Search results for "2708"

showing 10 items of 30 documents

Chemical Composition of the Essential Oil of Bupleurum Fontanesii (Apiaceae) Growing Wild in Sicily and its Activity on Microorganisms Affecting Hist…

2016

Hydrodistillation of the flowers (BpFl) of and fruits (BpFr) of Bupleurum fontanesii Guss. ex Caruel gave two oils that were analyzed by GC and GC-MS. The main components were α-elemol (16.7%), caryophyllene oxide (16.4%) and heptacosane (15.9%) in BpFl, and spathulenol (16.8%), caryophylladienol I (13.2%) and α-elemol (12.8%) in BpFr. A good antimicrobial activity against several microorganisms, including Bacillus subtilis, Staphylococcus aureus, Fusarium oxysporum and Aspergillus niger, all infesting historical art craft, was also determined.

α-ElemolBupleurumAntifungal AgentsMicroorganismPlant ScienceBacillus subtilis01 natural scienceslaw.inventionlawVolatile componentDrug DiscoveryBotanyFusarium oxysporumOils VolatilePlant OilsSicilyEssential oilPharmacologyApiaceaeBacteriaBupleurum fontanesiibiology010405 organic chemistryDrug Discovery3003 Pharmaceutical ScienceAspergillus nigerFungiSpathulenolfood and beveragesGeneral MedicineComplementary and Alternative Medicine2708 DermatologyAntimicrobialbiology.organism_classificationAnti-Bacterial AgentsBupleurum0104 chemical sciences010404 medicinal & biomolecular chemistryCaryophyllene oxideComplementary and alternative medicineArtApiaceaeNatural Product Communications
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Anti-cytokine therapy for prevention of atherosclerosis

2015

Abstract Background Currently a chronic inflammation is considered to be the one of the most important reasons of the atherosclerosis progression. A huge amount of researches over the past few decades are devoted to study the various mechanisms of inflammation in the development of atherosclerotic lesions. Purpose To review current capabilities of anti-inflammatory therapy for the prevention and treatment of atherosclerosis and its clinical manifestations. Methods Appropriate articles on inflammatory cytokines in atherosclerosis and anti-inflammatory prevention of atherosclerosis were searched in PubMed Database from their respective inceptions until October 2015. Sections “The role of infl…

Male0301 basic medicine3003Anti-Inflammatory AgentsPharmaceutical ScienceInflammation030204 cardiovascular system & hematologyBioinformaticsProinflammatory cytokineAnti-Cytokine TherapyDouble blind03 medical and health sciences0302 clinical medicineDouble-Blind MethodDrug DiscoverymedicineAnimalsHumansInterleukin 6InflammationPharmacologybiologyTraditional medicinebusiness.industryMedicine (all)Drug Discovery3003 Pharmaceutical ScienceAtherosclerosisComplementary and Alternative Medicine2708 DermatologyHerbal preparationClinical trial030104 developmental biologyComplementary and alternative medicineAtherosclerosis preventionDisease Progressionbiology.proteinCytokinesHerbal preparationsAtherosclerosis preventionMolecular MedicinePlant Preparationsmedicine.symptomAnti-cytokine therapybusiness
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Chemical Composition and Antimicrobial Activity of the Essential Oil from Flowers of Eryngium triquetrum (Apiaceae) Collected Wild in Sicily

2016

The chemical composition of the essential oil from flowers of Eringium triquetrum Vahl. collected in Sicily was evaluated by GC and GC-MS. The main components were pulegone (50.6%), piperitenone (30.5%) and menthone (7.0%). Comparison of this oil with other studied oils of Eringium species is discussed. The oil showed good antibacterial and antifungal activities against some microorganisms that infest historical art works.

