Search results for "3-d"

showing 10 items of 1132 documents

CCDC 1456785: Experimental Crystal Structure Determination

2016

Related Article: Beáta Fekete, Márta Palkó, István Mándity, Matti Haukka, Ferenc Fülöp|2016|Eur.J.Org.Chem.|2016|3519|doi:10.1002/ejoc.201600434

12-hydroxy-312-diazapentacyclo[13.2.1.0214.0311.0510]octadeca-57916-tetraene-413-dione monohydrateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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1,3-Dipolar Cycloaddition Reactions of Indan-1-one Enamines across Arylnitrile Oxides Leading to Novel Cyclic Isoxazoline Derivatives

2013

Synthesis of a series of cyclic fused-isoxazolines has been accomplished by regioselective and diastereoselective 1,3-dipolar cycloaddition of 3-methylindan-1-one enamines (1a, 1b, 1c) and 3-phenylindan-1-one enamines (2a, 2b, 2c) to arylnitrile oxides (3d, 3e, 3f, 3g, 3h). The structure of the cycloadducts was elucidated by 1H and 13C NMR spectroscopy. The proposed regio- and stereochemistry of fused-compounds (4) and (5) has also been corroborated by two single-crystal X-ray diffraction studies carried out on 4-methyl-8b-morpholinyl-3-(p-tolyl)-4H-3a,8b-dihydroindeno[2,3-d]isoxazoline (4be) and 3-(p-anisyl)-4-phenyl-8b-pyrrolidinyl-4H-3a,8b-dihydroindeno[2,3-d]isoxazoline (5af) and by mea…

13c nmr spectroscopy010405 organic chemistryStereochemistryChemistryOrganic Chemistry13-Dipolar cycloadditionRegioselectivityDensity functional theory010402 general chemistry01 natural sciencesMedicinal chemistryCycloaddition0104 chemical sciencesJournal of Heterocyclic Chemistry
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CCDC 1431346: Experimental Crystal Structure Determination

2015

Related Article: Alexander Ganß, Raquel Belda, Javier Pitarch, Richard Goddard, Enrique García-España, and Stefan Kubik|2015|Org.Lett.|17|5850|doi:10.1021/acs.orglett.5b03027

14174043-Tetraoxa-14112027303746-octaazaheptacyclo[28.22.2.2427.269.22225.23235.24851]tetrahexaconta-6822243234485055576163-dodecaeneSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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Paternal uniparental disomy chromosome 14-like syndrome due a maternal de novo 160 kb deletion at the 14q32.2 region not encompassing the IG- and the…

2015

The human chromosome 14q32 carries a cluster of imprinted genes which include the paternally expressed genes (PEGs) DLK1 and RTL1, as well as the maternally expressed genes (MEGs) MEG3, RTL1as, and MEG8. PEGs and MEGs expression at the 14q32.2-imprinted region are regulated by two differentially methylated regions (DMRs): the IG-DMR and the MEG3-DMR, which are respectively methylated on the paternal and unmethylated on the maternal chromosome 14 in most cells. Genetic and epigenetic abnormalities affecting these imprinted gene clusters result in two different phenotypes currently known as maternal upd(14) syndrome and paternal upd(14) syndrome. However, only few patients carrying a maternal…

14q32.2 imprinted regionGenotypeBiologyPregnancy ProteinsMEG3-DMRGenomic ImprintingPaternal uniparental disomy chromosome 14 [upd(14)pat]GeneticsmedicineHumans14q32.2 maternal deletionEpigenetics"coat-hanger" rib signGeneGenetics (clinical)Sequence DeletionGeneticsMEG3Chromosomes Human Pair 14Comparative Genomic HybridizationIG-DMRMEG3 geneCalcium-Binding ProteinsInfant NewbornChromosomeMembrane ProteinsSyndromeDNA MethylationUniparental Disomymedicine.diseasePrognosisPhenotypeMolecular biologyUniparental disomyDifferentially methylated regionsPhenotypeSkeletal dysplasiaIntercellular Signaling Peptides and ProteinsFemaleRNA Long NoncodingRTL1as geneGenomic imprintingAmerican journal of medical genetics. Part A
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CCDC 1008816: Experimental Crystal Structure Determination

