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showing 10 items of 3263 documents
Performance of Contrast-Enhanced Ultrasound in Thyroid Nodules: Review of Current State and Future Perspectives
2021
Simple Summary Ultrasound has been used as baseline imaging for thyroid nodules for decades; nevertheless, no single feature is sensitive or specific enough to exclude or confirm thyroid malignancy. Therefore, clinical practice and research still focus on less invasive diagnostic patterns to reduce unnecessary fine-needle aspiration biopsies or surgery. The main advantage of CEUS is the ability to assess the sequence and intensity of vascular perfusion and hemodynamics in the thyroid nodule, thus providing real-time characterization of nodule features, and considered a valuable new approach in the determination of benign vs. malignant nodules. In addition, contrast agents used in CEUS can h…
OR18-01 Effect of Teprotumumab on Proptosis Reduction Across Various Demographic Sub-Groups
2020
Abstract Introduction: Teprotumumab, an insulin-like growth factor 1 receptor inhibitory monoclonal antibody, was recently shown to significantly reduce proptosis in patients with active, moderate-to-severe thyroid eye disease (TED) in phase 2 and phase 3 clinical trials.1,2 Prior analyses have demonstrated a combined trial proptosis response (≥2 mm reduction) rate of 77.4% in the teprotumumab group and 14.9% in the placebo group after 24 weeks of therapy (p < 0.001).3 The current analysis was performed to investigate whether or not patient demographic characteristics influence the teprotumumab proptosis response. Methods: Data from two 24-week randomized, double-masked, placebo-cont…
SAT-429 Systemic Safety Analysis of Mycophenolate in Graves’ Orbitopathy
2020
Abstract Context The dual antiproliferative mechanism of mycophenolate appears to be beneficial in Graves’ orbitopathy (GO). Methods The safety data, which is of utmost importance in immunomodulation, from the two major randomized mycophenolate trials [“Chinese trial” (1) and “European Group on Graves’ Orbitopathy (EUGOGO) trial” (2)] and the original database of the EUGOGO trial were systematically analyzed. Treatment efficacy stratified by individual visual parameters of clinical disease activity and severity were also compared. Results A total of 129 adverse events (AE) involving 50 patients (29.4%) were noted among all mycophenolate-treated patients. Mycophenolate sodium plus intravenou…
Synthesis of vanillin in water by TiO2 photocatalysis
2012
Abstract The photoproduction of vanillin is studied in aqueous medium starting from trans-ferulic acid, isoeugenol, eugenol or vanillyl alcohol by using both commercial and home prepared TiO2 samples as photocatalysts and batch Pyrex photoreactors. The photo-oxidation at room temperature of these compounds produces vanillin with a selectivity ranging from 1.4 to 21 mol% with respect to the converted substrate. An investigation on the intermediates was performed in the case of trans-ferulic acid; for this substrate the most important intermediates were homovanillic acid, vanillyl mandelic acid, trans-caffeic acid, formic acid, acetic acid, and oxalic acid. The carbon mass balance, including …
Una tabla inédita de Fernando Yáñez y nueva luz sobre su estancia en Almedina (1518-1525)
2020
The contribution presents a new acquisition for the catalog of Fernando Yáñez, a Holy Family dating back to 1523, shedding new light on the artist?s production in the third decade of the sixteenth century during his return to Almedina, his birthplace, in a time frame that divides the works for Valencia, like the retablo mayor for the city?s cathedral, from his altarpieces for Cuenca.
Tabula seu Index atque compendium, & epilogus omnium sententiarum Diui Thomae Aquinatis, per conclusiones resolutas ... / à ... fratre Petro Bergome…
1539
Sig. [creu grega]4, A-CCC8, a-q8. - Els 127 f. corresponen a: Concordantiae dictorum et conclusionum diui Thomae de Aquino... i Autoritates Sacrae Scripturae, quas Diuus Thomas de Aquino... atq[ue] in diuersis suis libris... diligentissime exposuit Capitals grav. Text a dos col. - Reclams al final de cada quadern. - Registre
In defensiones theologiae Thomae Aquinatis, sive In quaestiones J. Capreoli super IV libros Sententiarum compendium / per Silvestrum de Prierio, cum …
1497
Sig. [ ]4, a-n8, aa-kk8, ll4, mm4, A-C8, D6, E4, AA-DD8, EE-GG6, HH4, I4, [1]-[9]4. - Data d'impr. 15-28 abril, 1497 L. gòt. - 2 col. - 46 lín. - Esp. o min. p. inic. - Registre. - Capçaleres. - Fil.: corona
Controuersiarum theologicarum inter S. Thomam, et Scotum ... / Auctore ... Ioannes de Rada ... Ordinis S. Francisci Regulari Obseruantia ...
1604
Sig. +-+++4, A-Ll8, Mm7 Port. a dues tintes. - text a dues col. - Errates en la pag.
Rithmus in laudem D. Thomae Aquinatis doctoris angelici
1750
El full orlat Grav. xil. enmarcat del sant Text del goig a tres col. separades per bandes
Loores al angélico doctor Santo Thomas de Aquino
1750
El full orlat Grav. xil. enmarcat del sant, flanquejat per gerros amb flors Text del goig a tres col. separades per bandes