Search results for "24"

showing 10 items of 3907 documents

Purification and characterization of the mda-7 tumor suppressor protein expressed in insect cells

2008

solutohjelmoitunut solukuolemaIL-24mda-7apoptosishyönteisetcancer therapysyöpätauditcancer cell
researchProduct

Evaluation of the Behavior of Phenolic Compounds and Steviol Glycosides of Sonicated Strawberry Juice Sweetened with Stevia (Stevia rebaudiana Berton…

2019

In this study, the influence of stevia addition and sonication processing parameters on the phenolic content and profile as well as the steviol glycosides of strawberry juice-based samples was investigated. For this purpose, three matrices&mdash

sonicationSonicationgreen stevia powder ; strawberry juice ; antioxidant compounds ; steviol glycosides ; sonicationPharmaceutical ScienceSteviol01 natural sciencesFragariaArticleAntioxidantsAnalytical Chemistrylcsh:QD241-441chemistry.chemical_compound0404 agricultural biotechnologylcsh:Organic chemistryantioxidant compoundsGlucosidesPhenolsDrug DiscoveryFood scienceSteviosidePhysical and Theoretical Chemistrysteviol glycosidesstrawberry juiceChromatography High Pressure Liquidchemistry.chemical_classificationFlavonoidsbiologyPlant Extracts010401 analytical chemistryOrganic ChemistryGlycoside04 agricultural and veterinary sciencesSweetnessgreen stevia powderbiology.organism_classification040401 food scienceStevia0104 chemical sciencesStevia rebaudianachemistryChemistry (miscellaneous)Molecular MedicineKaempferolDiterpenes KauraneMolecules
researchProduct

Discovery of a new class of sortase a transpeptidase inhibitors to tackle gram-positive pathogens: 2-(2-phenylhydrazinylidene)alkanoic acids and rela…

2016

A FRET-based random screening assay was used to generate hit compounds as sortase A inhibitors that allowed us to identify ethyl 3-oxo-2-(2-phenylhydrazinylidene)butanoate as an example of a new class of sortase A inhibitors. Other analogues were generated by changing the ethoxycarbonyl function for a carboxy, cyano or amide group, or introducing substituents in the phenyl ring of the ester and acid derivatives. The most active derivative found was 3-oxo-2-(2-(3,4dichlorophenyl)hydrazinylidene)butanoic acid (2b), showing an IC50 value of 50 µM. For a preliminary assessment of their antivirulence properties the new derivatives were tested for their antibiofilm activity. The most active compo…

sortase A; biofilms; 2-(2-phenylhydrazinylidene)alkanoic acid derivatives; FRET0301 basic medicineStaphylococcus aureusStereochemistryPharmaceutical ScienceRelated derivativesmedicine.disease_causeSettore BIO/19 - Microbiologia Generale01 natural sciencesArticleAnalytical Chemistrylcsh:QD241-441Inhibitory Concentration 5003 medical and health scienceschemistry.chemical_compound2-(2-phenylhydrazinylidene)alkanoic acid derivativeAnti-Infective AgentsBacterial Proteinslcsh:Organic chemistryStaphylococcus epidermidisAmideDrug DiscoveryStaphylococcus epidermidismedicineEnzyme InhibitorsPhysical and Theoretical ChemistryIC50Grambiology010405 organic chemistryChemistryBiofilmSortase AOrganic ChemistryBiofilmAminoacyltransferasesbiology.organism_classificationSettore CHIM/08 - Chimica Farmaceutica2-(2-phenylhydrazinylidene)alkanoic acid derivativesPhenylhydrazines0104 chemical sciencesCysteine Endopeptidases030104 developmental biologyChemistry (miscellaneous)Staphylococcus aureusSortase AFRETMolecular Medicinebiofilms
researchProduct

The Relationship between Public Value and Change : Case Study on Public Value Creation in Relation to the Regional Government, Health and Social Serv…

