Search results for "49"
showing 10 items of 1208 documents
Propositio facta per oratores Innocentii VIII coram Carolo VIII, Francorum rege
1488
Sign.: a6. - Data completa, d. 20 gener, 1488 L. gòt. - 33 lín. - Capll. grav
Renal function and carotid atherosclerosis in adults with no known kidney disease
2017
Abstract Background and aims A high prevalence of atherosclerotic lesions characterizes patients with chronic kidney disease, though there is little data on the relationship between kidney function and atherosclerotic changes in the healthy population or in people with no known renal impairment. The aim of our study was to analyze, in a comprehensive general population with no known kidney disease, the relationship between renal function and subclinical carotid atherosclerotic damage. Methods and results A general real-life population of 611 participants (233 males and 378 females; age ≥18 years) with no known kidney failure was selected for the study. The glomerular filtration rate (GFR) w…
Habitual street food intake and subclinical carotid atherosclerosis.
2013
Street food (SF) is defined as out-of-home food consumption, and generally consists of energy-dense meals rich in saturated fats and poor in fibers, vitamins and antioxidants. Though SF consumption may have unfavorable metabolic and cardiovascular effects, its possible association with atherosclerosis has not been considered. The association between habitual SF consumption and asymptomatic carotid atherosclerosis, defined as the presence of plaques and/or increased intima-media thickness, was therefore investigated. One thousand thirty-five randomly selected adult participants without known diabetes and atherosclerotic cardiovascular diseases were cross-sectionally investigated in Palermo, …
Socializing makes thick-skinned individuals: on the density of epidermal alarm substance cells in cyprinid fish, the crucian carp (Carassius carassiu…
2010
Published version of an article in the journal: Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology. Also available on SpringerLink: http://dx.doi.org/10.1007/s00359-010-0550-4 In cyprinid fish, density of epidermal club cells (i.e. alarm substance cells) has been found to vary between lakes with different predator fauna. Because predators can be labelled with chemical cues from prey, we questioned if club cell density could be controlled indirectly by predators releasing prey cues. In particular, we suspected a possible feedback mechanism between chemical alarm signals and their cellular source. We raised crucian carp singly and in groups of four.…
Coñece-lo mundo baixomedieval hispánico a través dos seus refráns: Los refranes que dizen las viejas tras el fuego
2011
O obxectivo do presente artigo é destacar brevemente algúns aspectos socioculturais, políticos e económicos da baixa Idade Media do reino de Castela (e, por extensión, nalgúns casos, dos restantes reinos cristiáns peninsulares), extraíbles da fosilización formal de enunciados pluriverbais que coñecemos como refráns. Baséase, primeiro, na consideración do refrán como reflexo, en maior ou menor medida, da sociedade do seu tempo (e tamén de épocas anteriores) e, segundo, como depositario non só do saber tradicional que se transmite de xeración en xeración, senón tamén da cultura socioeconómica, material e ambiental de épocas pretéritas. Para iso emprégase como corpus textual os Refranes que di…
In vitro impact preliminary assessment of airborne particulate from metalworking and woodworking industries.
2020
Abstract BackgroundInhalation is the main route of exposure to airborne pollutants. To evaluate the safety and assess the risks of occupational hazards different testing approaches are used. 3D airway epithelial tissues allow to mimic exposure conditions in vitro, generates human-relevant toxicology data, allows to elucidate mode of action of pollutants. ResultsGilian 3500 pumps equipped with Standard Midget Impingers were used to collect the airborne particulate from woodworking and metalworking environments. EpiAirway™ tissues were used to model half working day (4 h), full working day (8 h), and 3 working day exposures to occupational pollutants. Tissue viability was assessed using MTT a…
The MDM2-p53 pathway is involved in preconditioning-induced neuronal tolerance to ischemia
2018
Brain preconditioning (PC) refers to a state of transient tolerance against a lethal insult that can be evoked by a prior mild event. It is thought that PC may induce different pathways responsible for neuroprotection, which may involve the attenuation of cell damage pathways, including the apoptotic cell death. In this context, p53 is a stress sensor that accumulates during brain ischemia leading to neuronal death. The murine double minute 2 gene (MDM2), a p53-specific E3 ubiquitin ligase, is the main cellular antagonist of p53, mediating its degradation by the proteasome. Here, we study the role of MDM2-p53 pathway on PC-induced neuroprotection both in cultured neurons (in vitro) and rat …
Preventing early age chloride migration into low-carbon concrete
2019
The use of substituting cementitious materials (SCMs) to produce low-carbon concrete is escalating. This contributes to reducing the anthropogenic emission of CO2, and to reduce harmful temperature gradients during cement hydration in massive structures. Mature low-carbon concretes are known to perform well on both strength and durability. However, the maturity process is slow compared to that of standard concrete. Structures made from low-carbon concrete are subject to penetration of agents like chloride at early age, accelerating degrading processes. Chloride penetration is a major problem especially to infrastructure, due to seawater proximity and the use of de-icing agents. Solutions fo…
Ultrastiff graphene
2021
Graphene has exceptionally high in-plane strength, which makes it ideal for various nanomechanical applications. At the same time, its exceptionally low out-of-plane stiffness makes it also flimsy and hard to handle, rendering out-of-plane structures unstable and difficult to fabricate. Therefore, from an application point of view, a method to stiffen graphene would be highly beneficial. Here we demonstrate that graphene can be significantly stiffened by using a laser writing technique called optical forging. We fabricate suspended graphene membranes and use optical forging to create stable corrugations. Nanoindentation experiments show that the corrugations increase graphene bending stiffn…