Search results for "36"

Regulation of calcium signalling by docosahexaenoic acid in human T-cells: implication of CRAC channels

2000

Abstract We elucidated the role of docosahexaenoic acid (DHA) on the increases in free intracellular calcium concentrations, [Ca2+]i, in human (Jurkat) T-cell lines. DHA evoked an increase in [Ca2+]i in a dose-dependent manner in these cells. Anti-CD3 antibody, known to stimulate increases in Ca2+ from endoplasmic reticulum (ER) via the production of inositol trisphosphate, also evoked increases in [Ca2+]i in Jurkat T-cells. We also used thapsigargin which inhibits Ca2+-ATPase of the ER and, therefore, increases Ca2+ in the cytosol. Interestingly, addition of DHA during the thapsigargin-induced peak response exerted an additive effect on the increases in [Ca2+]i in human T-cells, indicating…

Non solo Platone. Il primato dell'oralità nel retore Alcidamante

2020

Il saggio è dedicato all’orazione Sugli autori dei discorsi scritti o sui sofisti, attribuita al retore Alcidamante, discepolo di Gorgia e attivo in Atene tra il 410 e il 365 a.C. Argomento dell’orazione è il serrato confronto tra due differenti modalità oratorie, l’autoschediazein (“parlare a braccio”) — cui Alcidamente accorda una netta superiorità — e il "gegrammena legein (“pronunciare discorsi scritti”). L’interesse di questo testo (databile con buona approssimazione intorno al 390 a. C) consiste essenzialmente nel rappresentare un punto di vista specificamente retorico sulla questione delle differenze tra scritto e parlato. Nonostante alcune significative convergenze con il ben più ce…

La formación docente y los sueños sobre el aula 3.0

2017

En el presente trabajo abordamos, desde la perspectiva cultural y educativa, la relación de la institución escolar con su entorno tecnológico. El objetivo es analizar el empoderamiento de los distintos agentes escolares mediante la experiencia reflexiva, especialmente en el caso del profesorado. La metodología adoptada en este texto, se basa en estrategias de metaevaluación de nuestros propios trabajos de campo; en particular, los estudios centrados sobre los programas institucionales Escuela 2.0 y en el de la digitalización de los contenidos curriculares. Una de las conclusiones es que la mayor presencia de las tecnologías en los centros escolares no se corresponde con la renovación de las…

An experimental investigation on the long-term compatibility of preheated crude palm oil in a large compression ignition diesel engine

2018

An experimental study was carried out on a large stationary compression ignition engine to evaluate the long-term compatibility and durability issues associated with the use of crude palm oil as fuel. Two different preheating temperatures (60 and 80 °C) were adopted to assess the potential improvements related to lower fuel viscosity. The results obtained, in terms of in-cylinder carbon deposits and engine wear, were compared with the results obtained using ordinary diesel fuel. For each fuel and preheating temperature, the engine was operated for 300 consecutive h, during which several engine lubricant samples were collected and analysed to determine soot and fuel contaminations, viscosity…

Abdominal splenosis and its differential diagnoses: What the radiologist needs to know

2021

Abstract Splenosis is a benign acquired condition characterized by the presence of heterotopic viable splenic tissue in other organs or within cavities such as peritoneum, retroperitoneum, or thorax after splenic trauma or surgery. Abdominal splenosis is often an incidental finding and computed tomography and magnetic resonance usually allow a confident diagnosis. The typical enhancement that parallels the spleen is a useful hallmark of splenosis. Splenic implants lack contrast uptake in the hepatobiliary phase and show high signal at high b-values on diffusion-weighted images. In some cases splenosis may mimic malignant and benign conditions in the peritoneum as well as in hollow and paren…

Radiofrequency ablation for thyroid nodules: which indications? The first Italian opinion statement

2015

Nodular thyroid disease is a very common finding in clinical practice, discovered by ultrasound (US) in about 50 % of the general population, with higher prevalence in women and in the elderly [1–4]. Whereas therapeutic flowchart is quite established and shared for malignant lesions, multiple options are now available for patients presenting with benign thyroid nodules, ranging from simple clinical and US follow-up to thyroid surgery. The majority of thyroid nodules, benign by fine-needle aspiration, are asymptomatic, stable, or slow-growing over time and require no treatment. Nevertheless, large thyroid nodules may become responsible for pressure symptoms, resulting in neck discomfort, cos…

Anatomia TC del cuore e classificazione in segmenti coronarici

2007

Modulo per l'addestramento alla aspirazione di follicoli ovarici sotto controllo ecografico, comprendente: un simulatore delle pelvi femminile, inclu…

2003

Aortic valve and vascular calcium score in pre-TAVI CT: correlation with early post-procedural complications

2023

Abstract Purpose The aim of our study was to evaluate the prevalence of early complications after Transcatheter Aortic Valve Implantation (TAVI) and their correlation with the Calcium Score (CS) of the aortic valve, aorta and ilio-femoral arteries derived from pre-procedural computed tomography (CT). Materials and methods We retrospectively reviewed 226 patients (100 males, mean age 79.4 ± 6.7 years) undergoing 64-slice CT for pre-TAVI evaluation from January 2018 to April 2021. The population was divided into CS quartiles. Results Overall, 173 patients underwent TAVI procedure, of whom 61% presented paravalvular leak after the procedure, 28% presented bleeding or vascular complications, 25…

Resting state FMRI: A tool to investigate functional connectivity modulation induced by transcranial direct current stimulation of the motor network

2016

Introduction: Resting-state functional connectivity (fcMRI) represents a novel fMRI approach that allows detection of temporal correlations in spontaneous BOLD signal oscillations while subjects rest quietly in the scanner. Under resting conditions the brain is engaged in spontaneous activity that causes a low frequencies (<0.1 Hz) BOLD signal fluctuations. Functional connectivity (FC) can be defined as the synchrony of neural activity among spatially distant regions. Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique that is known to modulate cortical activity and FC among brain regions, as measured by functional magnetic resonance imaging. This st…