Search results for "2400"

showing 3 items of 23 documents

Caracterización genómica del microalga Trebouxia sp. TR9 aislada del liquen Ramalina farinacea (L.) Ach. mediante secuenciación masiva

2015

Los líquenes son complejas entidades simbióticas originadas por asociaciones cíclicas e interacciones positivas de organismos muy diferentes, un hongo heterotrófico y uno o varios “fotobiontes” autótrofos fotosintéticos, tanto algas verdes unicelulares, como cianobaterias o ambos. Además, comunidades específicas de bacterias aparecen como simbiontes obligados de líquenes. En todos los talos del liquen Ramalina farinacea (L.) Ach., coexisten las dos mismas especies de algas Trebouxia (T. jamesii -TR1- y Trebouxia sp. TR9). Esta forma de asociación simbiótica específica y selectiva es interesante como modelo de la coexistencia de dos especies diferentes de Trebouxia dentro de un mismo talo li…

genomamitocondriacloroplastonúcleo240000secuenciaciónanotaciónliquenmicroalga
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Vesiclepedia:A Compendium for Extracellular Vesicles with Continuous Community Annotation

2012

Vesiclepedia is a community-annotated compendium of molecular data on extracellular vesicles.

human proteinpedia; exosomal proteins; delivery-system; breast-milk; url decay; cells; microvesicles; update; rna; biogenesisQH301-705.5Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology) Molecular Biology Microbiology Biochemistry or Biopharmacy)610 Medicine & healthApoptosisComputational biology1100 General Agricultural and Biological SciencesBiologyVesiclepediaExosomesExosomeGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciencesAnnotation0302 clinical medicineSDG 3 - Good Health and Well-being1300 General Biochemistry Genetics and Molecular Biology2400 General Immunology and MicrobiologyCommunity PageExoCartaBiology (General)Medicinsk bioteknologi (med inriktning mot cellbiologi (inklusive stamcellsbiologi) molekylärbiologi mikrobiologi biokemi eller biofarmaci)BiologyBiología y Biomedicina030304 developmental biologyUncategorized0303 health sciencesGeneral Immunology and MicrobiologyGeneral NeuroscienceMicrovesicleResearch2800 General NeuroscienceExtracellular vesicle11359 Institute for Regenerative Medicine (IREM)Extracellular vesiclesMicrovesiclesCompendiumCell biologyData sharingDatabases as Topic030220 oncology & carcinogenesisGeneral Agricultural and Biological SciencesExtracellular Space
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Single-cell analysis of population context advances RNAi screening at multiple levels

2012

Isogenic cells in culture show strong variability, which arises from dynamic adaptations to the microenvironment of individual cells. Here we study the influence of the cell population context, which determines a single cell's microenvironment, in image‐based RNAi screens. We developed a comprehensive computational approach that employs Bayesian and multivariate methods at the single‐cell level. We applied these methods to 45 RNA interference screens of various sizes, including 7 druggable genome and 2 genome‐wide screens, analysing 17 different mammalian virus infections and four related cell physiological processes. Analysing cell‐based screens at this depth reveals widespread RNAi‐induce…

toImage ProcessingDruggabilityGenomeImage analysis0302 clinical medicineComputer-AssistedSX00 SystemsX.ch2604 Applied MathematicsSingle-cell analysisRNA interferenceModels2400 General Immunology and MicrobiologyImage Processing Computer-AssistedViralRNA Small Interfering0303 health scienceseducation.field_of_studyApplied MathematicsSystems BiologyGenomics10124 Institute of Molecular Life SciencesCell biologycell variabilityComputational Theory and MathematicsCellular MicroenvironmentVirus DiseasesVirusesRNA ViralRNA InterferenceSingle-Cell AnalysisGeneral Agricultural and Biological SciencesInformation SystemsSystems biologyVirus infectionPopulationContext (language use)Genomics1100 General Agricultural and Biological SciencesBiologySmall InterferingModels BiologicalGeneral Biochemistry Genetics and Molecular BiologySX08 LipidX03 medical and health sciencesViral ProteinsCell-to-cell variability; Image analysis; Population context; RNAi; Virus infection1300 General Biochemistry Genetics and Molecular BiologyHumansComputer Simulationeducation030304 developmental biologyGeneral Immunology and MicrobiologyCell-to-cell variabilityReproducibility of ResultsBayes TheoremcellBiologicalPopulation contextRNAi570 Life sciences; biologyRNA030217 neurology & neurosurgeryHeLa CellsMolecular Systems Biology
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