Search results for "28"

Study of oral microbiota and diet as casual factors of Black Stains in the pediatric patient

2019

The aim of the following study is to identify and quantify microorganisms in the saliva of black stain patients using species-specific probes for Actinomyces israelii, Actinomyces naeslundii, Streptococcus mutans and Lactobacillus spp, as well as a universal probe for bacterial 16S rDNA, to obtain the figure of the total bacterial counts (for test and control group). This study represents a first phase of the research line on extrinsic tooth pigmentation on developmental age patients. Materials and methods. The selected sample is composed of 20 subjects aged between 2 and 15 years and in good general and oral health among the patients included in a dental examination trial at the Department…

PRELIMINARY ANALYSES FROM A HOSPITAL BASED STUDY ON 3154 WESTERN SICILIAN PATIENTS WITH ORAL MUCOSAL LESIONS

2010

Objectives: Diagnosis of the wide variety of lesions that occur in the oral cavity is an essential part of dental practice. The objective of this study was to explore the demographic and behavioural profiles of patients affected by oral cavity diseases on a wide spectrum. Methods: Demographic and behavioural data of 3154 patients with at least one oral cavity disease among those consecutively visited between 2004 and 2009 at the Unit of Oral Medicine, were recorded: gender, age, smoking status, alcohol consumption, drugs use. Analysis was restricted to the eleven more frequent oral cavity diseases. Firstly, Multiple Correspondence Analysis (MCA) was applied as a descriptive tool to geometri…

Long-standing oral ulcers: proposal for a new 'S-C-D classification system': Authors' reply

2010

A strange “butterly-like” ulcer of the palate. May be it the results of an underlying trombotic event in a predisposed patient?

2013

Liminaalitilan käsite työn muutosten jäsentäjänä

2013

Liminaalitila on antropologiassa määritelty välitilaksi, kynnyksellä olemiseksi. Liminaalisuus on nykypäivän työelämälle ominainen piirre, joka voi näyttäytyä kaaoksena, mutta myös uutta luovana muutosvaiheena.

Intrinsic Lipschitz Graphs and Vertical β-Numbers in the Heisenberg Group

2016

The purpose of this paper is to introduce and study some basic concepts of quantitative rectifiability in the first Heisenberg group $\mathbb{H}$. In particular, we aim to demonstrate that new phenomena arise compared to the Euclidean theory, founded by G. David and S. Semmes in the 90's. The theory in $\mathbb{H}$ has an apparent connection to certain nonlinear PDEs, which do not play a role with similar questions in $\mathbb{R}^{3}$. Our main object of study are the intrinsic Lipschitz graphs in $\mathbb{H}$, introduced by B. Franchi, R. Serapioni and F. Serra Cassano in 2006. We claim that these $3$-dimensional sets in $\mathbb{H}$, if any, deserve to be called quantitatively $3$-rectifi…

Epidemiology, clinical manifestations, risk-reduction and treatment strategies of jaw osteonecrosis in cancer patients exposed to antiresorptive agen…

2014

Osteonecrosis of the jaws (ONJ) is an adverse side event of bisphosphonates and denosumab, antiresorptive agents that effectively reduce the incidence of skeletal-related events in patients with metastatic bone cancer and multiple myeloma. Available data suggest that 0–27.5% of individuals exposed to antiresorptive agents can develop ONJ. There is increasing evidence that avoidance of surgical trauma and infection to the jawbones can minimize the risk of ONJ, but there are still a significant number of individuals who develop ONJ in the absence of these risk factors. Bone necrosis is almost irreversible and there is no definitive cure for ONJ with the exclusion, in certain cases, of surgica…

Genetic profile and immunohistochemical study of clear cell renal carcinoma: Pathological-anatomical correlation and prognosis.

2021

Abstract Introduction Renal cell carcinoma (RCC) accounts for 2–3% of all tumors being the most frequent solid lesion in the kidney. Objective To determine what genetic alterations and immunohistochemical (IHC) of clear cell renal carcinoma (ccRCC) are associated with prognosis and tumor aggressiveness. Patients and Methods Experimental analytical study with 57 patients who underwent radical and partial nephrectomy between 2005 and 2011, all with diagnosis of ccRCC and minimum post-operative follow-up of 36 months. The pathological study included IHC determination of biomarkers associated (CAIX, CAM 5.2, CD10, c-erbB-2, EGFR, HIF-1a, Ki67, MDM2, PAX-2 y 8, p53, survivin and VEGFR 1 and 2). …

Molecular mechanisms of MYCN-dependent apoptosis and the MDM2-p53 pathway: an Achille’s heel to be exploited for the therapy of MYCN amplified neurob…

2012

The p53 oncosuppressor is very seldom mutated in neuroblastoma, but several mecha- nisms cooperate to its functional inactivation in this tumor. Increased MDM2 levels, due to genetic amplification or constitutive inhibition of p14ARF, significantly contribute to this event highlighting p53 reactivation as an attractive perspective for neuroblastoma treat- ment. In addition to its role in tumorigenesis, MYCN sensitizes untransformed and cancer cells to apoptosis. This is associated to a fine modulation of the MDM2-p53 pathway Indeed MYCN induces p53 and MDM2 transcription, and, by evoking a DNA damage response (DDR), it stabilizes p53 and its proapoptotic kinase Homeodomain Interacting Prote…

Perspectivas actuales de la filosofía y la pedagogía del deporte

2016

La filosofía del deporte, al igual que la pedagogía, la historia y otros estudios humanísticos alrededor del fenómeno deportivo, ha permanecido tradicionalmente en un segundo plano en facultades e instituciones educativas, incluso en aquellas cuyo fin es, precisamente, comprender adecuadamente cómo y por qué jugamos del modo que lo hacemos y con qué finalidades (Kretchmar, 2005). En una reciente editorial de la revista Sport, Ethics and Philosophy, Michael McNamee (2015) hace un repaso de la actualidad, exponiendo cómo a pesar de que la disciplina no para de crecer y ganar protagonismo, sobre todo en el ámbito editorial, no acaba de hacerse el hueco pertinente en la academia. Por otro lado,…