Search results for "42"
showing 10 items of 3911 documents
Protective potential of glucagon like peptide 2 (GLP-2) against the neurodegeneration
2019
Neurodegeneration consists in loss of neuron specific types, pattern and distribution, leading to progressive dysfunctions of the central nervous system. Neurodegenerative diseases include diverse pathological conditions, among which Alzheimer’s and Parkinson’s diseases are the most prevalent ones. Alzheimer’s disease is known as a growing dementia, characterized by progressive language, memory, and cognitive loss, while Parkinson’s disease is primarily characterized as a motor disorder. Senile plaques, caused by amyloid β peptide, hyperphosphorylated tau-based neurofibrillary tangles and synapse loss, are the principal pathological hallmarks of Alzheimer’s disease. Amyloid β oligomer forma…
Family carers and lack of personal time: Descriptions of being outside the sphere of formal help
2011
The aim of this article is to study manifestations of uncomfortable familial commitments. The connection of such commitments to informal family carers' descriptions of problems in accessibility of services and to descriptions of preferences regarding limited use of formal help is examined. The data consists of 21 qualitative interviews of Finnish persons who, alongside their gainful employment, cared for their parent(s). It is argued that the lives of adult children and parent(s) needing care and help are interdependent, and various uncomfortable familial commitments exist due to problems in service provision (accessibility of services) or the reluctance of parents to accept formal help (us…
Cost analysis of the first two year of universal mass vaccination against rotavirus in Sicily
2015
Background Rotavirus vaccination (RV) is recognized by international health authority as the best strategy to prevent rotavirus gastroenteritis (RVGE) in children. Costs of RVGE were estimated in several studies and were classified into direct and indirect costs, that should be further divided into Health care and social perspective. This study aims to evaluate RVGE hospitalization costs in Sicily, before and after universal mass RV (UMRV) introduction. Methods Cases of RVGE were defined as all hospitalizations with an ICD-9-CM diagnosis code of 008.61 on any diagnosis position among children aged 0 to 59 months. Data were obtained from Hospital discharge records (HDR) of the Health Regiona…
Editorial: Pathophysiologic Insights From Biomarker Studies in Neurological Disorders
2020
In 2014 cancer registration covers more than half of the Italian population [Nel 2014 la registrazione dei tumori in Italia è estesa a oltre la metà …
2014
After the increasing trend in the Nineties, in Italy incidence of tumours in children (0-14 years) is decreasing [Dopo l'aumento registrato negli ann…
2014
About 1,400 new cancer diagnosis in Italian children (0-14 years) are attended every year (7,000 in 5 years) [Ogni anno sono previste circa 1.400 nuo…
2013
Comparison of paediatric cancers outcomes between Palermo Province (Sicily) and Southern Europe
2018
Background: Italy has one of the highest paediatric cancer incidence rate in Europe. We compared cancer incidence and survival in children (0-14 years) and adolescents (15-19 years) resident in Palermo Province with statistics derived from Italian and European surveillance systems. Methods: We included all incident cancer cases, malignant tumours and non-malignant neoplasm of central nervous system (benign and uncertain whether malignant or benign), detected in children and adolescents by the Palermo Province Cancer Registry between 2003 and 2012. A joinpoint regression model was applied. Annual Average Percentage Changes were calculated. The Besag–York–Mollie model was used to detect any c…