Search results for "26"

The shape of the liquid plain: sicilian salt flats

2019

This paper analyzes the salt flats as a place for the mixing of knowledge and experiences that originate and substantiate life: from the application of physical, chemical and biological principles to produce salt, to economic laws to regulate sales and trade, to aspects socio-anthropological aspects underlying the life of the communities that worked in production. A patrimony of material and immaterial overlaps, generated by the redesign of a segment of territory with physical and positional characteristics median between sea and land, and in which man strives to obtain fundamental resources for his livelihood. Given the complex moment of crisis and gradual abandonment that these particular…

PECULIARE EVOLUZIONE DELLA SEMEIOTICA NEURORADIOLOGICA DI UN CASO DI MALATTIA DEMIELINIZZANTE CON LESIONI PSEUDOTUMORALI

2013

SCOPO DEL LAVORO Presentiamo un caso di una paziente di 24 anni che giunge alla nostra attenzione per la comparsa di disartria come quadro clinico d’esordio di una forma aggressiva di malattia demielinizzante di cui si valuta l’atipica evoluzione neuroradiologica delle lesioni pseudotumorali che la caratterizzano e le possibili diagnosi differenziali. MATERIALI E METODI La paziente dopo una prima valutazione in PS è stata sottoposta a TC encefalo, ricoverata presso l’U.O. di Neurologia, sottoposta a controlli RM seriati (anche con tecniche avanzate); durante la degenza è stata inoltre effettuata una biopsia stereotassica. RISULTATI La TC ha rilevato almeno tre lesioni ipodense: a sinistra…

An Examination of the Relationship Between Coaches’ Transformational Leadership and Athletes’ Personal and Group Characteristics in Elite Youth Soccer

2021

There is a growing body of the literature highlighting the positive impact of transformational leadership behaviours across contexts, including sport. However, there is a lack of knowledge of this relationship within elite sport settings. Thus, the purpose of the present study was to examine the relationship between elite youth athletes’ perceptions of coaches’ transformational coaching-behaviours and variables that have been linked to transformational leadership in other settings (i.e., group cohesion, motivational climate, self-regulation of learning and athlete satisfaction). Norwegian elite youth soccer players (n= 753) selected into the national talent development program completed que…

Sport participation and loneliness in adolescents: the mediating role of perceived social competence

2013

Published version of an article in the journal: Current Psychology. Also available from the publisher at: http://dx.doi.org/10.1007/s12144-013-9174-5 Young people perceive loneliness as a distressing emotional experience associated with sadness and boredom. Also, feelings of loneliness may be associated with psychosocial and emotional problems during adolescence. The aim of this study was to investigate whether perceived social competence mediated the cross-sectional relationship between sport participation and loneliness in young people when controlling for age, sex, shyness, and non-organized physical activity. This cross-sectional study consisted of 2,055 pupils (995 boys and 1,060 girls…

Sequenziamento temporale ed elaborazione neurale: una prospettiva psicofisiologica

2011

Effects of BRCA2 cis-regulation in normal breast and cancer risk amongst BRCA2 mutation carriers

2012

<p>Introduction: Cis-acting regulatory single nucleotide polymorphisms (SNPs) at specific loci may modulate penetrance of germline mutations at the same loci by introducing different levels of expression of the wild-type allele. We have previously reported that BRCA2 shows differential allelic expression and we hypothesize that the known variable penetrance of BRCA2 mutations might be associated with this mechanism.</p>\ud \ud <p>Methods: We combined haplotype analysis and differential allelic expression of BRCA2 in breast tissue to identify expression haplotypes and candidate cis-regulatory variants. These candidate variants underwent selection based on in silico predicti…

Microneedle-Based Delivery: An Overview of Current Applications and Trends

2020

Microneedle arrays (MNA) are considered as one of the most promising resources to achieve systemic effects by transdermal delivery of drugs. They are designed as a minimally invasive, painless system which can bypass the stratum corneum, overcoming the potential drawbacks of subcutaneous injections and other transdermal delivery systems such as chemical enhancers, nano and microparticles, or physical treatments. As a trendy field in pharmaceutical and biomedical research, its applications are constantly evolving, even though they are based on very well-established techniques. The number of molecules administered by MNA are also increasing, with insulin and vaccines administration being the …

Psychometric Properties of the Scoliosis Research Society Questionnaire (Version 22r) Domains Among Adults With Spinal Deformity : A Rasch Measuremen…

2022

Objective: Adults with degenerative spinal deformity (ASD) have lower health-related quality of life (HRQL) compared to the general population. Applying Rasch Measurement Theory (RMT), this study tested the revised Scoliosis Research Society-22 (SRS-22r) HRQL instrument among symptomatic adult patients with degenerative spinal disorders and varying degrees of ASD. Methods: SRS-22r data from 637 outpatient spine clinic patients with degenerative spine conditions were investigated for unidimensionality, item/scale fit, differential item functioning (DIF), scale coverage/targeting, and person separation index (PSI) using RMT. Results: Unidimensionality of the SRS-22r was not supported for eith…

Sulla legittimazione del socio non amministratore ad esercitare l'azione di responsabilità sociale contro gli amministratori delle società di persone

2021

Advances in Nanoliposomes Production for Ferrous Sulfate Delivery

2020

In this study, a continuous bench scale apparatus based on microfluidic fluid dynamic principles was used in the production of ferrous sulfate-nanoliposomes for pharmaceutical/nutraceutical applications, optimizing their formulation with respect to the products already present on the market. After an evaluation of its fluid dynamic nature, the simil-microfluidic (SMF) apparatus was first used to study the effects of the adopted process parameters on vesicles dimensional features by using ultrasonic energy to enhance liposomes homogenization. Subsequently, iron-nanoliposomes were produced at different weight ratios of ferrous sulfate to the total formulation components (0.06, 0.035, 0.02, an…