EryngiumFlowersPlant Science01 natural scienceslaw.inventionchemistry.chemical_compoundAnti-Infective AgentslawPulegoneVolatile componentDrug DiscoveryBotanyOils VolatilePlant OilsEryngium triquetrumPiperitenoneSettore BIO/15 - Biologia FarmaceuticaSicilyChemical compositionEssential oilPharmacologyApiaceaeBacteriabiology010405 organic chemistryMenthone.Drug Discovery3003 Pharmaceutical ScienceFungiSettore CHIM/06 - Chimica OrganicaGeneral MedicineComplementary and Alternative Medicine2708 Dermatologybiology.organism_classificationAntimicrobialEryngium triquetrumMenthone0104 chemical sciences010404 medicinal & biomolecular chemistryComplementary and alternative medicinechemistryTriquetrumPulegoneApiaceaeNatural Product Communications
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Chemical Composition of the Essential Oil of Mentha pulegium Growing Wild in Sicily and its Activity on Microorganisms Affecting Historical Art Crafts

2017

The chemical composition of the essential oil from aerial parts of Mentha pulegium L. (Linné) collected in Sicily was evaluated by GC and GC-MS. The main components were pulegone (50.6%), piperitenone (27.8%) and menthone (6.9%). Comparison of this oil with other studied oils of different populations is discussed. The oil showed good antibacterial and antifungal activities against some microorganisms that infest historical art works.

Plant compositionMicroorganismPlant ScienceMenthone01 natural scienceslaw.inventionchemistry.chemical_compound0404 agricultural biotechnologylawMentha pulegiumPulegoneVolatile componentDrug DiscoveryBotanyPiperitenoneChemical compositionEssential oilPharmacologyLamiaceaebiologyDrug Discovery3003 Pharmaceutical Science04 agricultural and veterinary sciencesGeneral MedicineComplementary and Alternative Medicine2708 Dermatologybiology.organism_classification040401 food scienceMenthone0104 chemical sciences010404 medicinal & biomolecular chemistryComplementary and alternative medicinechemistryLamiaceaeMentha pulegiumPulegoneNatural Product Communications
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Population-based case-control study of essential tremor.

1998

Current epidemiologic data on the association between environmental factors and essential tremor (ET) are scanty. In a population-based case-control study we investigated the relationship between some putative risk factors and ET. In the present study, we included all subjects identified during a door-to-door prevalence survey in a Sicilian community, affected by ET, and alive on 1 November 1987 (n=31). Of the 31 prevalent cases of ET, we were able to contact 28 subjects. Twenty-eight controls were randomly selected from the general population and matched to each case for age and sex. Exposure variables were investigated by interviewing the patients and their controls or close relatives, us…

AdultMalemedicine.medical_specialtyPathologyEpidemiologyEssential TremorPopulationDermatologyPopulation basedOddsRisk FactorsEpidemiologymedicinePrevalenceHumanseducationAgedAged 80 and overeducation.field_of_studyNeuroscience (all)Essential tremorbusiness.industryGeneral NeuroscienceCase-control studyCase-control studyGeneral MedicineEnvironmental exposureEnvironmental ExposureMiddle Agedmedicine.diseasePsychiatry and Mental healthCase-Control StudiesSettore MED/26 - NeurologiaFemaleNeurology (clinical)Epidemiologic databusiness2708DemographyItalian journal of neurological sciences
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Stroke incidence and survival in three Sicilian municipalities

1998

We investigated the incidence of first-ever stroke in three Sicilian municipalities over the years 1984–1987. Case ascertainment involved two approaches: a doorto-door two-phase prevalence survey and a study of death certificates. Only first-ever strokes occurring within the study time interval were included, and diagnoses were based on specified criteria. We found 138 subjects who had experienced a first stroke over 73 488 person-years; the average incidence rate (new cases per 1000 population per year) was 1.9 overall, 1.7 in men, and 2.1 in women. Incidence increased steeply with age and was similar in men and women. Incidence was similar in the three study municipalities. The overall ca…

medicine.medical_specialtyPediatricsNeurologySurvivalEpidemiologyPopulationEpidemiologyMedicineeducationSicilyStrokeNeuroradiologyeducation.field_of_studyNeuroscience (all)business.industryIncidenceGeneral NeuroscienceIncidence (epidemiology)medicine.diseaselanguage.human_languageStrokeItalyPsychiatry and Mental HealthlanguageSettore MED/26 - NeurologiaNeurology (clinical)businessStroke incidenceSicilian2708
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Resistance to water and abrasion of a broad-spectrum sunscreen: a prospective, open-label study.

