Search results for "243"

showing 3 items of 43 documents

The European External Action Service: Torn apart between several principals or acting as a smart 'double-agent'?

2014

Published version of an article in the journal: Journal of Contemporary European Research. Also available from the publisher at: http://www.jcer.net/index.php/jcer/article/view/605/494 Open Access The European External Action Service (EEAS) is a hybrid and compound institutional actor in the EU’s multi-level administration with delegated authority from the member states (MS) to conduct the EU’s external action. Substantial competences, notably in the field of Neighbourhood and Trade policies, as well as Development and Cooperation remain under the control of the European Commission (Commission). At the same time, also Members of the European Parliament (EP) are more clearly voicing their in…

international bureaucraciesEU foreign policyprincipal-Agent theoryVDP::Social science: 200::Political science and organizational theory: 240::International politics: 243EEASorganizational autonomy
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AGE6. Skin Ageing: Focus on the Role of Inflammatory Genetic Factors in Cutaneous Neoplasia

2014

AGE6. Skin Ageing: Focus on the Role of Inflammatory Genetic Factors in Cutaneous Neoplasia C. M. Gambino1, F. Crapanzano1, G. Accardi1, A. Aiello1, C. Virruso1, G. Pistone1, M. R. Bongiorno1, D. Lio1, C. R. Balistreri1, G. Candore1 1University of Palermo, Palermo, Italy Background: Skin aging is a complex process that involves intrinsic and exogenous causes. Photo-oxidative damage caused by UV is the leading cause of extrinsic aging of the skin, known as photo-ageing. UV damages can be linked mostly to overproduction of ROS that induces a complex molecular cascade able to accelerate physiological aging, determining a typical dermal/epidermal inflammation with an increased risk of getting s…

rs.4986790) TLR4 (+1196 C/T rs.4986791) MMP2 (-1306 C/T rs.243865) and MMP9 (-1562 C/T rs.3918242)SNPsSkin aging TLR4 (+896 A/G; rs.4986790) TLR4 (+1196 C/T rs.4986791) MMP2 (-1306 C/T rs.243865) and MMP9 (-1562 C/T rs.3918242)SNPsSkin aging TLR4 (+896 A/G
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Genetic Factors as Promising Biomarkers of Sporadic Ascending Aortic Aneurysm

2014

Thoracic aorta shows various changes with advancing age and a progressive deterioration in structure and function. As a result, vascular remodeling (VR) and medial degeneration (MD) occur. VR and MD are typical entities of sporadic thoracic aortic aneurysm (TAA), actually considered a common and serious health risk and a pathology by unclear mechanisms. Increased activity of the coagulation system, inflammation, activation of extracellular matrix remodeling and endothelial dysfunction pathways have been recently evidenced to have a key role in its onset. Thus, polymorphisms of the coagulation system [fibrinogen (rs1800790); Factor II ( rs1799963); Factor V (rs6025); Factor VII (rs121964926)…

tPA ( rs2020918)ACE (rs1799752)]PAI-1 (rs1799768)TAFI (rs2146881)] inflammation [TLR4 (rs4986790)Factor V (rs6025)CCR5 (rs333)] extra-cellular matrix remodeling [MMP9 (rs3918242)vascular remodeling (VR) and medial degeneration (MD)sporadic thoracic aortic aneurysm (TAA)polymorphisms of the coagulation system [fibrinogen (rs1800790)MMP2 (rs243865)] endothelium dysfunction [eNOs (rs 1799983)Factor II ( rs1799963)Factor VII (rs121964926)
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