Search results for "35"
showing 10 items of 2413 documents
Manufacturing Risk Identification in the Steel Industry
2020
The steel manufacturing industry is an inseparable part of the nuclear power plant construction project. This industry is a business full of dynamics, risks, and challenges. The implementation of risk management becomes an obligation that must be executed in managing this very complex project. In general, risk management in manufacturing includes steps to understand and identify potential problems that may occur, evaluate, monitor, and handle risks. The main risk management objectives are to prevent or minimize adverse effects due to unforeseen events through risk aversion or preparation of contingency plans related to those risks. This paper describes the identification of risk factors and…
Los primeros grados de la Universidad de Orihuela (1610-1643)
2017
El ?Alivio de las Indias?. la Real Hacienda Filipina, 1565-1800
2019
Previo al estudio de la Real Hacienda filipina, el trabajo se centrará en la definición del marco territorial, la función del archipiélago en la estrategia imperial y la gran transformación de finales del siglo xVIII que afectó a su situación en el conjunto colonial. En segundo lugar, se expondrá el estado de la cuestión y las principales hipótesis sobre la evolución del Tesoro filipino y los problemas que planteaba su viabilidad, así como las fuentes y la metodología empleadas. A continuación se examinarán las grandes tendencias de la Hacienda en el largo plazo y los componentes del ingreso y el gasto, para finalizar con algunas conclusiones, en especial la respuesta a la siguiente pregunt…
Ferrer del Río: Rodrigo de Mendoza, noble y coleccionista del Renacimiento
2020
La construcción del Colegio de la Compañía de Jesús de Alicante y sus artífices
2014
Cuando el trazo velado delata al maestro. Dibujos subyacentes en la obra pictórica de Joan de Joanes: de la creación a las prácticas de taller
2018
How selection of collaborating partners impact on the green performance of global businesses? An empirical study of green sustainability
2020
In recent days, both collaboration and sustainability have become an integral part of many global supply chains to achieve business excellence. Although previous literature and actual practices confirmed the successful implementation of sustainability practices through supply chain collaborations, it is not clear how collaborating partners can support financial and environmental performance, and hence strengthen the partnership performance in the global supply chains. To address this practice-based research question, we test the theoretical underpinning of suppliers and logistics partners in relation to required skills selection. We capture the depth of interdependencies in collaborations f…
Diversity, evolution, and function of myriapod hemocyanins.
2018
Background Hemocyanin transports O2 in the hemolymph of many arthropod species. Such respiratory proteins have long been considered unnecessary in Myriapoda. As a result, the presence of hemocyanin in Myriapoda has long been overlooked. We analyzed transcriptome and genome sequences from all major myriapod taxa – Chilopoda, Diplopoda, Symphyla, and Pauropoda – with the aim of identifying hemocyanin-like proteins. Results We investigated the genomes and transcriptomes of 56 myriapod species and identified 46 novel full-length hemocyanin subunit sequences in 20 species of Chilopoda, Diplopoda, and Symphyla, but not Pauropoda. We found in Cleidogona sp. (Diplopoda, Chordeumatida) a hemocyanin-…
EvalMSA: A Program to Evaluate Multiple Sequence Alignments and Detect Outliers
2016
8 páginas, 3 figuras, 2 tablas.
Targeting Voltage-Dependent Calcium Channels with Pregabalin Exerts a Direct Neuroprotective Effect in an Animal Model of Multiple Sclerosis
2018
Background/aims Multiple sclerosis (MS) is a prototypical autoimmune central nervous system (CNS) disease. Particularly progressive forms of MS (PMS) show significant neuroaxonal damage as consequence of demyelination and neuronal hyperexcitation. Immuno-modulatory treatment strategies are beneficial in relapsing MS (RMS), but mostly fail in PMS. Pregabalin (Lyrica®) is prescribed to MS patients to treat neuropathic pain. Mechanistically, it targets voltage-dependent Ca2+ channels and reduces harmful neuronal hyperexcitation in mouse epilepsy models. Studies suggest that GABA analogues like pregabalin exert neuroprotective effects in animal models of ischemia and trauma. Methods We tested t…