH2 (3) or (ArPri4S)2tiebar above startSiCH2tiebar above endCH2 (4). Silirane 4 evolves ethylene spontaneously at room temperature in toluene solution. A Van’t Hoff analysis by variable-temperature 1H NMR spectroscopy showed that ΔGassn = −24.9(2.5) kJ mol–1 for 4. A computational study of the reaction mechanism using a model silylene Si(SPh)2 (Ph = C6H5) was in harmony with the Van’t Hoff analysis, yielding ΔGassn = −24 kJ mol–1 and an activatio…
Non-Classical Transformation of Benzendiazonium Hydrogen Sulfates. Access to 1,3-Dimethylisochromeno[4,3-c]pyrazol-5(1H)-one, a Potential Benzodiazep…
2013
The compound 2-((1,3-dimethyl-1H-pyrazol-5-yl)(methyl)carbamoyl)benzene-diazonium hydrogen sulfate (10) was reacted with copper sulfate and sodium chloride, in the presence of ascorbic acid as reducing agent, to afford a mixture of the chlorinated epimers 4′-chloro-2,2′,5′-trimethyl-2′,4′-dihydrospiro[isoindoline-1,3′-pyrazol]-3-one (18) and (19), the epimers 4′-hydroxy-2,2′,5′-trimethyl-2′,4′-dihydrospiro[isoindoline-1,3′-pyrazol]-3-one (20) and (21), and N-(1,3-dimethyl-1H-pyrazol-5-yl)benzamide (22). Under the foregoing conditions, diazonium salt 10 affords neither the 2-chloro-N-(1,3-dimethyl-1H-pyrazol-5-yl)-N-methylbenzamide (23) nor the tricyclic derivative 24, the classical products…
Comparing different processing methods in apple slice drying. Part 2 solid-state Fast Field Cycling 1H-NMR relaxation properties, shrinkage and chang…
2019
The objective of this paper was to study the effects of different drying methods that are: microwave (MW), hot air (HA) and a combination of both (HY), on the 1H-NMR relaxation properties, shrinkage and volatile compounds of Golden Delicious apple slices. Fast field cycling NMR relaxometry reveals that the HA samples dried at different temperatures (65 and 75 °C) appear to contain less restrained water as compared to the sample obtained by MW heating at the same temperatures. In fact, the longitudinal relaxation rates (T1) of the water molecules in the HA dried slices resulted shorter than those measured for the MW dried samples, thereby revealing that in the MW slices, water molecules beha…