Search results for "45"
showing 10 items of 1896 documents
A prototypal architecture of a IEEE 21451 network for smart grid applications based on power line communications
2015
This paper deals with the development of reliable measurement and communication devices and systems and their integration on a prototypal network architecture for smart grid applications, based on the use of narrowband power line communications (PLCs). The proposed solution is presented and discussed in the framework of the ISO/IEC/IEEE 21451 family of Standards. Currently, PLCs are not properly addressed by the aforesaid Standards; on the other hand, by including such issue, their guidelines could represent a common platform for the integration and interoperability of the proposed systems and devices. This would allow to exploit the benefits of the IEEE 21451 approach also for PLC-based sm…
Apoptotic activity of isoespintanol derivatives in human polymorphonuclear cells
2016
Background: Inflammation is a complex physiopathologic response to different stimuli. Recently, some pharmacological strategies have been proposed that could be used for resolution of inflammation by enhancing apoptosis of inflammatory cells. Objectives: To study in vitro apoptotic activity of isoespintanol [ISO] and of two semi-synthetic derivatives, bromide isoespintanol [BrI] and demethylated isoespintanol [DMI], in human polymorphonuclear (PMN) cells. Methods: PMN were exposed to the different concentrations of ISO, BrI and DMI for 30 min in phosphate-buffered saline pH 7.4 containing 1 mg/mL glucose, 0.4 mM Mg2+, and 1.20 mM Ca2+. Viability was assessed by dimethylthiazol diphenyl tetr…
Expression and inducibility of drug-metabolizing enzymes in preneoplastic and neoplastic lesions of rat liver during nitrosamine-induced hepatocarcin…
1987
The expression, inducibility, and regulation of four different cytochrome (cyt.) P-450 isoenzymes (PB1, PB2, MC1, and MC2) NADPH-cytochrome P-450 reductase, the glutathione transferases (GSTs) B and C and microsomal epoxide hydrolase (mEHb) have been studied during nitrosamine-induced hepatocarcinogenesis using immunohistochemical techniques. The investigations revealed basic differences in the expression of the individual drug metabolizing enzymes in the course of neoplastic development. While the two GSTs and mEHb were increased in all preneoplastic and benign neoplastic lesions, the levels of the distinct cyt. P-450 isoenzymes were characteristically different from each other. Following …
Modulation of mutagenicity by phosphorylation of mutagen-metabolizing enzymes.
2004
In this Minireview, we discuss our findings on phosphorylation of cytochromes P450 (CYP) and influence of this modification on metabolic toxification and/or detoxification of a variety of mutagens. We show that phosphorylation drastically interferes with the mutagenicity of several classes of compounds which are of high human relevance (cytostatic drugs of the cyclophosphamide type, aromatic amines/amides, and nitrosamines). We illustrate this by describing the consequences of the stimulation of protein kinase A (with the example of CYP2B1 and CYP2E1), stimulation of protein kinase C, and inhibition of protein phosphatases PP1 and PP2A (with the example of CYP1A1 and CYP1A2). We discuss a p…
Existence and uniqueness of nontrivial collocation solutions of implicitly linear homogeneous Volterra integral equations
2011
We analyze collocation methods for nonlinear homogeneous Volterra-Hammerstein integral equations with non-Lipschitz nonlinearity. We present different kinds of existence and uniqueness of nontrivial collocation solutions and we give conditions for such existence and uniqueness in some cases. Finally we illustrate these methods with an example of a collocation problem, and we give some examples of collocation problems that do not fit in the cases studied previously.
Advances in photonic reservoir computing
2017
We review a novel paradigm that has emerged in analogue neuromorphic optical computing. The goal is to implement a reservoir computer in optics, where information is encoded in the intensity and phase of the optical field. Reservoir computing is a bio-inspired approach especially suited for processing time-dependent information. The reservoir’s complex and high-dimensional transient response to the input signal is capable of universal computation. The reservoir does not need to be trained, which makes it very well suited for optics. As such, much of the promise of photonic reservoirs lies in their minimal hardware requirements, a tremendous advantage over other hardware-intensive neural net…
Observation of charmonium pairs produced exclusively in $pp$ collisions
2014
A search is performed for the central exclusive production of pairs of charmonia produced in proton-proton collisions. Using data corresponding to an integrated luminosity of $3{\rm\ fb}^{-1}$ collected at centre-of-mass energies of 7 and 8 TeV, $J/\psi J/\psi$ and $J/\psi\psi(2S)$ pairs are observed, which have been produced in the absence of any other activity inside the LHCb acceptance that is sensitive to charged particles in the pseudorapidity ranges $(-3.5,-1.5)$ and $(1.5,5.0)$. Searches are also performed for pairs of P-wave charmonia and limits are set on their production. The cross-sections for these processes, where the dimeson system has a rapidity between 2.0 and 4.5, are measu…
Le fonds Schneider et compagnie dans la grande guerre
2018
National audience; Intervention dans le cadre d'un colloque organisé par l’Académie François Bourdon, la Maison des Sciences de l’Homme de Dijon, la mission histoire de la Société Générale et le réseau Archives numériques des mondes contemporains.
Correlation between Work Engagement and Burnout among Registered Nurses: an Italian hospital survey
2019
AIM: To investigate the correlation between work engagement and burnout among Italian nurses. INTRODUCTION: Work engagement is a protective factor against burnout. Both of them may be affected by the cultural and organizational features of the investigated population, which means that results cannot be generalized. In Italy studies to measure how they correlate have never been performed. METHODS: Monocentric and quantitative observational study. The Maslach Burnout Inventory and the Utrecht Work Engagement Scale were used on a convenience sample of 318 nurses from an Italian hospital to assess the burnout and work engagement levels and to measure the existing correlation between the two con…
METAGENOMIC ANALYSIS OF PHYTOPHTHORA DIVERSITY IN NURSERIES OF POTTED ORNAMENTAL SPECIES.
2015
The genetic diversity of Phytophthora was investigated in soil and root samples of potted ornamental and fruit tree plants collected in nurseries located in Apulia and Calabria (Southern Italy) using metagenomic approaches based on Phytophthora genus specific primers. PCR amplicons containing the ITS1 region of the rDNA were sequenced using both a conventional cloning and Sanger sequencing approach and a 454 pyrosequencing protocol. All sequences were accurately analyzed with an appropriate software and used as barcode for species identification utilizing a validated ITS database. The cloning/Sanger sequencing approach enabled the identification of nine different Phytophthora taxa (P. nicot…