2015

1303 BiochemistryFrictionAbrasion (mechanical)Ultraviolet RaysDrug Evaluation PreclinicalSunburn610 Medicine & healthSunscreening AgentsDermatologyAdministration Cutaneous030226 pharmacology & pharmacyBiochemistry2708 Dermatology03 medical and health sciencesBroad spectrum0404 agricultural biotechnology0302 clinical medicineOpen label study1312 Molecular BiologymedicineHumansProspective StudiesSunburnComposite materialMolecular BiologySkin damageSkinWater resistanceChemistry10177 Dermatology ClinicWater04 agricultural and veterinary sciencesmedicine.disease040401 food scienceLiposomesHydrophobic and Hydrophilic InteractionsSunscreening AgentsExperimental dermatology
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Indicaxanthin from Opuntia Ficus Indica (L. Mill) impairs melanoma cell proliferation, invasiveness, and tumor progression.

2018

Abstract Background: A strong, reciprocal crosstalk between inflammation and melanoma has rigorously been demonstrated in recent years, showing how crucial is a pro-inflammatory microenvironment to drive therapy resistance and metastasis. Purpose: We investigated on the effects of Indicaxanthin, a novel, anti-inflammatory and bioavailable phytochemical from Opuntia Ficus Indica fruits, against human melanoma both in vitro and in vivo. Study Design and Methods: The effects of indicaxanthin were evaluated against the proliferation of A375 human melanoma cell line and in a mice model of cutaneous melanoma. Cell proliferation was assessed by MTT assay, apoptosis by Annexin V-Fluorescein Isothio…

0301 basic medicine3003MaleSkin NeoplasmsPyridinesPyridinePhytochemicalsMelanoma ExperimentalPharmaceutical ScienceIndicaxanthinApoptosisBcl-2 B cell lymphoma gene-2 (Bcl-2)chemistry.chemical_compoundMice0302 clinical medicineOpuntia Ficus Indica (L.Mill)Settore BIO/10 - BiochimicaDrug DiscoveryCXCL1 chemokine (C-X-C motif) ligand 1MelanomaNF-κB nuclear factor kappa BMTT 3-[45-dimethyltiazol-2-yl]-25-diphenyl tetrazolium bromideMelanomaNF-kappa BOpuntiaComplementary and Alternative Medicine2708 DermatologyBetaxanthinsCXCL1030220 oncology & carcinogenesisMolecular MedicinePhC phytochemicalGrowth inhibitionIndicaxanthinHumanBiologyPhytochemicalNHEM normal human epidermal melanocyte03 medical and health sciencesc-FLIP FLICE-inhibitory proteinIn vivoCell Line TumormedicineAnimalsHumansNeoplasm InvasivenessSkin NeoplasmCell ProliferationNeoplasm InvasiveneInflammationPharmacologyCell growthAnimalDrug Discovery3003 Pharmaceutical ScienceApoptosimedicine.diseaseMice Inbred C57BL030104 developmental biologyComplementary and alternative medicinechemistryTumor progressionList of Abbrevations: AxV-FITC annexin V-fluorescein isothiocyanateBetaxanthinFruitCutaneous melanomaCancer researchPI propidium iodide PIPhytomedicine : international journal of phytotherapy and phytopharmacology
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A cross-sectional, multicentre study of the therapeutic management of multiple sclerosis relapses in Italy.

