Search results for "4-Benzoxazine"

showing 2 items of 2 documents

Synthesis of the New Ring System 2-Oxo-[1,4]oxazino[3,2-e]indole, Heteroanalogue of Angelicin

2009

A convenient synthesis of the 2-oxo-[1,4]oxazino[3,2-e]indole ring system, an heteroanalogue of Angelicin, is reported. Our synthetic approach consisted of the annelation of the oxazine ring on the indole moiety using 4-amino-5-hydroxy indoles as building blocks. The antiproliferative activity of the new compounds either in the dark or under UVA irradiation was investigated.

Indole testAnnulationStereochemistryOrganic Chemistry1; 4-Oxazinoindoles; 1; 4-Benzoxazines; Angelicin heteroanalogue; 4-Amino-5-hydroxy indoles114-Benzoxazine14-OxazinoindoleRing (chemistry)Biochemistry4-Oxazinoindoles4-Benzoxazineschemistry.chemical_compoundAngelicinchemistryDrug DiscoveryMoiety4-Amino-5-hydroxy indolesUva irradiationAngelicin heteroanalogue
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CCDC 742251: Experimental Crystal Structure Determination

2009

Related Article: K.Ejsmont, J.-P.Joly, E.Wenger, B.Guillot, C.Jelsch|2009|Acta Crystallogr.,Sect.C:Cryst.Struct.Commun.|65|o342|doi:10.1107/S0108270109019544

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters4-Benzoyl-34-dihydro-2H-14-benzoxazine-2-carbonitrileExperimental 3D Coordinates
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