Search results for "24"

Varicocele ed Infertilità

2013

Internalization of novel non-viral vector TAT-streptavidin into human cells

2007

BMC Biotechnology, 7 (1)

Human Papillomavirus Types 16, 18, and 31 Share Similar Endocytic Requirements for Entry

2013

ABSTRACT Human papillomavirus type 18 (HPV18), one of the HPVs with malignant potential, enters cells by an unknown endocytic mechanism. The key cellular requirements for HPV18 endocytosis were tested in comparison to those for HPV16 and -31 endocytoses. HPV18 (like HPV16 and -31) entry was independent of clathrin, caveolin, dynamin, and lipid rafts but required actin polymerization and tetraspanin CD151, and the viruses were routed to the same LAMP-1-positive compartment. Hence, the viruses shared similar cellular requirements for endocytic entry.

Clathrin- and Caveolin-Independent Entry of Human Papillomavirus Type 16—Involvement of Tetraspanin-Enriched Microdomains (TEMs)

2008

BACKGROUND: Infectious entry of human papillomaviruses into their host cells is an important step in the viral life cycle. For cell binding these viruses use proteoglycans as initial attachment sites. Subsequent transfer to a secondary receptor molecule seems to be involved in virus uptake. Depending on the papillomavirus subtype, it has been reported that entry occurs by clathrin- or caveolin-mediated mechanisms. Regarding human papillomavirus type 16 (HPV16), the primary etiologic agent for development of cervical cancer, clathrin-mediated endocytosis was described as infectious entry pathway. METHODOLOGY/PRINCIPAL FINDINGS: Using immunofluorescence and infection studies we show in contra…

Sähköpostin avulla perustelevaan keskusteluun?

1997

Vuorovaikutus muiden ihmisten kanssa edistää argumentointitaitojen ja kriittisen ajattelun kehittymistä. Entä kun vuorovaikutus tapahtuu sähköpostin avulla? – Kirjoittaja väitteli kasvatustieteiden tohtoriksi 7.6.1997 Jyväskylän yliopistossa. Väitöskirjan aiheena oli Studying argumentation in higher education by electronic mail.

Prescription opioid use and employment : A nationwide Finnish register study

2021

Background: The secular decline in labor market participation and the concurrent increase in opioid use in many developed countries have sparked a policy debate on the possible connection between these two trends. We examined whether the use of prescription opioids was connected to labor market outcomes relating to participation, employment and unemployment among the Finnish population. Methods: The working-age population (aged 19–64 years) living in Finland during the period 1995–2016 was used in the analyses (consisting of 67 903 701 person-year observations). Lagged values of prescription opioid use per capita were used as the exposure. Instrumental variables (IV) estimation method was u…

Mīļais Misiņa kungs!

1914

Vēstulē P. Šmits stāsta par "Etnografisku rakstu krājuma" 2. daļas rakstiem, kā arī lūdz bibliofilu J. Misiņu pameklēt A. Hupeļa rakstu, atsūtīt kalendāru 1914. gadam. Tie varētu būt gan P. Strautzeļa, gan Zvārguļa vai J. Gūžas sastādītie kalendāri. Vēl lūgums pēc "Dienas Lapas" etnogrāfiskajiem pielikumiem.

Dantes laikmets tālajos austrumos

1921

P. Šmita raksts par Dantes laikmetu tālajos austrumos publicēts "Dante : rakstu krājums 600 gadu nāves dienas piemiņai (Rīga : Dantes svētku komiteja, 1921). Tajā salīdzināts laikmets Eiropā un tālajos austrumos, skatot to no Dantes dzīves laika - tā laika literatūra, zinātne, ceļojumi u.tml.

The role of the agreement as a tool for management of property relations in cases of cross border marriages and civil unions/partnerships registered …

2021

The essay examines the role of the agreement as a tool for managing property relationships in crossborder marriages and registered partnerships, in light of EU Regulations 1103 and 1104 of 2016, on the property regimes of international married or registered couples. The main prerogative of such acts is the recognition of the parties? freedom to choose the court and the applicable law. The law governing the matrimonial property regimes, or the property consequences of registered partnerships, has universal scope. This agreement in the form envisaged, which is backed by the need for legal certainty and predictability of the applicable rules, means that the spouses, in family problems which ha…

Depressive Symptoms Are Associated With Decreased Quality of Life and Work Ability in Currently Working Health Care Workers With Recurrent Low Back P…

2022

OBJECTIVE: This study investigates the association between depressive symptoms and multisite pain and health-related quality of life and work ability in currently employed health care workers with recurrent low back pain (LBP). METHODS: Multisite pain, depressive symptoms, quality of life, and work ability were assessed by validated questionnaires. A generalized linear model was used for statistical analysis. RESULTS: Notably, 28% of female health care workers with LBP had at least moderate levels of depressive symptoms. Depressive symptoms were significantly associated with decreased health-related quality of life and work ability. Multisite pain was not significantly associated with work …