Search results for "45"
showing 10 items of 1896 documents
El uso y consumo de agua en los jardines de las viviendas del litoral de Alicante (España)
2016
El jardín es el elemento que ha adquirido una mayor difusión en los modelos urbanos extensivos en la costa de Alicante (España). En este territorio, a diferencia de otros ámbitos, los jardines unifamiliares se asocian a las urbanizaciones que se han ido configurando desde 1960 a raíz de la expansión del denominado turismo residencial. Los objetivos de esta investigación son identificar las principales características de los jardines unifamiliares y, a partir de ellas, estimar sus necesidades hídricas y determinar el volumen de agua doméstico consumido por el jardín en el hogar. Profundizar en estos factores resulta prioritario para determinar sus repercusiones en la demanda de agua presente…
Nimfes al Vinalopó. La poesia renaixentista d’un alacantí oblidat, Josep Gosalbes de Cunedo (s. XVI)
2013
Resum: L’obra del poeta alacantí del segle XVI Josep Gosalbes de Cunedo ha passat a l’oblit. Alguns aspectes de la seua vida i obra mereixen atenció, com a mínim, per haver tractat temes propis de la seua terra. Alguns dels seus poemes tracten l’antiga Governació d’Oriola, al sud del regne de València, i celebren la creació del bisbat d’Oriola, motiu pel qual l’autor descriu el territori amb gust renaixentista. La seua amistat amb l’humanista Just Lipsi marca la seua biografia, on guerres i presó també estan presents.Paraules clau: poesia llatina; Renaixement; Oriola; Alacant; Just LipsiAbstract: The work of the 16th. century poet from Alicante Joseph Gosalbes of Cunedo has been forgotten. …
Asthma, allergies and respiratory symptoms in different activity groups of swimmers exercising in swimming halls
2021
Abstract Background Respiratory symptoms are common in competitive swimmers. However, among these and in swimmers at other activity levels the swimming distance, the total spent time in swimming halls and their medical background varies. Our objectives were, first, to assess their medical histories and the associations with respiratory symptoms among swimmers in different activity groups and then second, to study the pulmonary function findings and related medications in competitive swimmers who exercise in swimming hall environments the most. Methods First, 1118 participants consisting of 133 competitive-, 734 fitness- and 251 occasional swimmers answered questionnaires concerning their me…
Elogio de el Exc.mo y rever.mo señor Don Francisco de Almeida Mascareñas Principal de la Santa Iglesia Patriarchal de Lisboa ...
Accion de gracias a la Sabiduria Divina, tutelar de la Academia Valenciana / que ... se leyó en nombre de D. Francisco de Almeida y Mascareñas ...: p. 27-41 Alg. caplletra orn., fris tip., vinyeta a la port Sign.: A-F4, [ ]1. - Reclams
Studi greci e latini nell?antica Università di Altamura (1748-1821)
2019
The article tries to highlight, despite the scarse of available documentation, the Greek and Latin studies (language and texts) in the ancient Apulian University in Altamura (1748-1821). Furthermore, on the basis of unpublished archival materials (school registers and student workbooks) it is possible to shed light on the ancient authors explained at school, the teaching methods, and the study practices.
"Un puente sobre el abismo", de Higinio Noja Ruiz (1932) : cultura libertaria y literatura pacifista de entreguerras
2021
El escritor, ensayista y militante anarquista Higinio Noja Ruiz publicó en 1932 la novela Un puente sobre el abismo en la Editorial Estudios de Valencia. En ella Noja abordó el tema de las guerras y la lucha contra ellas a través de su protagonista, Guillermo Arjona, un joven burgués mallorquín muy influido por su lectura de las novelas sobre la Primera Guerra Mundial y casi obsesionado con esta temática. Se analiza aquí en primer lugar la figura de Noja Ruiz (1994-1972), prolífico novelista social a la vez que ensayista y pensador libertario de las décadas de 1920 y 1930. La trayectoria de Noja es inseparable de la de la revista cultural y editorial libertaria valenciana Estudios (1928-193…
Chronic Non-cancer Pain Management in a Tertiary Pain Clinic Network: a Retrospective Study
2022
Introduction: Chronic pain is a distressing condition that should be treated in specialized pain clinics. Pain clinics offer a holistic, evidence-based approach, including pharmacological, complementary, and invasive treatments. This study aimed to provide preliminary information regarding chronic pain treatments and identify reasons for accessing an important hub-spoke pain clinic network. Methods: A retrospective multicenter cross-sectional study was carried out. A total of 1606 patients’ records were included. Patients were selected from the 26 pain clinics of a single region in Italy. Univariate and multivariate logistic regression models were used. Results: Multivariate models showed t…
Human Hepatic Cell Cultures: In Vitro and In Vivo Drug Metabolism
2003
Drug metabolism is the major determinant of drug clearance, and the factor most frequently responsible for inter-individual differences in drug pharmacokinetics. The expression of drug metabolising enzymes shows significant interspecies differences, and variability among human individuals (polymorphic or inducible enzymes) makes the accurate prediction of the metabolism of a new compound in humans difficult. Several key issues need to be addressed at the early stages of drug development to improve drug candidate selection: a) how fast the compound will be metabolised; b) what metabolites will be formed (metabolic profile); c) which enzymes are involved and to what extent; and d) whether dr…
In vitro Antifungal Activity of Biopolymeric Foam Activated with Carvacrol
2020
Background: Active packaging represents a defining strategy to improve food quality and safety of the packaged foods. This study aimed to evaluate the in vitro ability of commercial biopolymeric foams, namely Mater-Bi (MB), activated with 20% of carvacrol, to develop a completely biodegradable and compostable packaging to inhibit the growth of spoilage and pathogenic yeasts.
 Methods: MB foams, with and without carvacrol, were produced by melt mixing and the foaming process was performed in a laboratory press. The antifungal activity of foams containing carvacrol was tested applying the disk diffusion method. Statistical analysis was done using XLStat software version 7.5.2 for Excel.&…
Recent advances in computational design of potent aromatase inhibitors: open-eye on endocrine-resistant breast cancers.
2019
Introduction: The vast majority of breast cancers (BC) are estrogen receptor positive (ER+). The most effective treatments to fight this BC type rely on estrogen deprivation therapy, by inhibiting the aromatase enzyme, which performs estrogen biosynthesis, or on blocking the estrogens signaling path via modulating/degrading the estrogen's specific nuclear receptor (estrogen receptor-?, ER?). While being effective at early disease stage, patients treated with aromatase inhibitors (AIs) may acquire resistance and often relapse after prolonged therapies. Areas covered: In this compendium, after an overview of the historical development of the AIs currently in clinical use, and of the computati…