Search results for "4aR"

showing 10 items of 21 documents

p14ARF re-expression induces apoptosis in aneuploid HCT116 cells

2012

Weakening the Spindle Assembly Checkpoint by reduced expression of its components such as MAD2, BubR1 and MPS1 induces chromosome instability and aneuploidy both hallmarks of cancer cells. p14ARF that is found frequently altered in human cancers, is overexpressed in response to oncogenic stimuli to stabilize p53 halting cell progression. Previously, we determined that lack or reduced expression of p14ARF is involved in the maintenance of aneuploid cells suggesting that it could be part of a pathway controlling proliferation of aneuploidy cells. To investigate further this aspect of p14ARF function it was ectopically expressed in HCT116 cells, a stable near diploid cell line, after MAD2 depl…

Settore BIO/18 - GeneticaMAD2 Aneuploidy P14ARF
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Identification of molecular markers involved in cellular response to aneuploidy in normal and tumor cells

2020

Settore BIO/18 - GeneticaRNA interferenceCENP-EChromosome Instabilityp14ARFMicroarrayAneuploidy
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CCDC 962066: Experimental Crystal Structure Determination

2017

Related Article: Louis P. Sandjo, Eckhard Thines, Till Opatz and Anja Schüffler|2014|Beilstein J.Org.Chem.|10|251|doi:10.3762/bjoc.10.20

Space GroupCrystallographyCrystal SystemCrystal Structure(2E4E)-5-[(1S2S4aR6R8R8aS)-6-hydroxy-268-trimethyl-124a56788a-octahydronaphthalen-1-yl]penta-24-dienoic acidCell ParametersExperimental 3D Coordinates
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CCDC 1899693: Experimental Crystal Structure Determination

2019

Related Article: Maximilian Selt, Stamo Mentizi, Dieter Schollmeyer, Robert Franke, Siegfried R. Waldvogel|2019|Synlett|30|2062|doi:10.1055/s-0039-1690706

Space GroupCrystallographyCrystal SystemCrystal Structure(4aRS9bRS)-44-dichloro-2689b-tetramethyl-4a9b-dihydrodibenzo[bd]furan-3(4H)-oneCell ParametersExperimental 3D Coordinates
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CCDC 795376: Experimental Crystal Structure Determination

2011

Related Article: J.Barjau, G.Schnakenburg, S.R.Waldvogel|2011|Angew.Chem.,Int.Ed.|50|1415|doi:10.1002/anie.201006637

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters(3RS4SR4aRS9bRS)-4a9b-Dihydro-4-(2-hydroxy-35-dimethylphenyl)-4-(24-dimethylphenoxy)-2689b-tetramethyldibenzofuran-3-olExperimental 3D Coordinates
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CCDC 795375: Experimental Crystal Structure Determination

2011

Related Article: J.Barjau, G.Schnakenburg, S.R.Waldvogel|2011|Angew.Chem.,Int.Ed.|50|1415|doi:10.1002/anie.201006637

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters(4RS4aRS9bRS)-4a9b-Dihydro-4-(24-dimethylphenoxy)-4-(2-(1010-dimethylpropionyloxy)-35-dimethylphenyl)-2689b-tetramethyldibenzofuran-3-oneExperimental 3D Coordinates
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CCDC 795379: Experimental Crystal Structure Determination

2011

Related Article: J.Barjau, G.Schnakenburg, S.R.Waldvogel|2011|Angew.Chem.,Int.Ed.|50|1415|doi:10.1002/anie.201006637

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters(5aRS10bRS4aRS15bRS)-13-Dimethoxy-56-dioxa-79121415b17-hexamethyl-(benzo[k]benzo[h]-(benzo[b]furo)[23-b]-[4.3.3]propellan)-16-eneExperimental 3D Coordinates
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CCDC 109406: Experimental Crystal Structure Determination

1999

Related Article: M.Weymann, M.Schultz-Kukula, H.Kunz|1998|Tetrahedron Lett.|39|7835|doi:10.1016/S0040-4039(98)01745-6

Space GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates(2S4aR5R8aR)-N-(2'3'4'6'-Tetra-O-pivaloyl-beta-D-galactopyranosyl)-2-n-propyl-5-methyl-decahydrochinolin-4-one
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CCDC 795377: Experimental Crystal Structure Determination

2011

Related Article: J.Barjau, G.Schnakenburg, S.R.Waldvogel|2011|Angew.Chem.,Int.Ed.|50|1415|doi:10.1002/anie.201006637

Space GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates(4RS4aRS9bRS)-4-Amino-4a9b-dihydro-4-(2-hydroxy-35-dimethylphenyl)-2689b-tetramethyl-dibenzofuran-3(4H)-one
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CCDC 170315: Experimental Crystal Structure Determination

2001

Related Article: A.Abad, C.Agullo, A.C.Cunat, I.Navarro, C.Ramirez de Arellano|2001|Acta Crystallogr.,Sect.E:Struct.Rep.Online|57|o553|doi:10.1107/S1600536801008510

Space GroupCrystallographyCrystal SystemDimethyl(Z)-((8aS2R4aR4bR)-8a-methoxycarbonyl-14a7-trimethyl-8-oxo-2344a4b588a910-decahydro-phenanthren-2-yl)-2-butenedioateCrystal StructureCell ParametersExperimental 3D Coordinates
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