2019

Master's thesis Innovative governance and public management ME523 - University of Agder 2019 A break first from Traditional Public Administration (TPA) and later New Public Management (NPM) has gradually offered new angles to the governance. For instance, Moorecreated an analogue to the private value creation,and as a result, the ideology of public value creation has emerged worldwide.Since then, scholars have developed a conceptual understanding of public value. Compared to the NPM public value management embraces post-competitive achievements and broader governmental goals. Yet, the empirical research on public value management, especially in the Finnish context, is rather unknown.This st…

sosiaali- ja terveydenhuollon uudistusmeasuring public valueMaakuntauudistuspublic value managementPublic Value ManagementVDP::Samfunnsvitenskap: 200::Statsvitenskap og organisasjonsteori: 240::Offentlig og privat administrasjon: 242value co-creationSosiaali-ja terveydenhuollon uudistusregional government health and social services reformMeasuring Public ValueRegional Governmentregional studiesRegional StudiesValue Co-creationHealth and Social Services ReformME523
researchProduct

Mental health profiles of Finnish adolescents before and after the peak of the COVID-19 pandemic

2023

Abstract Background The COVID-19 pandemic has had implications for adolescents’ interpersonal relationships, communication patterns, education, recreational activities and well-being. An understanding of the impact of the pandemic on their mental health is crucial in measures to promote the post-pandemic recovery. Using a person-centered approach, the current study aimed to identify mental health profiles in two cross-sectional samples of Finnish adolescents before and after the peak of the pandemic, and to examine how socio-demographic and psychosocial factors, academic expectations, health literacy, and self-rated health are associated with the emerging profiles. Methods and findings Surv…

sosiodemografiset tekijätCOVID-19COVID-19 pandemicterveysosaaminenpsykososiaaliset tekijätsocial relationshipspandemiat3124 Neurology and psychiatrysosiaaliset suhteetAdolescencePsychiatry and Mental healthCluster analysisnuoretmielenterveyspoikkeusolot3123 Gynaecology and paediatricsSocial relationshipsPediatrics Perinatology and Child HealthadolescenceklusterianalyysiMental healthmental healthcluster analysisChild and Adolescent Psychiatry and Mental Health
researchProduct

Optical Monitoring of Microplastics Filtrated from Wastewater Sludge and Suspended in Ethanol.

2021

The abundance of microplastics (MPs) in the atmosphere, on land, and especially in water bodies is well acknowledged. In this study, we establish an optical method based on three different techniques, namely, specular reflection to probe the medium, transmission spectroscopy measurements for the detection and identification, and a speckle pattern for monitoring the sedimentation of MPs filtrated from wastewater sludge and suspended in ethanol. We used first Raman measurements to estimate the presence and types of different MPs in wastewater sludge samples. We also used microscopy to identify the shapes of the main MPs. This allowed us to create a teaching set of samples to be characterized …

spectroscopylieteoptical monitoringmicroplasticsetanolispektroskopiasedimentointimonitorointisedimentitjätevesiwater qualityArticlejätevesilietelcsh:QD241-441mikromuovitlcsh:Organic chemistryplasticmeasuring methodshavainnointitransmittancesewageseurantamutapolymeeritwastewaterpolymerssewage sludgemittaussedimentstrackingvedenlaatuoptical methodopticsmittausmenetelmätmikroroskatoptiikkasludgeoptiset laitteetilmaisimetmuoviRaman spectroscopysedimentaatiomeasurementethanolliejusedimentationlaser speckle patternjätemuoviPolymers
researchProduct

Social psychological aspects of ACL injury prevention and rehabilitation: An integrated model for behavioral adherence

2017

Managing rehabilitation for ACL injury is dependent on uptake of, and compliance with, medical and safety recommendations. In this paper, we propose a multi-theory model that integrates self-determination theory and the theory of planned behavior to identify the motivational determinants ACL injury prevention and management behaviors and the processes involved. nonPeerReviewed

