Search results for "3'"
showing 10 items of 589 documents
CCDC 2177984: Experimental Crystal Structure Determination
2022
Related Article: Elisabet De Bolòs, Marta Martínez-Abadía, Félix Hernández-Culebras, Alison Haymaker, Kyle Swain, Karol Strutyński, Benjamin L. Weare, Javier Castells-Gil□, Natalia M. Padial□, Carlos Martí-Gastaldo□, Andrei N. Khlobystov, Akinori Saeki, Manuel Melle-Franco, Brent L. Nannenga, Aurelio Mateo-Alonso△|2022|J.Am.Chem.Soc.|144|15443|doi:10.1021/jacs.2c06446
CCDC 1997473: Experimental Crystal Structure Determination
2020
Related Article: Christian Mevissen, Carel Kwamen, Leonard Himmel, Xiaofei Chen, Matthias Brückner, Saskia Huda, Christian Göb, Judith Jenniches, Iris Oppel, James Ward, Kari Rissanen, Markus Albrecht|2020|Eur.J.Org.Chem.|2020|5161|doi:10.1002/ejoc.202000843
CCDC 1427937: Experimental Crystal Structure Determination
2017
Related Article: Luca Leoni, Rakesh Puttreddy, Ondřej Jurček, Andrea Mele, Ilaria Giannicchi, Francesco Yafteh Mihan, Kari Rissanen, Antonella Dalla Cort|2016|Chem.-Eur.J.|22|18714|doi:10.1002/chem.201604313
CCDC 1551855: Experimental Crystal Structure Determination
2017
Related Article: Isabella Pyka, Joachim Nikl, Dieter Schollmeyer and Siegfried R. Waldvogel|2017|Eur.J.Org.Chem.|2017|3501|doi:10.1002/ejoc.201700758
CCDC 1518365: Experimental Crystal Structure Determination
2017
Related Article: Soumen Manna, Apurba Bhunia, Soumen Mistri, Julia Vallejo, Ennio Zangrando, Horst Puschmann, Joan Cano, Subal Chandra Manna|2017|Eur.J.Inorg.Chem.||2585|doi:10.1002/ejic.201700046
CCDC 612660: Experimental Crystal Structure Determination
2009
Related Article: E.W.Reinheimer, J.R.Galan-Mascaros, K.R.Dunbar|2009|Synth.Met.|159|45|doi:10.1016/j.synthmet.2008.07.017
CCDC 644919: Experimental Crystal Structure Determination
2008
Related Article: F.Durola, L.Russo, J.-P.Sauvage, K.Rissanen, O.S.Wenger|2007|Chem.-Eur.J.|13|8749|doi:10.1002/chem.200700684
Protective effect of paraoxonase-2 against endoplasmic reticulum stress-induced apoptosis is lost upon disturbance of calcium homoeostasis
2008
PON2 (paraoxonase-2) is a ubiquitously expressed antioxidative protein which is largely found in the ER (endoplasmic reticulum). Addressing the cytoprotective functions of PON2, we observed that PON2 overexpression provided significant resistance to ER-stress-induced caspase 3 activation when the ER stress was induced by interference with protein modification (by tunicamycin or dithiothreitol), but not when ER stress was induced by disturbance of Ca2+ homoeostasis (by thapsigargin or A23187). When analysing the underlying molecular events, we found an activation of the PON2 promoter in response to all tested ER-stress-inducing stimuli. However, only tunicamycin and dithiothreitol resulted i…
TREND-DB—a transcriptome-wide atlas of the dynamic landscape of alternative polyadenylation
2020
AbstractAlternative polyadenylation (APA) profoundly expands the transcriptome complexity. Perturbations of APA can disrupt biological processes, ultimately resulting in devastating disorders. A major challenge in identifying mechanisms and consequences of APA (and its perturbations) lies in the complexity of RNA 3’end processing, involving poorly conserved RNA motifs and multi-component complexes consisting of far more than 50 proteins. This is further complicated in that RNA 3’end maturation is closely linked to transcription, RNA processing, and even epigenetic (histone/DNA/RNA) modifications. Here we present TREND-DB (http://shiny.imbei.uni-mainz.de:3838/trend-db), a resource cataloging…
Detection, validation, and downstream analysis of allelic variation in gene expression.
2009
AbstractCommon sequence variants within a gene often generate important differences in expression of corresponding mRNAs. This high level of local (allelic) control—or cis modulation—rivals that produced by gene targeting, but expression is titrated finely over a range of levels. We are interested in exploiting this allelic variation to study gene function and downstream consequences of differences in expression dosage. We have used several bioinformatics and molecular approaches to estimate error rates in the discovery of cis modulation and to analyze some of the biological and technical confounds that contribute to the variation in gene expression profiling. Our analysis of SNPs and alter…