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showing 10 items of 3263 documents
Entrevista a Nora Strejilevich
2019
Impact of Distressing Media Imagery on Children
2016
Children are particularly fragile and vulnerable to the impact of traumatic events or their mediated representation because they lack the skills and experience in the management of difficult information. Children have different concepts of health and disaster than adults and institutions, depending mainly on their cognitive, emotional, social, psychological, and physical development. If left alone with threatening messages, children are less able to fully understand the information to which they had been exposed. Therefore, they may fail to integrate the external data into their psychological schema of coping strategies. Children usually count on caregivers to deal with stressors, and they …
FEM analysis of push-out test response of Hybrid Steel Trussed Concrete Beams (HSTCBs)
2015
Abstract Aiming to investigate the steel truss–concrete stress transfer mechanism in Hybrid Steel Trussed–Concrete Beams (HSTCBs), a three-dimensional (3D) nonlinear Finite Element (FE) model is developed. The constitutive relationship of the steel composing the plates and the rebars is modeled by means of a quadri-linear law, while the concrete behavior is defined by means of a Concrete Damaged Plasticity (CDP) model, suitable for modeling concrete and brittle materials. Two main failure mechanisms are considered, namely the tensile cracking and the compressive crushing. In order to accurately grasp the complicate dowel and bond phenomena arising at the steel–concrete interface, a 3D solid…
Subdifferential and conjugate calculus of integral functions with and without qualification conditions
2023
We characterize the subdifferential and the Fenchel conjugate of convex integral functions by means of respectively the approximate subdifferential and the conjugate of the associated convex normal integrands. The results are stated in Suslin locally convex spaces, and do not require continuity-type qualification conditions on the functions, nor special topological or algebraic structures on the index set. Consequently, when confined to separable Banach spaces, the characterizations of such a subdifferential are obtained using only the exact subdifferential of the given integrand but at nearby points. We also provide some simplifications of our formulas when additional continuity conditions…
Efficient Analysis of Arbitrarily Shaped Inductive Obstacles in Rectangular Waveguides Using a Surface Integral Equation Formulation
2007
In this paper we propose to use the Surface Integral Equation technique for the analysis of arbitrarily shaped Hplane obstacles in rectangular waveguides, which can contain both metallic and/or dielectric objects. The Green functions are formulated using both spectral and spatial images series, whose convergence behavior has been improved through several acceleration techniques. Proceeding in this way, the convergence of the series is not attached to the employment of any particular basis or test function, thus consequently increasing the flexibility of the implemented technique. In order to test the accuracy and numerical efficiency of the proposed method, results for practical microwave c…
Assessment of particle suspension conditions in stirred vessels by means of pressure gauge technique
2002
In this work the quantitative assessment of the mass of suspended solid particles in stirred vessels is performed using the Pressure Gauge Technique. This is based on the measurements of the pressure increase on the tank bottom due to the presence of suspended solid particles at any agitation speed. The method has the advantages of not utilising visual observations and of easy and inexpensive application to both laboratory and industrial equipment. Very few data are available in literature and the experimental results collected using the present PGT technique and the correlations here proposed are of considerable academic and industrial interest.
Solubilized liver extracellular matrix maintains primary rat hepatocyte phenotype in-vitro.
2015
Whole organ engineering and cell-based regenerative medicine approaches are being investigated as potential therapeutic options for end-stage liver failure. However, a major challenge of these strategies is the loss of hepatic specific function after hepatocytes are removed from their native microenvironment. The objective of the present study was to determine if solubilized liver extracellular matrix (ECM), when used as a media supplement, can better maintain hepatocyte phenotype compared to type I collagen alone or solubilized ECM harvested from a non-liver tissue source. Liver extracellular matrix (LECM) from four different species was isolated via liver tissue decellularization, solubil…
T helper cell polarisation in coeliac disease: any (T-)bet ?
2004
Recent data strongly support the view that coeliac disease is a Th1 mediated inflammatory disease as both interferon γ production and T-bet levels in gut infiltrating cells are upregulated The puzzling observation on high interferon γ (IFN-γ) but low interleukin (IL)-12 levels in coeliac disease (CD) has resulted in questions about the underlying principles of T helper cell polarisation. In this issue of G ut ,1 the molecular basis of T helper cell polarisation in CD has been illuminated by the finding that T-bet, the master transcription factor of T helper cell type 1 (Th1) cells, is upregulated in this disease [see page 1090] . The past decade has witnessed a dramatic improvement in our p…
Unexpected Modulation of Recall B and T Cell Responses after Immunization with Rotavirus-like Particles in the Presence of LT-R192G
2010
LT-R192G, a mutant of the thermolabile enterotoxin of E. coli, is a potent adjuvant of immunization. Immune responses are generally analyzed at the end of protocols including at least 2 administrations, but rarely after a prime. To investigate this point, we compared B and T cell responses in mice after one and two intrarectal immunizations with 2/6 rotavirus-like particles (2/6-VLP) and LT-R192G. After a boost, we found, an unexpected lower B cell expansion measured by flow cytometry, despite a secondary antibody response. We then analyzed CD4(+)CD25(+)Foxp3(+) regulatory T cells (Tregs) and CD4(+)CD25(+)Foxp3(-) helper T cells after in vitro (re)stimulation of mesenteric lymph node cells …
Evidence for thermal equilibration in multifragmentation reactions probed with bremsstrahlung photons
2001
The production of nuclear bremsstrahlung photons (E$_{\gamma}>$ 30 MeV) has been studied in inclusive and exclusive measurements in four heavy-ion reactions at 60{\it A} MeV. The measured photon spectra, angular distributions and multiplicities indicate that a significant part of the hard-photons are emitted in secondary nucleon-nucleon collisions from a thermally equilibrated system. The observation of the thermal component in multi-fragment $^{36}$Ar+$^{197}$Au reactions suggests that the breakup of the thermalized source produced in this system occurs on a rather long time-scale.