2013

Despite the existence of therapeutic guidelines, management of multiple sclerosis relapse remains heterogeneous. Optimisation of relapse outcome demands an improved understanding of the neurologist's therapeutic attitude towards relapse management, which is the aim of this study. Neurologists from 13 multiple sclerosis centres completed a questionnaire every time they assessed multiple sclerosis relapses. The questionnaire requested a guided description of the relapse's clinical characteristics and an indication of the prescribed therapy, supported with up to 3 out of 20 suggested reasons. Over 3 months, 368 questionnaires were collected. Median percentage (%) of 21 relapses resulting in a …

MalePediatricsNeurologyCross-sectional studymulti center studyAdrenal Cortex HormoneAdrenal Cortex HormonesRecurrenceSurveys and QuestionnairesMultiple SclerosiCorticosteroidSurveys and QuestionnaireRelapseSurveyNeuroradiologyGeneral MedicineMiddle AgedManagementPsychiatry and Mental healthMethylprednisoloneItalyNeurologyPsychiatry and Mental Healthmultiple sclerosiSettore MED/26 - NeurologiaFemaleNeurosurgerymedicine.drugHumanAdultmedicine.medical_specialtyMultiple SclerosisDermatologyMethylprednisolonemedicineHumansMedical prescriptionCross-Sectional Studietherapybusiness.industryMultiple sclerosismedicine.diseaseManagement of multiple sclerosisCross-Sectional StudiesHealth Care SurveyHealth Care SurveysPhysical therapyNeurology (clinical)business2708
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Italian Frontotemporal Dementia Network (FTD Group-SINDEM): sharing clinical and diagnostic procedures in Frontotemporal Dementia in Italy.

2014

In the prospect of improved disease management and future clinical trials in Frontotemporal Dementia, it is desirable to share common diagnostic procedures. To this aim, the Italian FTD Network, under the aegis of the Italian Neurological Society for Dementia, has been established. Currently, 85 Italian Centers involved in dementia care are part of the network. Each Center completed a questionnaire on the local clinical procedures, focused on (1) clinical assessment, (2) use of neuroimaging and genetics; (3) support for patients and caregivers; (4) an opinion about the prevalence of FTD. The analyses of the results documented a comprehensive clinical and instrumental approach to FTD patient…

CounselingMalemedicine.medical_specialtyNeurologyNetworkCounseling; Frontotemporal dementia; Frontotemporal lobar degeneration; Genetics; Network; Survey; Aged; Aged 80 and over; Caregivers; Female; Frontotemporal Dementia; Humans; Italy; Male; Prevalence; Community Networks; Information Dissemination; Medicine (all); 2708; Neurology (clinical); Psychiatry and Mental HealthDermatologyFrontotemporal lobar degenerationCommunity Networksddc:616.89Caregivers/psychologyCounseling; Frontotemporal dementia; Frontotemporal lobar degeneration; Genetics; Network; Survey; Aged; Aged 80 and over; Caregivers; Female; Frontotemporal Dementia; Humans; Italy; Male; Prevalence; Community Networks; Information Dissemination; 2708; Neurology (clinical); Psychiatry and Mental HealthEpidemiologymental disordersmedicineGenetics80 and overPrevalenceDementiaHumansDisease management (health)PsychiatrySurveyAgedMED/26 - NEUROLOGIAAged 80 and overItalian networkFRONTO Temporal dementiabusiness.industryInformation DisseminationMedicine (all)Frontotemporal dementia Frontotemporal lobar degeneration Network Survey Genetics CounselingGeneral MedicineFrontotemporal lobar degenerationFrontotemporal Dementia/diagnosis/epidemiologymedicine.diseaseClinical trialCaregiversItalyPsychiatry and Mental HealthFrontotemporal DementiaSettore MED/26 - NeurologiaFemaleNeurosurgeryNeurology (clinical)businessAged; Aged 80 and over; Caregivers; Female; Frontotemporal Dementia; Humans; Italy; Male; Prevalence; Community Networks; Information DisseminationFrontotemporal dementia2708Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
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