Search results for "2(64)"
showing 10 items of 51 documents
Complement proteins regulating macrophage polarisation on biomaterials
2019
[EN] One of the events occurring when a biomaterial is implanted in an host is the protein deposition onto its surface, which might regulate cell responses. When a biomaterial displays a compromised biocompatibility, distinct complement pathways can be activated to produce a foreign body reaction. In this article, we have designed different types of biomaterial surfaces to study the inflammation process. Here, we used different concentrations of (3-glycidoxypropyl)-trimethoxysilane (GPTMS), an organically-modified alkoxysilane as a precursor for the synthesis of various types of sol-gel materials functionalizing coatings for titanium implants to regulate biological responses. Our results sh…
«Il sunt si biaus que c'en est une mervoie a voir». Zoologie e teratologie nel Devisement dou monde
2016
L’articolo ha come oggetto le descrizioni animali e teratologiche del Devisement dou monde. In particolare, la fauna poliana con le sue estremizzazioni mostruose e meravigliose viene indagata sul doppio filo del testo franco-italiano del Devisement (accompagnato, laddove necessario, dall’ausilio delle redazioni toscana e latina) e dell’iconografia rappresentata dalle miniature contenute in quattro codici del Devisement/Milione (mss. Royal 19 D I, Bodley 264, BNF fr. 2810, Arsenal 5219). The present article investigates animal and teratological descriptions of theDevisement dou monde. Particularly, Marco Polo’s fauna and its monstrous and marvelous extremes are explored both in the Franco-It…
TAFA4 relieves injury-induced mechanical hypersensitivity through LDL receptors and modulation of spinal A-type K+ current
2021
Pain, whether acute or persistent, is a serious medical problem worldwide. However, its management remains unsatisfactory, and new analgesic molecules are required. We show here that TAFA4 reverses inflammatory, postoperative, and spared nerve injury (SNI)-induced mechanical hypersensitivity in male and female mice. TAFA4 requires functional low-density lipoprotein receptor-related proteins (LRPs) because their inhibition by RAP (receptor-associated protein) dose-dependently abolishes its antihypersensitive actions. SNI selectively decreases A-type K+ current (IA) in spinal lamina II outer excitatory interneurons (L-IIo ExINs) and induces a concomitant increase in IA and decrease in hyperpo…
Mapping accretion and its variability in the young open cluster NGC 2264: A study based on u-band photometry
2014
We aim at characterizing the accretion properties of several hundred members of the star-forming cluster NGC 2264 (3 Myr). We performed a deep u,g,r,i mapping and a simultaneous u+r monitoring of the region with CFHT/MegaCam in order to directly probe the accretion process from UV excess measurements. Photometric properties and stellar parameters are determined homogeneously for about 750 monitored young objects, spanning the mass range 0.1-2 Mo. About 40% are classical (accreting) T Tauri stars, based on various diagnostics (H_alpha, UV and IR excesses). The remaining non-accreting members define the (photospheric+chromospheric) reference UV emission level over which flux excess is detecte…
Ja, det betyr noe hvem som underviser oss : En studie av hvordan (mis)matching av personlighetstype mellom foreleser og student kan påvirke studenten…
2021
Master's thesis in Innovation and knowledge development (ME513) Vår personlighet og den vi er spiller inn på atferden vår både i ulikesituasjoner og i samspill med andre, og påvirker dermed våre daglige liv. Dette bidrar til at forskning på mellommenneskelige samspill basert på personlighetstype er viktig. Trivselen og forståelsen til studenter er avgjørende for selve utdanningskvaliteten, og opplevd trivsel og forståelse kan derfor være svært viktig for å sikre individene i undervisningssituasjoner. Derfor vil en (mis)match av personlighetstype mellom foreleser og student kunne spille en rolle, men her er problemet at man ikke vet hvordan (mis)matching av personlighetstype mellom foreleser…
Enhancing social and health care educators’ competence in digital pedagogy: A pilot study of educational intervention
2021
The purpose of this pilot study was to explore connection of an educational intervention on the competence of health care educators and educator candidates (n=11) in digital pedagogy as a part of national TerOpe project. An educational intervention, Basics of Digital Pedagogy was developed by the TerOpe project’s experts. The participating educators and educator candidates of the educational intervention were recruited from the universities and university of applied sciences, which were involved in TerOpe project. All the participants of the educational interventions were invited to take part in this study. The educational intervention was conducted during spring 2019. Pre- and post-tests w…
Terveydenhuolto ja kyberuhkat
2019
Kyberturvallisuusstrategian vision mukaan Suomen tulee kyetä suojaamaan elintärkeät toimintonsa kyberuhkaa vastaan kaikissa tilanteissa. Terveydenhuolto on yksi elintärkeistä toiminnoista. Terveystoimiala on kyberhyökkäysten top-5-listalla ensimmäisenä. Hyökkäysten keskeisin motivaatio on potilastietojen arvo pimeillä markkinoilla. Vuonna 2015 varastettiin yli satamiljoonaa potilastietoa, jotka sisältävät rikollisille arvokkaita tietoja, kuten luottokorttinumeroita, työnantajatietoja ja sairaushistoriatietoja. Tässä artikkelissa kuvataan terveydenhuoltoon liittyviä kyberuhkia, kyberhaavoittuvuuksia ja toteutuneita kyberhyökkäyksiä kybermaailman eri ulottuvuudet kattaen. Tarkastelussa käytet…
Silicate modulates the cross-talk between osteoblasts (SaOS-2) and osteoclasts (RAW 264.7 cells): inhibition of osteoclast growth and differentiation
2012
It has been shown that inorganic monomeric and polymeric silica/silicate, in the presence of the biomineralization cocktail, increases the expression of osteoprotegerin (OPG) in osteogenic SaOS-2 sarcoma cells in vitro. In contrast, silicate does not affect the steady-state gene expression level of the osteoclastogenic ligand receptor activator of NF-κB ligand (RANKL). In turn it can be expected that the concentration ratio of the mediators OPG/RANKL increases in the presence of silicate. In addition, silicate enhances the growth potential of SaOS-2 cells in vitro, while it causes no effect on RAW 264.7 cells within a concentration range of 10-100 µM. Applying a co-cultivation assay system,…
H.264 QoS and Application Performance with Different Streaming Protocols
2015
Streaming techniques, including the selected streaming protocol, have an effect on the streaming quality. In this study, the performance of three different streaming protocols in a disturbed communication channel is evaluated with a modified version of the FFPlay player. A H.264 encoded video is used as a test sequence. The number of displayed image frames, the frame rate and playout duration are used as objective metrics for QoS. The metrics brings out differences of streaming protocols in our test environment. They are measured at the application level and have a connection to the user experience. peerReviewed
In-Depth Characterization of Bioactive Extracts from Posidonia oceanica Waste Biomass
2019
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