Search results for "4-dihydro-2"

showing 8 items of 28 documents

CCDC 1875758: Experimental Crystal Structure Determination

2018

Related Article: Carlos Vila, Arturo Tortosa, Gonzalo Blay, M. Carmen Muñoz, José R. Pedro|2019|New J.Chem.|43|130|doi:10.1039/C8NJ05577G

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters68-dichloro-4-(4-hydroxy-1H-indol-5-yl)-34-dihydro-2lambda613-benzothiadiazine-22(1H)-dione monohydrateExperimental 3D Coordinates
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CCDC 781064: Experimental Crystal Structure Determination

2010

Related Article: I.Bergner, C.Wiebe, N.Meyer, T.Opatz|2009|J.Org.Chem.|74|8243|doi:10.1021/jo901759u

Space GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates3-(2-Bromophenyl)-5-(2-naphthyl)-34-dihydro-2H-pyrrole-2-carbonitrile
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CCDC 117866: Experimental Crystal Structure Determination

1999

Related Article: S.Perrin, K.Monnier, B.Laude, M.Kubicki, O.Blacque|1999|Eur.J.Org.Chem.|1999|297|doi:10.1002/(SICI)1099-0690(199901)1999:13.0.CO;2-J

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameterstrans-(Ethyl 36-diphenyl-3-p-tolylamino-34-dihydro-2-pyridone-4-carboxylate)Experimental 3D Coordinates
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CCDC 970428: Experimental Crystal Structure Determination

2013

Related Article: Y. Rousselin, H. Laureano, A. Clavel|2013|Acta Crystallogr.,Sect.E:Struct.Rep.Online|69|o1794|doi:10.1107/S1600536813030377

Space GroupCrystallographyCrystal SystemN-Benzyl-2-(6-fluoro-34-dihydro-2H-chromen-2-yl)-2-hydroxyethanaminium bromideCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1537327: Experimental Crystal Structure Determination

2017

Related Article: J. Lasri, N.E. Eltayeb, M. Haukka, B.A. Babgi|2017|Acta Crystallogr.,Sect.E:Cryst.Commun.|73|528|doi:10.1107/S2056989017003929

Space GroupCrystallographydichloro-bis(N-(22-dimethyl-34-dihydro-2H-pyrrol-5-yl)acetamide)-palladium(ii) dihydrateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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Comparison of the contractile effects of endothelin-1 and sarafotoxin S6b in goat isolated cerebral arteries

1992

1. The effects of endothelium-derived endothelin-1 and snake venom-derived sarafotoxin S6b, peptides with striking structural and functional similarities, were examined and compared in isolated middle cerebral arteries of goats. 2. Endothelin-1 and sarafotoxin S6b contracted cerebral arteries in a concentration-dependent manner. The potency of endothelin-1 (EC50 = 4.9 (3.9-6.2) x 10(-10) M) was about ten times higher than that of sarafotoxin S6b (EC50 = 5.5 (4.4-6.9) x 10(-9) M). The tension returned to basal values after repeated washings and contraction with endothelin-1 could be reproduced. Endothelin-1 and sarafotoxin S6b induced further contraction in arteries precontracted with prosta…

medicine.hormonemedicine.medical_specialtyContraction (grammar)IndomethacinCerebral arteriesProstacyclinViper Venomscomplex mixturesEndothelinsNicardipinechemistry.chemical_compoundInternal medicinemedicineAnimalsVasoconstrictor AgentsPharmacologyDose-Response Relationship DrugEndothelinsGoats3-Pyridinecarboxylic acid 14-dihydro-26-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)- Methyl esterCerebral ArteriesEndothelin 1EGTAEndocrinologychemistryVasoconstrictioncardiovascular systemFemaleEndothelium Vascularmedicine.symptomVasoconstrictionResearch Articlecirculatory and respiratory physiologymedicine.drugMuscle contractionBritish Journal of Pharmacology
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Effects of endothelin-1 on the cerebrovascular bed of the goat.

1991

Abstract The aim of the present study was to analyze the effects of endothelin-1 (ET-1) in the cerebrovascular bed of the goat, the importance of endothelial integrity and the contribution of extracellular Ca2+ to these responses. We measured isometric tension and 45Ca2+ uptake in isolated middle cerebral arteries, and cerebral blood flow (CBF) in unanesthetized animals. ET-1 elicited concentration-dependent contractions which were potentiated in arteries without endothelium. Ca2+-free medium and nicardipine inhibited, and Bay K 8644 potentiated the ET-1-induced contractions. ET-1 enhanced 45Ca2+ uptake in isolated arteries. Injections of ET-1 directly into the cerebral circulation decrease…

medicine.medical_specialtyEndotheliumCerebral arteriesNicardipineIn Vitro TechniquesMuscle Smooth VascularCerebral circulationNicardipineInternal medicinemedicine.arteryIsometric ContractionmedicineAnimalsPharmacologyChemistryCalcium RadioisotopesEndothelinsGoatsAnatomy3-Pyridinecarboxylic acid 14-dihydro-26-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)- Methyl esterEndothelin 1Acetylcholinemedicine.anatomical_structureEndocrinologyCerebral blood flowCerebrovascular CirculationMiddle cerebral arteryPotassiumCalciumFemaleBlood vesselmedicine.drugEuropean journal of pharmacology
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CCDC 781063: Experimental Crystal Structure Determination

2010

Related Article: I.Bergner, C.Wiebe, N.Meyer, T.Opatz|2009|J.Org.Chem.|74|8243|doi:10.1021/jo901759u

trans-5-(1-Benzofuran-2-yl)-3-phenyl-34-dihydro-2H-pyrrole-2-carbonitrileSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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