Search results for "41"

showing 10 items of 3365 documents

Assessing the profitability of investment projects using ordered fuzzy numbers

2019

Background: This article is motivated by the fact that most approaches to capital budgeting are deterministic. In reality, the capital budgeting problem is accompanied by the uncertainty and risk associated with dealing with imprecise data. Taking this uncertainty into account when performing analyses and calculations not only helps to better measure the profitability of investment projects, but also to expand the applicability of capital budgeting methods under real-life or uncertain conditions. The major contribution of this paper is the development of a novel approach to assessing the profitability of an investment project in the presence of uncertainty. Methods: We present a novel appro…

ordered fuzzy numberprojectfuzzy numberlcsh:Marketing. Distribution of productsinvestment projectlcsh:HF5410-5417.5capital budgetingNPVLogForum
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Proton Exchange Membrane Fuel Cells (PEMFCs): Advances and Challenges

2021

The study of the electrochemical catalyst conversion of renewable electricity and carbon oxides into chemical fuels attracts a great deal of attention by different researchers. The main role of this process is in mitigating the worldwide energy crisis through a closed technological carbon cycle, where chemical fuels, such as hydrogen, are stored and reconverted to electricity via electrochemical reaction processes in fuel cells. The scientific community focuses its efforts on the development of high-performance polymeric membranes together with nanomaterials with high catalytic activity and stability in order to reduce the platinum group metal applied as a cathode to build stacks of proton …

organic polymersMaterials sciencePolymers and PlasticsHydrogenMembrane electrode assemblymembrane–electrode assemblyNanoparticleProton exchange membrane fuel cellchemistry.chemical_elementOrganic chemistryNanotechnologyGeneral ChemistryReviewElectrochemistryNanomaterialsCatalysisElectroquímicafuel cellMembraneQD241-441chemistryproton conductivityMaterialsproton exchange membranePolymers
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One-pot cross-enyne metathesis (CEYM)-Diels-Alder reaction of gem-difluoropropargylic alkynes.

2013

Propargylic difluorides 1 were used as starting substrates in a combination of cross-enyne metathesis and Diels–Alder reactions. Thus, the reaction of 1 with ethylene in the presence of 2nd generation Hoveyda–Grubbs catalyst generates a diene moiety which in situ reacts with a wide variety of dienophiles giving rise to a small family of new fluorinated carbo- and heterocyclic derivatives in moderate to good yields. This is a complementary protocol to the one previously described by our research group, which involved the use of 1,7-octadiene as an internal source of ethylene.

organo-fluorineEthyleneDieneone-pot reactionDifluorideOrganic ChemistryMetathesisEnyne metathesisFull Research PaperCatalysislcsh:QD241-441chemistry.chemical_compoundChemistrychemistrylcsh:Organic chemistryDiels–AlderMoietyOrganic chemistrylcsh:Qcross metathesislcsh:Sciencepropargylic difluoridesDiels–Alder reactionBeilstein journal of organic chemistry
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Negotiating parenting practices: the arguments and justifications of Finnish couples

2021

This article explores Finnish different-sex couples’ (n = 12) negotiations on their parental division of labour. Theoretically, the article is based on the literature on gendered parenting practices and relational negotiations. Our discourse analysis reveals how the couples produced ‘togetherness’ and ‘our family’ by representing their care practices as agreements, irrespective of whether the care was described as equally shared or distinctly gendered. Disagreements reflecting more individualistic tones, and mainly resulting from the mothers’ sense of unfairness, were especially foregrounded when the distribution of household duties was discussed. The analysis also revealed how men cited in…

parenting practicesparisuhdekotityövanhemmuustasa-arvotyönjako5142 Social policynegotiationcouple interviewslastenhoito5141 SociologyryhmähaastattelutFinlandgender equality
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Hormesis: Decoding Two Sides of the Same Coin

2015

In the paradigm of drug administration, determining the correct dosage of a therapeutic is often a challenge. Several drugs have been noted to demonstrate contradictory effects per se at high and low doses. This duality in function of a drug at different concentrations is known as hormesis. Therefore, it becomes necessary to study these biphasic functions in order to understand the mechanistic basis of their effects. In this article, we focus on different molecules and pathways associated with diseases that possess a duality in their function and thus prove to be the seat of hormesis. In particular, we have highlighted the pathways and factors involved in the progression of cancer and how t…

pathwayslcsh:RLow dosemimeticsHormesislcsh:Medicinelcsh:RS1-441Pharmaceutical ScienceDrug administrationReviewAdaptive responseStimulus (physiology)BiologybiphasicBioinformaticslcsh:Pharmacy and materia medicahormesisDrug DiscoverycancerstressorMolecular MedicinePharmaceuticals
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Impact of Ageing on Pea Protein Volatile Compounds and Correlation with Odor

