Search results for "25"

Glutathione in Cancer Cell Death

2011

Glutathione (L-γ-glutamyl-L-cysteinyl-glycine; GSH) in cancer cells is particularly relevant in the regulation of carcinogenic mechanisms; sensitivity against cytotoxic drugs, ionizing radiations, and some cytokines; DNA synthesis; and cell proliferation and death. The intracellular thiol redox state (controlled by GSH) is one of the endogenous effectors involved in regulating the mitochondrial permeability transition pore complex and, in consequence, thiol oxidation can be a causal factor in the mitochondrion-based mechanism that leads to cell death. Nevertheless GSH depletion is a common feature not only of apoptosis but also of other types of cell death. Indeed rates of GSH synthesis and…

Propiedades psicométricas del cuestionario de afronta¬miento al estrés para pacientes oncológicos (CAEPO)

2017

Los objetivos del estudio fueron: 1) analizar la estructura factorial de la escala CAEPO mediante análisis factorial exploratorio y confirmatorio; 2) estimar la consistencia interna de los factores; 3) describir la distribución de los factores; 4) analizar las diferencias de medias de las estrategias de afrontamiento entre hombres y mujeres. El Cuestionario de Afrontamiento al Estrés para Pacientes Oncológicos (CAEPO) de González (2004) fue aplicado a 148 pacientes oncológicos. Se sugiere reducir la escala a 35 ítems. Se encontró una estructura de cuatro factores correlacionados con consistencias internas de adecuadas a altas. La distribución de los factores se ajustó a una curva normal y n…

Tempo and mode of early gene loss in endosymbiotic bacteria from insects

2006

Abstract Background Understanding evolutionary processes that drive genome reduction requires determining the tempo (rate) and the mode (size and types of deletions) of gene losses. In this study, we analysed five endosymbiotic genome sequences of the gamma-proteobacteria (three different Buchnera aphidicola strains, Wigglesworthia glossinidia, Blochmannia floridanus) to test if gene loss could be driven by the selective importance of genes. We used a parsimony method to reconstruct a minimal ancestral genome of insect endosymbionts and quantified gene loss along the branches of the phylogenetic tree. To evaluate the selective or functional importance of genes, we used a parameter that meas…

Cyber droghe e binaural beats: gli stati non convenzionali di coscienza nell’era delle tecnologie digitali

2008

Decoupled Acoustic and Visual Components in the Multimodal Signals of the Common Cuckoo (Cuculus canorus)

2021

Because of its parasitic habits, reproduction costs of the common cuckoo (Cuculus canorus) are mostly spent in pre-laying activities. Female costs are limited to searching host nests and laying eggs, whereas, males spend time in performing intense vocal displays, possibly with territorial purpose. This last aspect, together with a sexual plumage dimorphism, points to both intra- and inter-sexual selections operating within this species. One element triggering sexual selection is a differential fitness accrued by different phenotypes. Before analyzing possible sexual selection mechanisms operating in cuckoos, it is therefore necessary to verify whether there is a variability among male secon…

New Polylactic Acid Composites Reinforced with Artichoke Fibers

2015

In this work, artichoke fibers were used for the first time to prepare poly(lactic acid) (PLA)-based biocomposites. In particular, two PLA/artichoke composites with the same fiber loading (10% w/w) were prepared by the film-stacking method: the first one (UNID) reinforced with unidirectional long artichoke fibers, the second one (RANDOM) reinforced by randomly-oriented long artichoke fibers. Both composites were mechanically characterized in tensile mode by quasi-static and dynamic mechanical tests. The morphology of the fracture surfaces was analyzed through scanning electron microscopy (SEM). Moreover, a theoretical model, i.e., Hill's method, was used to fit the experimental Young's modu…

Rickettsiae of the spotted fever group in dog fleas (Ctenocephalides spp.) in Western Sicily

1989

Anerkjennelse og menneskeverdets forankring : henimot en transnasjonal anerkjennelsespolitikk

2011

Anerkjennelse spiller en nøkkelrolle for menneskeverdet innenfor Frankfurterskolens kritiske teori. Men hvorledes skal «anerkjennelse» forstås? Og hvorledes kan anerkjennelse innløse menneskeverdets universelle og egalitære fordring? Jürgen Habermas' og Axel Honneths «familiekrangel» bidrar med relevant innsikt om relasjonen mellom menneskeverd og anerkjennelse. Dette er en innsikt med affinitet til menneskeverdets normative legitimering i dagens transnasjonaliserte verden.Nøkkelord: Menneskeverd, transnasjonal anerkjennelsespolitikk, Jürgen Habermas, Axel HonnethEnglish summary: Recognition and the Grounding of Human Dignity – Towards a Transnational Politics of RecognitionRecognition play…

Oxygen transfer performance of unbaffled stirred vessels in view of their use as biochemical reactors for animal cell growth

2012

Cultivation of microorganisms, plants or animal cells requires liquid agitation in order to ensure oxygen and nutrient transfer and to maintain cell suspension. However, In such suspensions both mechanical agitation and sparging aeration can cause cell death. Many studies on animal cell damage due to mechanical agitation and sparging aeration have shown that mechanical damage of freely suspended animal cells is in most cases associated with bursting bubbles at the air–liquid interface (Barrett et al., 2010, Nienow et al., 1996). Gas bubbles are usually generated by direct air sparging to propagate oxygen in a culture suspension. Mechanical agitation may also introduce gas bubbles to the cul…

Technologies for cultivation and exploitation of microalgae in industrial applications

2020

This thesis work is focused on technologies for the development of the microalgal industry. During this 3-years PhD work several themes were addressed. Section 1 consists in a literature review concerning the general features of microalgae, their composition and a description of the photosynthetic process. Furthermore, themes such as biosynthetic pathways, growth kinetics, microalgae cultivation and their applications are reviewed. Section 2 focuses on the genetic manipulation of microalgae aimed at producing a vitamin B12-enriched food supplement. In this case, the human intrinsic factor gene, was inserted in the genome of the microalgae Chlamydomonas reinardhtii in order to integrate new …