Search results for "228"

Could allergen-specific immunotherapy benefit from the use of nanocarriers?

2016

Allergen-specific immunotherapy: challenges The total number of people suffering from allergic diseases increased dramatically during recent decades. Allergic reactions of the immediate type (type I hypersensitivity reactions according to classification by Coombs and Gell) involve an overreaction of the immune system and the formation of IgE

Single-Cell Transcriptional Profiling of Cells Derived From Regenerating Alveolar Ducts

2020

Lung regeneration occurs in a variety of adult mammals after surgical removal of one lung (pneumonectomy). Previous studies of murine post-pneumonectomy lung growth have identified regenerative “hotspots” in subpleural alveolar ducts; however, the cell-types participating in this process remain unclear. To identify the single cells participating in post-pneumonectomy lung growth, we used laser microdissection, enzymatic digestion and microfluidic isolation. Single-cell transcriptional analysis of the murine alveolar duct cells was performed using the C1 integrated fluidic circuit (Fluidigm) and a custom PCR panel designed for lung growth and repair genes. The multi-dimensional data set was …

Physical capacity in performing daily activities is reduced in scleroderma patients with early lung involvement

2015

Background and Aims Patients with systemic sclerosis (SSc) often complain reduced capacity at submaximal exercise; conversely, physical capacity in performing daily duties has never been measured in SSc. The aim of this study is to evaluate this performance and its correlates, in patients with SSc compared with healthy controls, in a free-living setting. Methods Twenty-seven outpatients with stable SSc and 11 controls were recruited. Physical activity was assessed by portable multiple sensor device (SenseWear Armband) worn for at least 6 days. Physical activity duration (PAD; in minutes) for non-sedentary activities and physical activity level (PAL = total daily energy/resting energy expend…

Organisation des structures de soins transversales en allergologie en France en 2020

2021

Resume Introduction Les allergies touchent 25 % de la population generale avec une augmentation des allergies severes. Le developpement en France de structures de soins transversales en allergologie pour une prise en charge pluridisciplinaire des patients repond a un besoin de sante publique. Notre travail a pour but de faire un etat des lieux de ces structures. Methodes Enquete descriptive par questionnaire envoye aux chefs de services de structures de soins soit avec une activite principale en allergologie, soit avec une activite variee en allergologie. L’enquete portait sur l’organisation administrative, les equipes medicales et paramedicales, l’offre de soins et les moyens techniques de…

15. Mainzer Allergie-Workshop 2003

2003

L’échographie en réhabilitation, une émergence anglo-saxonne

2017

Resume L’echographie est un outil qui a vu le jour dans les annees 1950 en medecine, et depuis s’est considerablement developpe pour de nombreuses professions de sante dont les kinesitherapeutes. Son accessibilite, son absence d’effet secondaire et son faible cout en font un moyen d’evaluation indispensable pour les kinesitherapeutes explorant les alterations du mouvement et cherchant a ameliorer la pertinence du plan de traitement propose aux patients. De nombreux pays ont deja œuvre dans le sens de l’amelioration de la formation et de la pratique en echographie pour les kinesitherapeutes. L’integration du developpement de cet outil en France doit necessairement passer par des collaboratio…

Hereditäres Angioödem in einer Familie mit spezifischen Mutationen sowohl im Plasminogen‐ als auch im SERPING1‐Gen

2020

Food allergy and atopic dermatitis phenotypes according to molecular allergology: Lessons from cohort around the world

2020

International audience

N-terminal hevein-like domains (4.3 kDa) but not 31 kDa endochitinases are responsible for IgE-mediated in vitro and in vivo reactions in latex-fruit…

2005

Latex allergy: the sum quantity of four major allergens shows the allergenic potential of medical gloves

2007

Background:  Assessment of allergenic potential of medical devices made of natural rubber latex (NRL) requires the measurement of concentrations of specific allergenic proteins or polypeptides eluting from rubber. Methods:  Four NRL allergens (Hev b 1, 3, 5, and 6.02) were quantified in all medical glove brands marketed in Finland in 1999, 2001, and 2003 (n = 208) by a capture enzyme immunoassay. The results were compared with those obtained from previous nationwide market surveys, using a skin prick test-validated human IgE-based ELISA-inhibition method. Results:  A high overall correlation (r = 0.87, 95% CI 0.83–0.90) emerged between the sum values of the four allergens(μg/g glove) and Ig…