Search results for "2-diol"
showing 10 items of 46 documents
CCDC 807437: Experimental Crystal Structure Determination
2011
Related Article: R.Outouch, B.Boualy, M.A.Ali, L.E.Firdoussi, C.Rizzoli|2011|Acta Crystallogr.,Sect.E:Struct.Rep.Online|67|o195|doi:10.1107/S1600536810052323
CCDC 701231: Experimental Crystal Structure Determination
2009
Related Article: O.Wichmann, A.Lehtonen|2009|Inorg.Chem.Commun.|12|15|doi:10.1016/j.inoche.2008.10.019
Aspartilproteāžu inhibitoru sintēze
2021
Aspartilproteāžu inhibitoru sintēze. Bojārs M., zinātniskais vadītājs MSc. chem. Kovada V. Bakalaura darbs, 57 lappuses, 45 attēli, 38 literatūras avoti. Latviešu valodā. Bakalaura darba ietvaros sintezēts aspartilproteāžuu inhibitori, kas ir potenciāli pretmalārijas zāļu vielas kandidāts. Veikti secinājumi par pielietotajām metodēm tā sintēzei.
Nanocomplexes for gene therapy of respiratory diseases: Targeting and overcoming the mucus barrier
2015
Gene therapy, i.e. the delivery and expression of therapeutic genes, holds great promise for congenital and acquired respiratory diseases. Non-viral vectors are less toxic and immunogenic than viral vectors, although they are characterized by lower efficiency. However, they have to overcome many barriers, including inflammatory and immune mediators and cells. The respiratory and airway epithelial cells, the main target of these vectors, are coated with a layer of mucus, which hampers the effective reaching of gene therapy vectors carrying either plasmid DNA or small interfering RNA. This barrier is thicker in many lung diseases, such as cystic fibrosis. This review summarizes the most impor…
Crystal structure of (1S,2R,4S)-1-[(morpholin-4-yl)methyl]-4-(prop-1-en-2-yl)cyclohexane-1,2-diol
2014
Besides intramolecular O—H⋯N hydrogen bonds, the crystal structure displays intermolecular O—H⋯O and C—H⋯O hydrogen bonds linking the molecules into undulating layers parallel to the (01) plane.
Stereoselective synthesis and transformation of pinane-based 2-amino-1,3-diols
2021
A library of pinane-based 2-amino-1,3-diols was synthesised in a stereoselective manner. Isopinocarveol prepared from (−)-α-pinene was converted into condensed oxazolidin-2-one in two steps by carbamate formation followed by a stereoselective aminohydroxylation process. The relative stereochemistry of the pinane-fused oxazolidin-2-one was determined by 2D NMR and X-ray spectroscopic techniques. The regioisomeric spiro-oxazolidin-2-one was prepared in a similar way starting from the commercially available (1R)-(−)-myrtenol (10). The reduction or alkaline hydrolysis of the oxazolidines, followed by reductive alkylation resulted in primary and secondary 2-amino-1,3-diols, which underwent a reg…
CCDC 820755: Experimental Crystal Structure Determination
2011
Related Article: F.Riobe, F.Piron, C.Rethore, A.M.Madalan, C.J.Gomez-Garcia, J.Lacour, J.D.Wallis, N.Avarvari|2011|New J.Chem.|35|2279|doi:10.1039/c1nj20310j
CCDC 198063: Experimental Crystal Structure Determination
2004
Related Article: A.Lehtonen, R.Sillanpaa|2003|Polyhedron|22|2755|doi:10.1016/S0277-5387(03)00373-5
CCDC 820753: Experimental Crystal Structure Determination
2011
Related Article: F.Riobe, F.Piron, C.Rethore, A.M.Madalan, C.J.Gomez-Garcia, J.Lacour, J.D.Wallis, N.Avarvari|2011|New J.Chem.|35|2279|doi:10.1039/c1nj20310j
CCDC 2149491: Experimental Crystal Structure Determination
2022
Related Article: Ida Mattsson, Manu Lahtinen, Ruzal Sitdikov, Bianca Wank, Tiina Saloranta-Simell, Reko Leino|2022|Carbohydr.Res.|518|108596|doi:10.1016/j.carres.2022.108596