sport injuriessocial cognitive factorsmedicine.medical_specialtyPhysical Injury - Accidents and Adverse Effectsmedicine.medical_treatmentehkäisyBioengineeringPhysical Therapy Sports Therapy and RehabilitationCompliance (psychology)03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationpreventionBehavioral and Social ScienceSocial cognitive factorsmedicineOrthopedics and Sports MedicineBehavioral compliance030212 general & internal medicinelcsh:Sports medicinebehavioral complianceta315ta515Treatment motivationRehabilitationbusiness.industryPreventionRehabilitationTheory of planned behaviorInjuries and accidents030229 sport sciencesmusculoskeletal systemmedicine.diseaseACL injurytheoretical integrationGood Health and Well BeingSport injury prevention and rehabilitationtreatment motivationPerspectivePhysical therapyTreatment motivationkuntoutusTheoretical integrationPsychological aspectslcsh:RC1200-1245businessAsia-Pacific Journal of Sports Medicine, Arthroscopy, Rehabilitation and Technology
researchProduct

Technical, tactical and spatial indicators related to goal scoring in European elite soccer

2020

The aim of this study was to describe the technical, tactical and spatial indicators related to goal scoring in elite European soccer, considering the type of defence and the positioning of the opponent. For the analysis, 8 tactical dimensions related to the final actions in 380 sequences that led to goal during the UEFA Champions League were evaluated by observational methodology. 75.9% of the goals were scored from open play and 24.1% were scored from set pieces. Collective actions produced 51.6% of the total goals while individual actions produced 10.5% of goals. Regarding the penultimate action, crosses were more frequent against organized defences, while passes in behind the defence, o…

sports performanceApplied psychologyscoring opportunitiesPhysical Therapy Sports Therapy and Rehabilitationmatch analysisLeague03 medical and health sciences0302 clinical medicineNotational analysisassociation footballEducación Física y Deportivalcsh:Sports medicineObservational methodologySports performance030229 sport sciencesAdversaryCircumstantial evidenceAssociation footballMatch analysisMatch analysisScoring opportunitiesEliteNotational analysisnotational analysisPsychologylcsh:RC1200-1245030217 neurology & neurosurgeryJournal of Human Sport and Exercise
researchProduct

Heterogeneous photocatalysis: guidelines on experimental setup, catalyst characterization, interpretation, and assessment of reactivity

2019

Soon after the publication of the first pioneering works on heterogeneous photocatalysis, the number of papers on this topic continuously increased. This intriguing field of research is very complex as it endows with an interdisciplinary overview that involves different aspects of chemistry, physics, material and environmental sciences. Even if photocatalytic applications in real processes are often difficult to be implemented and scaled-up, investigations at laboratory scale are easy to be performed, and in some cases they may give rise to misconceptions. For this reason, the present work aims to sum up most of the common experimental techniques and procedures generally used in heterogeneo…

standardizationcharacterization techniqueSettore ING-IND/24 - Principi Di Ingegneria ChimicaChemistryProcess Chemistry and TechnologyChemistry (all)Nanotechnology02 engineering and technologyGeneral Chemistry010402 general chemistry021001 nanoscience & nanotechnology01 natural sciencesHeterogeneous photocatalysiCatalysisCatalysi0104 chemical sciencesCatalysisCharacterization (materials science)Photocatalysisengineering aspectexperimental procedureSettore CHIM/07 - Fondamenti Chimici Delle Tecnologie0210 nano-technology
researchProduct

Uretroplastica con innesto dorsale di mucosa buccale: è ancora il metodo di scelta nella stenosi uretrale a lungo termine? – P18.

2015

INTRODUZIONE E OBIETTIVO DELLO STUDIO: Risultati a lungo termine dell'uretroplastica con innesto dorsale di mucosa buccale e fattori predittivi negativi della metodica. MATERIALI E METODI: Analisi retrospettiva di 27 pazienti sottoposti a uretroplastica con innesto di mucosa buccale (prelievo del graft della guancia di circa 4x2,5 cm) per stenosi uretrale nel periodo 2010-2015 (mediana 42 mesi). Flusso massimo (Qmax), residuo post-minzionale (RPM), ecografia del corpo spongioso uretrale, test IPSS (solo domanda su QoL) e percezione soggettiva allo svuotamento sono stati ottenuti prima e dopo l’intervento (un mese e dopo mediana di 3,5 anni). L’età media del campione era di 43,2 anni (range …

stenosi uretraleuretroplasticainnestoSettore MED/24 - Urologia
researchProduct