2015

Related Article: Bernd Elsler, Anton Wiebe, Dieter Schollmeyer, Katrin M. Dyballa, Robert Franke, Siegfried R. Waldvogel|2015|Chem.-Eur.J.|21|12321|doi:10.1002/chem.201501604

2'3-Dimethoxy-2-hydroxy-4'55'-trimethylbiphenylSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1479850: Experimental Crystal Structure Determination

2016

Related Article: Shuai Liu, Haofu Dai, Gamall Makhloufi, Christian Heering, Christoph Janiak, Rudolf Hartmann, Attila Mándi, Tibor Kurtán, Werner E. G. Müller, Matthias U. Kassack, Wenhan Lin, Zhen Liu, Peter Proksch|2016|J.Nat.Prod.|79|2332|doi:10.1021/acs.jnatprod.6b00473

213-dihydroxy-7-methyl-615-dioxabicyclo[12.1.0]pentadeca-311-dien-5-one monohydrateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1421617: Experimental Crystal Structure Determination

2016

Related Article: Jakob Wudarczyk, George Papamokos, Vasilis Margaritis, Dieter Schollmeyer, Felix Hinkel, Martin Baumgarten, George Floudas, Klaus Müllen|2016|Angew.Chem.,Int.Ed.|55|3220|doi:10.1002/anie.201508249

22-Dimethyl-23-dihydro-1H-benzimidazole-4567-tetracarbonitrile tetrahydrofuran solvateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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Synthesis and anti-HIV activity of 2,3-diaryl-1,3-thiazolidin-4-(thi)one derivatives.

2002

Several 2,3-diaryl-1,3-thiazolidine-4-thione derivatives and 2,3-diaryl-1,3-thiazolidin-4-ones bearing a methyl group at C-5 position have been synthesized and tested as anti-HIV agents. The results of the in vitro tests showed that some of them proved to be effective inhibitors of HIV-1 replication.

23-Diaryl-13-thiazolidine-4-thioneAnti-HIV activity23-Diaryl-13-thiazolidin-4-oneStereochemistryAnti-HIV AgentsCell SurvivalPharmaceutical ScienceVirus ReplicationChemical synthesischemistry.chemical_compoundInhibitory Concentration 50Structure-Activity RelationshipThiadiazolesDrug DiscoveryThiadiazolesmedicineTumor Cells CulturedStructure–activity relationshipHumansAnti hiv activityReverse-transcriptase inhibitorGeneral MedicineSettore CHIM/08 - Chimica FarmaceuticaIn vitrochemistryNNRTIsLactamHIV-1EpimerMethyl groupmedicine.drugFarmaco (Societa chimica italiana : 1989)
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CCDC 1035162: Experimental Crystal Structure Determination

2014

Related Article: Felicitas Lips, Akseli Mansikkamäki, James C. Fettinger, Heikki M. Tuononen, Philip P. Power|2014|Organometallics|33|6253|doi:10.1021/om500947x

23-Diphenyl-11-bis((22''66''-tetraisopropyl-11':3'1''-terphenyl-2'-yl)sulfanyl)-1H-silireneSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 285998: Experimental Crystal Structure Determination

2006

Related Article: S.Amriou, Changsheng Wang, A.S.Batsanov, M.R.Bryce, D.F.Perepichka, E.Orti, R.Viruela, J.Vidal-Gancedo, C.Rovira|2006|Chem.-Eur.J.|12|3389|doi:10.1002/chem.200501326

27-di-iodo-9-(45-dimethyl-13-dithiol-2-ylidene)fluoreneSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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