Search results for "45"
showing 10 items of 1896 documents
Tres artistas en el exilio: Max Aub, Félix Candela y Josep Renau
2020
Three artists in exile focuses on the historical diaspora provoked by the Spanish civil war (1936- 1939), and how it influenced three prominent figures of the cultural scene of that period: the writer and typographer Max Aub Mohrenwitz (Paris, 1903-Ciudad de Mexico, 1972); the architect Félix Candela Outeriño (Madrid, 1910-Raleigh, US, 1977); and the artist Josep Renau Berenguer (Valencia, 1907-Berlín, 1982). They are the three protagonists of this article, who were simultaneously living in Mexico during the exile and who made notable contributions in the fields of arts and humanities (Max Aub), architecture (Félix Candela), and graphic design and photomontage (Josep Renau). While they were…
Cytochrome P450 1A- and stress protein-induction in early life stages of medaka (Oryzias latipes) exposed to trichloroethylene (TCE) soot and differe…
2013
It has previously been shown that trichloroethylene (TCE) soot extracts cause dioxinlike toxic effects in medaka fish (Oryzias latipes) and primary liver cell culture of rainbow trout (Oncorhynchus mykiss). This study examines embryonic and larval induction of cytochrome P450 1A and stress proteins after exposure of medaka embryos to extracts and fractions of TCE combustien-generated aerosols. Embryos were exposed to three concentrations of whole soot extract (WE; 2.7, 7.2 and 18 μg l -1 incomplete combustion by-products), TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin, 3 ng l -1 ) and four TCE fractions with different polarity (Fr 1-4; 18 μg l -1 ) for 8 days. Approximately 50% of the embryos w…
Bresaola made from Cinisara cattle: effect of muscle type and animal category on physicochemical and sensory traits
2020
The physicochemical characteristics and sensory traits of Cinisara bresaola were investigated, to explore a new commercial opportunity for autochthonous dairy cattle farms. Semimembranosus, Semitendinosus and Biceps brachii muscles, from adult cows (AC) and grazing (GB) or housed (HB) young bulls of Cinisara breed, were processed to made bresaola. Differences due to animal category and muscle type were observed. Bresaola from AC was richer in fat and volatile organic compounds. The bresaola from Semitendinosus showed higher colorimetric parameters, fat and, when from grazing animals, Warner-Bratzler shear force than those made from other muscles. In general, all bresaola were well appreciat…
El papel de la sociología en el ámbito del desarrollo local: aportaciones tras dos décadas de experiencia en la administración pública
2021
Grandir après la Shoah : l'histoire méconnue de ces juifs communistes qui accueillirent des enfants de déportés
2015
International audience
Mamá Antula: la beata de los ejercicios espirituales desde la mirada de los jesuitas desterrados
2016
Resumen: Cuando en 1767 Carlos III expulsó a los jesuitas, una beata: Mª Antonia de San José, asumió la responsabilidad de continuar con la labor de estos religiosos, centrándose en la realización de los Ejercicios Espirituales al modo de San Ignacio por la Provincia de Paraguay. Analizamos aquí la influencia de estos jesuitas en su actividad misional y algunos de los comentarios que hicieron durante su exilio. Palabras clave: jesuitas, beata, ejercicios espirituales, destierro Abstract: When in 1767 Charles III of Spain expelled the Jesuits, a devout woman: Maria Antonia de San José, continued their work focusing on the realization of the Ignatian Spiritual Exercises along the Province of …
The solubilization site of 5,10,15,20-tetrakis-(2,6-dichlorophenyl)-porphyrin-Mn(III) in DPPC vesicles: A spectrophotometric and tensiometric study
2006
The solubilization site of 5,10,15,20-tetrakis-(2,6-dichlorophenyl)-porphyrin-Mn(III) (MnTDPPC) in (L)-alpha-dipalmitoylphosphatidyl choline (DPPC) vesicles was determined in a systematic UV-vis spectrophotometric study. Measurements of the MnTDPPC absorbance have been conducted at constant temperatures (in the interval 30 degrees C <= T <= 48 degrees C) and varying concentrations of phospholipid. In the entire temperature range, the absorption due to MnTDCCP was found to increase with increasing DPPC concentration, until it reaches a plateau value. The data have been analyzed using a pseudo-phase model yielding the binding constant of MnTDCPP to vesicular aggregates. No significant tempera…
Dietary polyphenols as antidiabetic agents: Advances and opportunities
2020
Abstract Dietary polyphenols have been widely investigated as antidiabetic agents in cell, animals, human study, and clinical trial. The number of publication (Indexed by Web of Science) on “polyphenols and diabetes” significantly increased since 2010. This review highlights the advances and opportunities of dietary polyphenols as antidiabetic agents. Dietary polyphenols prevent and manage Type 2 diabetes mellitus via the insulin‐dependent approaches, for instance, protection of pancreatic islet β‐cell, reduction of β‐cell apoptosis, promotion of β‐cell proliferation, attenuation of oxidative stress, activation of insulin signaling, and stimulation of pancreas to secrete insulin, as well as…
An in vitro tool to assess cytochrome P450 drug biotransformation-dependent cytotoxicity in engineered HepG2 cells generated by using adenoviral vect…
2011
Many adverse drug reactions leading to hepatotoxicity are caused by the cytochrome P450-dependent activation of non-toxic drugs or chemicals into reactive metabolites. To this end, adenoviruses were used as a tool to efficiently deliver specific CYP genes into cultured cells (i.e., human hepatoma cell line HepG2). Recombinant-defective adenoviral vectors encoding for genes CYP3A4 (Adv-CYP3A4), CYP2E1 (Adv-CYP2E1), CYP2A6 (Adv-CYP2A6) and CYP1A2 (Adv-CYP1A2) were used to confer specific CYP drug metabolic capabilities to HepG2 cells. Upgraded cells transiently expressed single specific cytochrome P450 enzymatic activities in terms of the number of the infecting virus particles used in their …
Triterpenoid saponins from Polycarpaea corymbosa Lamk. var. eriantha Hochst.
2013
Abstract Four triterpenoid saponins (1–4) were isolated from Polycarpaea corymbosa Lamk. var. eriantha Hochst along with the known apoanagallosaponin IV (5). Their structures were elucidated by spectroscopic data analysis. Among the compounds 1, 3–5 which were evaluated for their cytotoxicity against three tumor cell lines (SW480, DU145 and EMT6), compound 1 exhibited cytotoxicity with IC50 values ranging from 4.61 to 22.61 μM, which was greater than that of etoposide. Compound 2 was tested only against SW480 and a cardiomyoblast cell line (H9c2), and was inactive.