Search results for "38"
showing 10 items of 1730 documents
CCDC 1553488: Experimental Crystal Structure Determination
2018
Related Article: Djamille Azazna, Marine Lafosse, Julie Rivollier, Jialan Wang, Imen Ben Cheikh, Michel Meyer, Pierre Thury, Jean-Pierre Dognon, Gaspard Huber, Marie-Pierre Heck|2018|Chem.-Eur.J.|24|10793|doi:10.1002/chem.201801468
p38 MAPK activation is required for Paracentrotus lividus skeletogenesis
2008
We investigated the p38 MAPK role during sea urchin, Paracentrotus lividus, development. We found that at the morula stage, before the onset of skeletogenesis, p38 MAPK shows a peak of activity, and we tested whether p38 MAPK activity has any effect on skeletogenesis. By immunohistochemistry on whole-mount embryos we show the preferential localization of the active p38 form both in the presumptive PMCs and bilateral spiculo- genesis centers in control embryos, and in the radialized supernumerary spiculogenesis centers induced by NiCl2 treatment. By using SB203580, a p38 MAPK specific inhibitor, we show that p38 activity is required both for the initial triradiate spicule rudiments formation…
Imperfect information and consumer inflation expectations:evidence from microdata
2017
This paper explores which factors trigger an adjustment in consumers’ inflation expectations and looks at the implications regarding forecast errors. We find support for imperfect information models, as inflation volatility and news trigger an adjustment in expectations. Furthermore, we document that individual expectations become more accurate if they have been adjusted.
Impact of Distressing Media Imagery on Children
2016
Children are particularly fragile and vulnerable to the impact of traumatic events or their mediated representation because they lack the skills and experience in the management of difficult information. Children have different concepts of health and disaster than adults and institutions, depending mainly on their cognitive, emotional, social, psychological, and physical development. If left alone with threatening messages, children are less able to fully understand the information to which they had been exposed. Therefore, they may fail to integrate the external data into their psychological schema of coping strategies. Children usually count on caregivers to deal with stressors, and they …
The Structure and Behavioural Effects of Revealed Social Identity Preferences
2020
A large body of evidence shows that social identity affects behaviour. However, our understanding of the substantial variation of these behavioural effects is still limited. We use a novel laboratory experiment to measure differences in preferences for social identities as a potential source of behavioural heterogeneity. Facing a trade-off between monetary payments and belonging to different groups, individuals are willing to forego significant earnings to avoid belonging to certain groups. We then show that individual differences in these foregone earnings correspond to the differences in discriminatory behaviour towards these groups. Our results illustrate the importance of considering in…
The financial performance of listed companies in pursuit of the Sustainable Development Goals (SDG)
2021
[EN] Socially responsible companies whose values are aligned with the United Nations Sustainable Development Goals (UN SDGs) contribute to creating wealth and long-term economic and social value. This alignment leads to a competitive advantage based on the triple bottom line that enhances financial performance. In this paper, fuzzy-set qualitative comparative analysis (fsQCA) is used to identify the configurations of conditions that lead to high or low financial performance (return on equity) for a sample of companies in the IBEX 35. Firms should adopt business models that embrace the SDGs because sustainability-based models can ensure not only the present but also the future of generations…
Oleuropein protects against dextran sodium sulfate-induced chronic colitis in mice.
2013
The anti-inflammatory effect of oleuropein (1), the major phenolic secoiridoid in Olea europaea, was evaluated in an experimental model of chronic colitis in mice. Animals were exposed to four repeated cycles of dextran sodium sulfate in drinking water followed by a 7-day rest period. Animals receiving a standard diet supplemented with 0.25% of 1 (equivalent to 500 mg/kg/day) for 56 days exhibited a decrease of inflammatory symptoms, as reflected by improvement of disease activity index and histopathological changes. It was found that 1 decreased inflammatory cell recruitment and the release of inflammatory cytokines interleukin (IL)-1β and IL-6 with increased IL-10 levels in colon tissue. …
SNP variation in the bitter taste TAS2R38 gene evaluated in student populations of several italian universities and isolates
2007
People vary widely in their sensitivities to bitter compounds, but the all intercorrelation of these sensitivities is unknown. The study of genetic influences on bitter taste perception originated from the discovery in the 1930s that some individuals had taste to phenylthiocarbamide(PTC), whereas others found it extremely bitter. Subsequently, many studies were carried out on PTC and the structurally related compound propylthiouracil (PROP) to assess this viability and to determine the root causes. Initial family studies strongly suggested that PTC no tasting was due to a recessive allele in a single gene and heritability was estimated at 0,5. 55-85% of variation in PTC detection. The PTC ge…
Direct assessment of the sensitivity drift of SQM sensors installed outdoors
2021
Long-term monitoring of the evolution of the artificial night sky brightness is a key tool for developing science-informed public policies and assessing the efficacy of light pollution mitigation measures. Detecting the underlying artificial brightness trend is a challenging task, since the typical night sky brightness signal shows a large variability with characteristic time scales ranging from seconds to years. In order to effectively isolate the weak signature of the effect of interest, determining the potential long term drifts of the radiance sensing systems is crucial. If these drifts can be adequately characterized, the raw measurements could be easily corrected for them and transfor…
Optical pulsations from a transitional millisecond pulsar
2017
Weakly magnetic, millisecond spinning neutron stars attain their very fast rotation through a 1E8-1E9 yr long phase during which they undergo disk-accretion of matter from a low mass companion star. They can be detected as accretion-powered millisecond X-ray pulsars if towards the end of this phase their magnetic field is still strong enough to channel the accreting matter towards the magnetic poles. When mass transfer is much reduced or ceases altogether, pulsed emission generated by particle acceleration in the magnetosphere and powered by the rotation of the neutron star is observed, preferentially in the radio and gamma-ray bands. A few transitional millisecond pulsars that swing betwee…