Search results for "35"
showing 10 items of 2413 documents
Artificial cartilage bio-matrix formed of hyaluronic acid and Mg2+-polyphosphate.
2016
Here we show that inorganic polyphosphate (polyP), a polyanionic metabolic regulator consisting of multiple phosphate residues linked by energy-rich phosphoanhydride bonds, is present in the synovial fluid. In a biomimetic approach, to enhance cartilage synthesis and regeneration, we prepared amorphous polyP microparticles with Mg2+ as counterions. The particles were characterised by X-ray diffraction (XRD), energy-dispersive X-ray (EDX) and Fourier transformed infrared spectroscopic (FTIR) analyses. Similar particles were obtained after addition of Mg2+ ions to a solution containing hyaluronic acid, as a major component of the synovial fluid, and soluble Na-polyP. The viscous paste-like ma…
Solvability of a first order system in three-dimensional non-smooth domains
1985
summary:A system of first order partial differential equations is studied which is defined by the divergence and rotation operators in a bounded nonsmooth domain $\Omega\subset \bold R^3$. On the boundary $\delta\Omega$, the vanishing normal component is prescribed. A variational formulation is given and its solvability is investigated.
Networking strategies as enabler for competitive advantage creation: a market-based and a resource-based perspectives
2010
The purpose of this work is to explore the potential of networking strategy as a source of competitive advantage by integrating market-based and resource-based logics. According to the former logic a firm identifies operations performance objectives as drivers for achieving its wished competitive position and advantage. According to the latter logic the firm achieves a competitive advantage through the obtainment and/or the creation of valuable, rare, imperfectly imitable, and not substitutable resources. Both operations performance objectives and strategic resource needs should, thus, directly affect networking strategy decisions. The question is whether they effectively do and how. In thi…
Achieving operations performance objectives through networking strategy
2010
The main objective of this paper is to investigate how firms make strategic networking decisions in order to pursue competitive advantage. Literature analysis with theory building purposes and two case studies to support our theoretical findings and to explore the linkages between networking strategy and operations performance objectives constitute our research methods. Our analysis led to the definition of networking strategy in terms of decisional dimensions, and found effective linkages between networking decisions made by managers and wished operations performance objectives.
La gonorrea oggi
2013
Review of Abnormal Self-Knowledge in Major Depressive Disorder
2019
Background: Major depressive disorder (MDD) is an affective disorder that is harmful to both physical and mental health. Abnormal self-knowledge, which refers to abnormal judgments about oneself, is a core symptom of depression. However, little research has summarized how and why patients with MDD differ from healthy individuals in terms of self-knowledge. Objective: To gain a better understanding of MDD, we reviewed previous studies that focused on the behavioral and neurological changes of self-knowledge in this illness. Main Findings: On the behavioral level, depressed individuals exhibited negative self-knowledge in an explicit way, while more heterogeneous patterns were reported in imp…
On Limits at Infinity of Weighted Sobolev Functions
2022
We study necessary and sufficient conditions for a Muckenhoupt weight $w \in L^1_{\mathrm{loc}}(\mathbb R^d)$ that yield almost sure existence of radial, and vertical, limits at infinity for Sobolev functions $u \in W^{1,p}_{\mathrm{loc}}(\mathbb R^d,w)$ with a $p$-integrable gradient $|\nabla u|\in L^p(\mathbb R^d,w)$. The question is shown to subtly depend on the sense in which the limit is taken. First, we fully characterize the existence of radial limits. Second, we give essentially sharp sufficient conditions for the existence of vertical limits. In the specific setting of product and radial weights, we give if and only if statements. These generalize and give new proofs for results of…
SETAC GLB and SETAC Europe SAC: a liaison promoting the next generation of ecotoxicologists and environmental chemists
2018
Environmental sciences Europe 30(1), 41s12302-018-0171-z (2018). doi:10.1186/s12302-018-0171-z
Understanding the price drivers of successful apps in the mobile app market
2016
In this paper, we take the perspective of app developers. Specifically, based on a sample of top paid apps from three major app stores, i.e., App Store, Google Play, and Blackberry World, we construct a hedonic price model to examine the role of relevant factors in price formation in the app market. Our results suggest a strong evidence of two-sided market effects. In fact, the lower price charged for apps operating as two-sided markets reflect the strategy of subsidising users, due to the positive cross-side externalities they exert on valuable third parties. Surprisingly, the effects of trialability, in-app purchase and mechanisms to build reputation are not significant in the context of …
The Role of e-Tutor Competencies in Postgraduate e-Learning Courses: Spotlight on Emotion Management
2021
The role of e-learning in the existing and challenging educational era is crucial. However, it is necessary to overcome some drawbacks such as feelings of isolation and a lack of emotional contact. In this sense, emotion management is a key driver of student satisfaction in e-learning, which is significantly related to students’ motivation, learning, cognitive strategies, self-regulation, and personality antecedents in the classroom. This article examines an online postgraduate course in financial statements auditing, describing the resources used by the e-tutor to conduct affective tutorials, reduce students’ feelings of isolation, increase student involvement, and achieve success in e-lea…