Search results for "47"
showing 10 items of 1382 documents
Don Alons de Cardona i Borja (1600-1659). Primer marq´`es de Castellnou. Família, patrimoni i política
2017
El privilegio del saber. Juristas en los reinos de Valencia y Portugal (siglos XVI-XVII)
2021
Familiares de la inquisición portuguesa (siglos XVI-XVII): los números, la demanda y los grupos sociales intermedios
2021
Ramírez Aledón, Germán: La Ilustración católica ante la crisis del Antiguo Régimen en España. Joaquín Lorenzo Villanueva y Astengo
2021
Cine y música: : sobre la consubstancialidad de las artes y el diálogo
2013
Festival Nits d'Aielo i Art. Consideraciones de pasado, presente y ¿futuro?
2014
Incorporaciones de obras de arte a las colecciones de la Real Academia de Bellas Artes de San Carlos, 2015-2016
2016
A population genomics analysis of the native Irish Galway sheep breed.
2019
SUMMARYThe Galway sheep population is the only native Irish sheep breed and represents an important livestock genetic resource, which is currently categorised as “at-risk”. In the present study, comparative population genomics analyses of Galway sheep and other sheep populations of European origin were used to investigate the microevolution and recent genetic history of the breed. These analyses support the hypothesis that British Leicester sheep were used in the formation of the Galway breed and suggest more recent gene flow from the Suffolk sheep breed. When compared to conventional and endangered breeds, the Galway breed was intermediate in effective population size, genomic inbreeding a…
Computational processing and quality control of Hi-C, capture Hi-C and capture-C data
2019
Hi-C, capture Hi-C (CHC) and Capture-C have contributed greatly to our present understanding of the three-dimensional organization of genomes in the context of transcriptional regulation by characterizing the roles of topological associated domains, enhancer promoter loops and other three-dimensional genomic interactions. The analysis is based on counts of chimeric read pairs that map to interacting regions of the genome. However, the processing and quality control presents a number of unique challenges. We review here the experimental and computational foundations and explain how the characteristics of restriction digests, sonication fragments and read pairs can be exploited to distinguish…
Consequences of single-locus and tightly linked genomic architectures for evolutionary responses to environmental change
2020
AbstractGenetic and genomic architectures of traits under selection are key factors influencing evolutionary responses. Yet, knowledge of their impacts has been limited by a widespread assumption that most traits are controlled by unlinked polygenic architectures. Recent advances in genome sequencing and eco-evolutionary modelling are unlocking the potential for integrating genomic information into predictions of population responses to environmental change. Using eco-evolutionary simulations, we demonstrate that hypothetical single-locus control of a life history trait produces highly variable and unpredictable harvesting-induced evolution relative to the classically applied multi-locus mo…