Search results for "29.0"
showing 10 items of 109 documents
Effect of LIF-withdrawal on acetylcholine synthesis in the embryonic stem cell line CGR8 is not mediated by STAT3, PI3Ks or cAMP/PKA pathways.
2015
Acetylcholine (ACh) acts as a local cellular signaling molecule and is widely expressed in nature, including mammalian cells and embryonic stem cells. The murine embryonic stem cell line CGR8 synthesizes and releases substantial amounts of ACh. Particularly during early differentiation - a period associated with multiple alterations in geno-/phenotype functions - synthesis and release of ACh are increased by 10-fold. In murine stem cells second messengers of the STAT-3, PI3K and cAMP/PKA pathways are involved in maintaining self-renewal and pluripotency. The present experiments were designed to test whether blockers of these signaling pathways enhance ACh cell content in the presence of LIF…
Parental Stress and Parental Ratings of Behavioral Problems of Enuretic Children.
2019
Background: Primary monosymptomatic nocturnal enuresis (PMNE) may have a stressful impact on the everyday life of children and parents, and it may represent a cumulative stress factor increasing feelings of "learned helplessness." Methods: The current study investigated parental stress in a group of parents (n = 330) of children affected by PMNE, compared to a group of parents (n = 330) of typical developing children (TDC). In addition, the study evaluated whether parents of PMNE children experience more emotional, social, and behavioral problems in their children, compared to parents of TDC. Finally, the study correlated frequency of enuresis with stress values and Child Behavior Checklist…
TRAIL-induced apoptosis of hepatocellular carcinoma cells is augmented by targeted therapies
2009
AIM: To analyze the effect of chemotherapeutic drugs and specific kinase inhibitors, in combination with the death receptor ligand tumor necrosis factor-related apoptosis inducing ligand (TRAIL), on overcoming TRAIL resistance in hepatocellular carcinoma (HCC) and to study the efficacy of agonistic TRAIL antibodies, as well as the commitment of antiapoptotic BCL-2 proteins, in TRAIL-induced apoptosis. METHODS: Surface expression of TRAIL receptors (TRAIL-R1-4) and expression levels of the antiapoptotic BCL-2 proteins MCL-1 and BCL-xL were analyzed by flow cytometry and Western blotting, respectively. Knock-down of MCL-1 and BCL-xL was performed by transfecting specific small interfering RNA…
CCDC 1826427: Experimental Crystal Structure Determination
2018
Related Article: Jie‐Shun Cui, Qian‐Kai Ba, Hua Ke, Arto Valkonen, Kari Rissanen, Wei Jiang|2018|Angew.Chem.,Int.Ed.|57|7809|doi:10.1002/anie.201803349
CCDC 1577841: Experimental Crystal Structure Determination
2018
Related Article: Yan-Long Ma, Hua Ke, Arto Valkonen, Kari Rissanen, Wei Jiang|2018|Angew.Chem.,Int.Ed.|57|709|doi:10.1002/anie.201711077
CCDC 1577842: Experimental Crystal Structure Determination
2018
Related Article: Yan-Long Ma, Hua Ke, Arto Valkonen, Kari Rissanen, Wei Jiang|2018|Angew.Chem.,Int.Ed.|57|709|doi:10.1002/anie.201711077
CCDC 1828064: Experimental Crystal Structure Determination
2018
Related Article: Jie‐Shun Cui, Qian‐Kai Ba, Hua Ke, Arto Valkonen, Kari Rissanen, Wei Jiang|2018|Angew.Chem.,Int.Ed.|57|7809|doi:10.1002/anie.201803349
CCDC 1821490: Experimental Crystal Structure Determination
2018
Related Article: Paula Sabater, Faviola Zapata, Pedro Molina, Ibon Alkorta, Jose Elguero, Antonio Caballero, Carmen Ramirez de Arellano|2018|Chem. Sel.|3|3855|doi:10.1002/slct.201800809
CCDC 1575263: Experimental Crystal Structure Determination
2018
Related Article: Yan-Long Ma, Hua Ke, Arto Valkonen, Kari Rissanen, Wei Jiang|2018|Angew.Chem.,Int.Ed.|57|709|doi:10.1002/anie.201711077
CCDC 1577819: Experimental Crystal Structure Determination
2018
Related Article: Zoran Džolić, Ngong Kodiah Beyeh, Mario Cetina, Lotta Turunen, Kari Rissanen|2018|Chem.Asian J.|13|164|doi:10.1002/asia.201701426