2022

Vegetal proteins are of high interest for their many positive aspects, but their ‘beany’ off-flavor is still limiting the consumer’s acceptance. The aim of this work was to investigate the conservation of pea protein isolate (PPI) during time and especially the evolution of their organoleptic quality under two storage conditions. The evolution of the volatile compounds, the odor and the color of a PPI has been investigated during one year of storage. PPI was exposed to two treatments mimicking a lack of control of storage conditions: treatment A with light exposition at ambient temperature (A—Light 20 °C) and treatment B in the dark but with a higher temperature …

pea proteinVolatile Organic CompoundsHot Temperaturestorage conditionsPharmaceutical ScienceHS-SPME-GC-MSOrganic chemistry‘beany’ off-flavorAnalytical Chemistrypea protein; storage conditions; aroma; HS-SPME-GC-MS; ‘beany’ off-flavorQD241-441aromaChemistry (miscellaneous)OdorantsDrug DiscoveryMolecular Medicine[SDV.BV] Life Sciences [q-bio]/Vegetal BiologyPhysical and Theoretical Chemistry[SDV.MP] Life Sciences [q-bio]/Microbiology and ParasitologyPea ProteinsMolecules
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The importance of psychological variables in the perceived exertion of young football players

2017

Las escalas para medir la percepción del esfuerzo están entre los métodos que han sido utilizados para el control y la evaluación de la carga interna del entrenamiento en deportes de equipo como el fútbol. Debido a su naturaleza psicofisiológica, su registro proporciona información proveniente tanto de indicadores fisiológicos como psicológicos del deportista. Dentro del marco de la Teoría de la Autodeterminación (SDT, Self Determination Theory; Deci & Ryan, 1985; Ryan & Deci, 2017) y de la Teoría de las Metas de Logro (AGT, Achievement Goal Theory; Ames, 1992; Nicholls, 1989), en esta tesis doctoral se estudian tanto las variables contextuales desadaptativas (dimensiones del clima motivaci…

perceived exertionyoung football players611400610608self-determination theorymotivational climate610609exhaustionachievement goal theoryaerobic trainingmotivational psychological variables241106
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Unpacking the link between family socioeconomic status and civic engagement during the transition to adulthood: Do work values play a role?

2017

We investigated whether the link between family-of-origin socioeconomic status (SES) and civic engagement in young adulthood is mediated by youth’s work values, i.e., the desired characteristics of their current or future jobs. We used data from a Finnish study: 2004 (age 16–18, NT1 = 1,301); 2011 (age 23–25, N T2 = 1,096); and 2014 (age 25–27, NT3 = 1,138). A lower family SES in 2004 was negatively related to youth’s civic engagement in 2014. Lower family SES predicted the importance that youth attached to extrinsic job rewards (e.g., good pay) in 2011, but not the importance of intrinsic job rewards (e.g., learning opportunities). Extrinsic work values, in turn, predicted lower civic enga…

perhe (ilmiöt)civic engagementmedia_common.quotation_subjectwork values050109 social psychologyWork valuesfamily socioeconomic statustyösosioekonominen asemayoung adulthoodarvot (käsitykset)0502 economics and businessDevelopmental and Educational PsychologyCivic engagementPersonality0501 psychology and cognitive sciencesarvotYoung adultLife-span and Life-course StudiesSocioeconomic statusta515Applied Psychologymedia_commonnuoret aikuisetTransition (fiction)05 social sciencesSocializationhumanitiesta5141Life course approachPsychologySocial psychology050203 business & managementApplied Developmental Science
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Inulin-Based Polymeric Micelles Functionalized with Ocular Permeation Enhancers: Improvement of Dexamethasone Permeation/Penetration through Bovine C…

2021

Ophthalmic drug delivery is still a challenge due to the protective barriers of the eye. A common strategy to promote drug absorption is the use of ocular permeation enhancers, while an innovative approach is the use of polymeric micelles. In the present work, the two mentioned approaches were coupled by conjugating ocular permeation enhancers (PEG2000, carnitine, creatine, taurine) to an inulin-based co-polymer (INU-EDA-RA) in order to obtain self-assembling biopolymers with permeation enhancer properties for the hydrophobic drug dexamethasone (DEX). Inulin derivatives were properly synthetized, were found to expose about 2% mol/mol of enhancer molecules in the side chain, and resulted abl…

permeation enhancermicellesPEG2000InulinPharmaceutical SciencedexamethasoneMicelleocular drug deliveryArticlechemistry.chemical_compoundPharmacy and materia medicaSide chainEnhancerChromatographyinulinPEG<sub>2000</sub>Chemistrypermeation enhancerscarnitinePenetration (firestop)PermeationRS1-441creatineIonic strengthtaurineEx vivoPharmaceutics
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Non-Occupational Exposure to Pesticides: Experimental Approaches and Analytical Techniques (from 2019)

2021

© 2021 by the authors.

pesticide residuesNon occupationalenvironmental exposurePharmaceutical ScienceOrganic chemistryReview010501 environmental scienceshuman health01 natural sciencesGas Chromatography-Mass SpectrometryMass SpectrometryAnalytical ChemistryGlobal populationHuman healthQD241-441Environmental healthDrug DiscoveryPlaguicidesHealth Status IndicatorsHumansPesticidesPhysical and Theoretical ChemistrySolvent extractionestimated intakesChromatography High Pressure Liquid0105 earth and related environmental sciencesPesticide residueSolid Phase Extraction010401 analytical chemistryindirect estimationdirect estimationEnvironmental exposureQuímicaPesticide0104 chemical scienceswastewater-based epidemiologyChemistry (miscellaneous)Human exposureSolventsMolecular MedicineEnvironmental scienceMolecules
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