Search results for "4b"
showing 10 items of 72 documents
Complement activation product C4d in oral and oropharyngeal squamous cell carcinoma
2015
OBJECTIVE: Complement C4d-containing fragments have been proposed as diagnostic markers for lung cancer. The purpose of this study was to evaluate the presence of C4d in oropharyngeal (OPSCC) and oral (OSCC) squamous cell carcinomas. SUBJECTS AND METHODS: C4d staining was analyzed by immunohistochemistry in 244 OPSCC surgical specimens. C4d levels were quantified by ELISA in resting saliva samples from 48 patients with oral leukoplakia and 62 with OSCC. Plasma samples from 21 patients with leukoplakia and 30 with oral carcinoma were also studied. RESULTS: C4d staining in OPSCC specimens was associated with nodal invasion (P = 0.001), histopathologic grade (P = 0.014), disease stage (P = 0.0…
Combinatorial Gray codes for classes of pattern avoiding permutations
2007
The past decade has seen a flurry of research into pattern avoiding permutations but little of it is concerned with their exhaustive generation. Many applications call for exhaustive generation of permutations subject to various constraints or imposing a particular generating order. In this paper we present generating algorithms and combinatorial Gray codes for several families of pattern avoiding permutations. Among the families under consideration are those counted by Catalan, Schr\"oder, Pell, even index Fibonacci numbers and the central binomial coefficients. Consequently, this provides Gray codes for $\s_n(\tau)$ for all $\tau\in \s_3$ and the obtained Gray codes have distances 4 and 5.
P-spaces and the Whyburn property
2009
We investigate the Whyburn and weakly Whyburn property in the class of $P$-spaces, that is spaces where every countable intersection of open sets is open. We construct examples of non-weakly Whyburn $P$-spaces of size continuum, thus giving a negative answer under CH to a question of Pelant, Tkachenko, Tkachuk and Wilson. In addition, we show that the weak Kurepa Hypothesis (a set-theoretic assumption weaker than CH) implies the existence of a non-weakly Whyburn $P$-space of size $\aleph_2$. Finally, we consider the behavior of the above-mentioned properties under products; we show in particular that the product of a Lindel\"of weakly Whyburn P-space and a Lindel\"of Whyburn $P$-space is we…
Existence results for parametric boundary value problems involving the mean curvature operator
2014
In this note we propose a variational approach to a parametric differential problem where a prescribed mean curvature equation is considered. In particular, without asymptotic assumptions at zero and at infinity on the potential, we obtain an explicit positive interval of parameters for which the problem under examination has at least one nontrivial and nonnegative solution.
2N+1 highest amplitude of the modulus of the N-th order AP breather and other 2N-2 parameters solutions to the NLS equation
2015
We construct here new deformations of the AP breather (Akhmediev-Peregrine breather) of order N (or AP N breather) with 2N −2 real parameters. Other families of quasi-rational solutions of the NLS equation are obtained. We evaluate the highest amplitude of the modulus of AP breather of order N ; we give the proof that the highest amplitude of the AP N breather is equal to 2N + 1. We get new formulas for the solutions of the NLS equation, different from these already given in previous works. New solutions for the order 8 and their deformations according to the parameters are explicitly given. We get the triangular configurations as well as isolated rings at the same time. Moreover, the appea…
Families of solutions to the CKP equation with multi-parameters
2020
We construct solutions to the CKP (cylindrical Kadomtsev-Petviashvili)) equation in terms of Fredholm determinants. We deduce solutions written as a quotient of wronskians of order 2N. These solutions are called solutions of order N ; they depend on 2N − 1 parameters. They can be written as a quotient of 2 polynomials of degree 2N (N + 1) in x, t and 4N (N + 1) in y depending on 2N − 2 parameters. We explicitly construct the expressions up to order 5 and we study the patterns of their modulus in plane (x, y) and their evolution according to time and parameters.
Wave Propagation in a 3-D Optical Waveguide
2003
In this paper we study the problem of wave propagation in a 3-D optical fiber. The goal is to obtain a solution for the time-harmonic field caused by a source in a cylindrically symmetric waveguide. The geometry of the problem, corresponding to an open waveguide, makes the problem challenging. To solve it, we construct a transform theory which is a nontrivial generalization of a method for solving a 2-D version of this problem given by Magnanini and Santosa.\cite{MS} The extension to 3-D is made complicated by the fact that the resulting eigenvalue problem defining the transform kernel is singular both at the origin and at infinity. The singularities require the investigation of the behavio…
From Fredholm and Wronskian representations to rational solutions to the KPI equation depending on 2N − 2 parameters
2017
International audience; We have already constructed solutions to the Kadomtsev-Petviashvili equation (KPI) in terms of Fredholm determinants and wronskians of order 2N. These solutions have been called solutions of order N and they depend on 2N −1 parameters. We construct here N-order rational solutions. We prove that they can be written as a quotient of 2 polynomials of degree 2N(N +1) in x, y and t depending on 2N−2 parameters. We explicitly construct the expressions of the rational solutions of order 4 depending on 6 real parameters and we study the patterns of their modulus in the plane (x, y) and their evolution according to time and parameters a1, a2, a3, b1, b2, b3.
Hijacking the human complement inhibitor C4b-binding protein by the sporozoite stage of the Plasmodium falciparum parasite
2022
We thank Anna Blom for donating the C4bpα CCP1-2 expression plasmid (pET26-CCP1-2). The following reagent was obtained through BEI Resources, NIAID, NIH: Plasmid pDS56-32/RBSII-CS27IVC-6XHis, MRA-272, contributed by Photini Sinnis. The complement system is considered the first line of defense against pathogens. Hijacking complement regulators from blood is a common evasion tactic of pathogens to inhibit complement activation on their surfaces. Here, we report hijacking of the complement C4b-binding protein (C4bp), the regulator of the classical and lectin pathways of complement activation, by the sporozoite (SPZ) stage of the Plasmodium falciparum parasite. This was shown by direct binding …
$V$-filtrations in positive characteristic and test modules
2013
Let $R$ be a ring essentially of finite type over an $F$-finite field. Given an ideal $\mathfrak{a}$ and a principal Cartier module $M$ we introduce the notion of a $V$-filtration of $M$ along $\mathfrak{a}$. If $M$ is $F$-regular then this coincides with the test module filtration. We also show that the associated graded induces a functor $Gr^{[0,1]}$ from Cartier crystals to Cartier crystals supported on $V(\mathfrak{a})$. This functor commutes with finite pushforwards for principal ideals and with pullbacks along essentially \'etale morphisms. We also derive corresponding transformation rules for test modules generalizing previous results by Schwede and Tucker in the \'etale case (cf. ar…