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FMapper: Scalable read mapper based on succinct hash index on SunWay TaihuLight

2022

Abstract One of the most important application in bioinformatics is read mapping. With the rapidly increasing number of reads produced by next-generation sequencing (NGS) technology, there is a need for fast and efficient high-throughput read mappers. In this paper, we present FMapper – a highly scalable read mapper on the TaihuLight supercomputer optimized for its fourth-generation ShenWei many-core architecture (SW26010). In order to fully exploit the computational power of the SW26010, we employ dynamic scheduling of tasks, asynchronous I/O and data transfers and implement a vectorized version of the banded Myers algorithm tailored to the 256 bit vector registers of the SW26010. Our perf…

256-bitSpeedupXeonComputer Networks and CommunicationsComputer scienceHash functionParallel computingSW26010SupercomputerTheoretical Computer ScienceArtificial IntelligenceHardware and ArchitectureScalabilitySoftwareSunway TaihuLightJournal of Parallel and Distributed Computing
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