Search results for "44"
showing 10 items of 1507 documents
Lamentos al son del arpa. La imagen del rey David penitente en la pintura valenciana del Barroco
2015
Este artículo parte de dos lienzos de Pablo Pontons y Vicente Guilló para el estudio de la imagen del rey David, especialmente en su tipo iconográfico de David penitente. Formulado originalmente en las miniaturas medievales que se apoyaban en su papel de salmista y fundador de la música sacra, esta tipología tomó episodios de su vida que se convirtieron en modelos de penitencia. El trabajo estudia la tradición cultural convencionalizada de la gura de David, su patronazgo musical y la continuidad del tipo del rey penitente en el Barroco, tanto en grabados como en programas visuales como los de Pontons y Guilló para Morella y Alcalà de Xivert, respectivamente. Este uso didáctico per…
THE OLIGARCH AND THE PAINTBRUSHES: A BIOGRAPHICAL SKETCH OF ANDREU GARCIA, PRIEST = EL OLIGARCA Y LOS PINCELES: BREVE SEMBLANZA DEL PRESBÍTERO ANDREU…
2014
The documents regarding the Valencian priest Andreu Garcia († November 1452) show a quite interesting character. Garcia’s family belonged to local oligarchy. Moreover, he had a substantial income related with the Cathedral. He had contact, too, with Carthusians, Observant Friars and probably with Beghards (the books of his library suggest this last idea). Garcia took part, as an intermediary or as a sponsor, in many artistic orders that involved the best workers and the best customers of the city. Besides, he had a strong relationship with painters like Simó Llobregat, Jaume Mateu, Gonçal Sarrià and Joan Reixac. The priest could also have practiced painting, judging by the belongings that w…
Pervivencia de motivos islámicos en el Renacimiento: El lema «ʼIzz Li-Mawlānā Al-Sulṭān» en las puertas del retablo mayor de la catedral de Valencia …
2018
El aprecio que se tuvo por los tejidos islámicos desde el Medievo es patente en la pintura religiosa. A través de estas líneas se analiza la pervivencia de motivos ornamentales en el Renacimiento, en concreto, el uso de letras árabes a partir del estudio de tres escenas de las puertas del retablo mayor de la catedral de Valencia pintadas por los Hernandos. En ellas los maestros copiaron un tejido nazarí con una inscripción cuya traducción ha pasado inadvertida hasta este momento y que plantea distintas hipótesis sobre su utilización en la obra.The appreciation of Islamic textiles since the Middle Ages is evident in religious painting. The aim of this paper is to analyze the survival of orna…
Abstract 3056: Lung tumor spheres as in vitro platform for testing new therapeutic strategies against cancer stem cells
2018
Abstract Background: Treatment resistance is related to cancer stem cells (CSCs), a highly tumorigenic subpopulation of cells capable of growing and forming tumor spheres under non-adherent conditions. This study aimed to isolate and characterise CSCs from resected non-small cell lung cancer (NSCLC) patients' tumor-tissue and cell lines like tumor spheres and to use them as an in vitro platform for drug screening. Methods: The study was performed on tumour cells from 8 resected NSCLC patients and 12 NSCLC cell lines grown in monolayer and as spheres. The expression of 60 genes, including CSC-markers, pluripotency inducers, cell cycle regulators and components of the Notch, Wnt and Hedgehog …
Abstract 3354: Characterization of lung tumorspheres by gene expression and flow cytometry: differential expression in CSC-related markers and signal…
2016
Abstract Chemoresistance, progression and metastasis have made of lung cancer the first cause of cancer mortality. These features were linked to a subpopulation of cells, named cancer stem cells (CSCs), which remain largely unknown. The aim of this study was to isolate and characterize CSCs from lung cancer cell-lines and tumor-tissue from resectable non-small cell lung cancer (NSCLC). Methods: Tumor cells from resected NSCLC and cell lines (H1650, H1993, A549, and PC9) were grown in monolayer and as spheroids. RTqPCR was performed to analyze the mRNA expression of CSCs-related genes: CSC-markers (EPCAM1, ALDH1A1, CD166, ABCG2, CD44, CD133); pluripotency genes (KLF4, OCT4, NANOG, SOX2, MYC,…
A Stereocontrolled Protocol to Highly Functionalized Fluorinated Scaffolds through a Fluoride Opening of Oxiranes
2016
A novel selective and substrate-dependent synthetic protocol has been developed towards the synthesis of various fluorine-containing, highly functionalized cycloalkane derivatives. The method involves the stereoselective epoxidation of some unsaturated cyclic beta-amino acid derivatives as model compounds, followed by a regioselective fluoride opening of oxiranes under various conditions with Deoxofluor and XtalFluor-E reagents, thereby offering an insight into this new epoxide opening methodology with fluoride.
Conformational equilibrium in supramolecular chemistry: Dibutyltriuret case
2015
The association of substituted benzoates and naphthyridine dianions was used to study the complexation of dibutyltriuret. The title molecule is the simplest molecule able to form two intramolecular hydrogen bonds. The naphthyridine salt was used to break two intramolecular hydrogen bonds at a time while with the use of substituted benzoates the systematic approach to study association was achieved. Both, titrations and variable temperature measurements shed the light on the importance of conformational equilibrium and its influence on association in solution. Moreover, the associates were observed by mass spectrometry. The DFT-based computations for complexes and single bond rotational barr…
Factors Affecting Polyphenol Biosynthesis in Wild and Field Grown St. John’s Wort (Hypericum perforatum L. Hypericaceae/Guttiferae)
2009
The increasing diffusion of herbal products is posing new questions: why are products so often different in their composition and efficacy? Which approach is more suitable to increase the biochemical productivity of medicinal plants with large-scale, low-cost solutions? Can the phytochemical profile of a medicinal plant be modulated in order to increase the accumulation of its most valuable constituents? Will polyphenol-rich medicinal crops ever be traded as commodities? Providing a proactive answer to such questions is an extremely hard task, due to the large number of variables involved: intraspecific chemodiversity, plant breeding, ontogenetic stage, post-harvest handling, biotic and abi…
Training programme for novice physical activity instructors using Teaching Personal and Social Responsibility (TPSR) model : a programme development …
2021
Previous research indicates that programmes employing Hellison?s Teaching Personal and Social Responsibility (TPSR) model in physical activity have had a positive impact on youth development by increasing participants? positive values, autonomy, life skills, and prosocial behaviour. Despite encouraging results of the effects of TPSR-based programmes, there remains lack of research on the effective content of these programmes, and their implementation and evaluation. The current protocol article describes the development of a TPSR-based instructor training programme and a plan for an intervention study in which novice instructors learn to understand and apply the TPSR model in practice. The …
Negative and positive feedback from a supernova remnant with SHREC
2022
Supernova remnants (SNRs) contribute to regulate the star formation efficiency and evolution of galaxies. As they expand into the interstellar medium (ISM), they transfer vast amounts of energy and momentum that displace, compress and heat the surrounding material. Despite the extensive work in galaxy evolution models, it remains to be observationally validated to what extent the molecular ISM is affected by the interaction with SNRs. We use the first results of the ESO-ARO Public Spectroscopic Survey SHREC, to investigate the shock interaction between the SNR IC443 and the nearby molecular clump G. We use high sensitivity SiO(2-1) and H$^{13}$CO$^+$(1-0) maps obtained by SHREC together wit…