Search results for "25"

Social disadvantage and psychosis: a case control study on italian First-Episodes of Psychosis (FEP)

2014

Introduction: A growing body of literature suggests that people affected by psychotic disorders are more likely to be unemployed, tend to live alone, have a poor social network, and are not able to establish long-term relationships (Morgan et al., 2008). Aims: To investigate social disadvantage in a sample of first-episode of psychosis patients and geographically matched controls. Methods: The study sample consists of 52 healthy controls and 37 FEP who were assessed using the MRC Sociodemographic Schedules. Results: Preliminary results suggest that, consistently with the literature, cases are more exposed than controls to social disadvantage. They tend to reach a lower education degree (OR …

Searching for the truth about schizophrenia requires the application of similarly high standards of proof to biological and social risk factors

2013

In their provocative paper, Bentall and Varese (2012) criticize our review on child abuse and schizophrenia (Sideli, Mule, La Barbera, & Murray, 2012) and suggest that we have a biological bias whi...

Intra-Tumour Genetic Heterogeneity and Prognosis in High-Risk Neuroblastoma

2021

Simple Summary Neuroblastoma (NB) is the most common extra-cranial solid paediatric cancer and is responsible for 15% of childhood cancer deaths. Patients with NB are characterized by presenting a very heterogeneous clinic (inter-tumoural heterogeneity) and also both spatial and temporal intra-tumour heterogeneity (ITH) reflected in their genetic aberrations, which may be the consequence of the coexistence of different microenvironments within the tumour. Applying pangenomic techniques to detect genomic aberrations in different biopsies (solid and liquid) of high risk NB (HR-NB) we have detected spatial ITH in a surprisingly high percentage (almost 40%) of the studied cohort. Moreover, a po…

Improvement of the photo-stability of polystyrene-block-polybutadiene-block-polystyrene through carbon nanotubes

2015

Abstract The photo-stability of Polystyrene-Polybutadiene-Polystyrene (SBS) based nanocomposites containing bare multi-walled carbon nanotubes (CNTs) and carbon nanotubes bearing carboxylic functional groups (CNTs-COOH) in comparison to that of pristine SBS has been studied. The photo-oxidation of pristine SBS occurs through crosslinking reactions and oxidized species formation and both these processes begin at early stage of exposure. The formation of crosslinking, formerly in polybutadiene phase, assessed by spectroscopical (FTIR), mechanical, dynamic mechanical and rheological analysis, leads to occurrence of internal mechanical stresses in the solid state and the SBS samples become prem…

Defensa de D. Josef Antonio Sombiela y demas arrestados en la Ciudadela á la Exposicion de los Procuradores Síndicos

Text a 1 col Sign.: 1(4, 2(2). - El quadern 1 envolta el 2

Optimizing Sequential Systemic Therapies for Advanced Hepatocellular Carcinoma: A Decision Analysis

2020

Background: An optimal sequential systemic therapy for advanced hepatocellular carcinoma (HCC) has not been discovered. We developed a decision model based on available clinical trials to identify an optimal risk/benefit strategy for sequences of novel systemic agents. Methods: A Markov model was built to simulate overall survival (OS) among patients with advanced HCC. Three first-line (single-agent Sorafenib or Lenvatinib, and combination of Atezolizumab plus Bevacizumab) followed by five second-line treatments (Regorafenib, Cabozantinib, Ramucirumab, Nivolumab, Pembrolizumab) were compared in fifteen sequential strategies. The likelihood of transition between states (initial treatment, ca…

Application of conductometric and pH metric measurements in determining the kinetics and equilibrium parameters of the heterophasic ion exchange: Met…

2019

The application possibilities of conductometric and pH metric measurements in the description of the process of heterophasic ion exchange have been analysed, between metal cation (Zn, Cu) - proton, which occurs according to the formula, M+ + HR ⇄ H+ + MR, where R is an anion permanently bound in the sorbent. Kinetic models of the pseudo-first and pseudo-second order reactions, as well as the Langmuir isotherm model which describes the process equilibrium, have been used in mathematical presentations. It was confirmed that conductometric and pH metric measurements are equally effective in the assessment of such processes' parameters, in comparison with the expensive method of determining met…

Desde el hueco, la posmemoria

2019

CCDC 706487: Experimental Crystal Structure Determination

2009

Related Article: G.Podoprygorina, M.Bolte, V.Bohmer|2009|Org.Biomol.Chem.|7|1592|doi:10.1039/b819710e

CCDC 809075: Experimental Crystal Structure Determination

2011

Related Article: K.Raatikainen, J.Huuskonen, K.Rissanen|2011|Dalton Trans.|40|5706|doi:10.1039/c1dt10406c