Search results for "5'"

showing 8 items of 358 documents

Histamine up-regulates phosphodiesterase 4 activity and reduces prostaglandin E2-inhibitory effects in human neutrophils.

2000

Objective: To investigate whether histamine produces up-regulation of phosphodiesterase (PDE) activity with functional consequences in human peripheral blood neutrophils.¶Methods: PDE activity was studied by a radioisotopic method following anion-exchange chromatography. Reverse transcriptase-polymerase chain reaction (RT-PCR) was used for detection of mRNA transcripts of PDE4 subtypes. Cyclic AMP (cAMP) levels were measured by enzyme-immunoassay, and superoxide generation by cytochrome c reduction.¶Treatment: Neutrophils were incubated for 4 h with histamine (1 μM).¶Results: PDE4 was the only isoenzyme activity increased in treated neutrophils. Kinetic analysis showed a ∼1.5-fold increase …

medicine.medical_specialtyTranscription GeneticNeutrophilsImmunologyHeterologousBiologyDinoprostoneNeutrophil Activationchemistry.chemical_compoundPDE4BSuperoxidesInternal medicinemedicineCyclic AMPHumansProtein IsoformsRNA MessengerProstaglandin E2PharmacologyMessenger RNASuperoxideCytochrome cZymosanPhosphodiesteraseOpsonin ProteinsMolecular biologyCyclic Nucleotide Phosphodiesterases Type 4KineticsEndocrinologychemistry3'5'-Cyclic-AMP Phosphodiesterasesbiology.proteinHistaminemedicine.drugHistamineInflammation research : official journal of the European Histamine Research Society ... [et al.]
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Murine bone marrow-derived mast cells as potent producers of IL-9: costimulatory function of IL-10 and kit ligand in the presence of IL-1.

2000

Abstract Recently, the Th2-type cytokine IL-9 was identified by genetic mapping analyses as a key mediator that determines the susceptibility to asthma. This has been further supported by data from IL-9-transgenic mice in which the overexpression of IL-9 in the lung causes airway inflammation, mast cell hyperplasia, and bronchial hyperresponsiveness. In an accompanying paper, we demonstrate that murine bone marrow-derived mast cells (BMMC) after stimulation with either ionomycin, a combination of ionomycin and IL-1, or via IgE-Ag complexes and IL-1 are very potent producers of IL-9. Herein we show that a dramatic increase of IL-9 production is observed when BMMC activated with ionomycin/IL-…

medicine.medical_treatmentImmunologyEndogenyStem cell factorBone Marrow CellsBiologychemistry.chemical_compoundMiceAdjuvants ImmunologicmedicineImmunology and AllergyAnimalsMast CellsRNA MessengerReporter geneMice Inbred BALB CStem Cell FactorInterleukin-9TransfectionMolecular biologyInterleukin-10Interleukin 10medicine.anatomical_structureCytokinechemistryGene Expression RegulationIonomycinImmunologyBone marrow5' Untranslated RegionsInterleukin-1Journal of immunology (Baltimore, Md. : 1950)
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CCDC 240303: Experimental Crystal Structure Determination

2005

Related Article: E.Coronado, S.Curreli, C.Gimenez-Saiz, C.J.Gomez-Garcia|2012|Inorg.Chem.|51|1111|doi:10.1021/ic202269x

tetrakis(beta''-45:4'5'-bis(Ethylenedithio)-11'33'-tetrathiafulvalene) oxonium tris(oxalato-OO')-iron(iii) bromobenzene clathrateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 837033: Experimental Crystal Structure Determination

2012

Related Article: E.Coronado, S.Curreli, C.Gimenez-Saiz, C.J.Gomez-Garcia|2012|Inorg.Chem.|51|1111|doi:10.1021/ic202269x

tetrakis(beta''-45:4'5'-bis(Ethylenedithio)-11'33'-tetrathiafulvalene) oxonium tris(oxalato-OO')-iron(iii) bromobenzene clathrateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 837031: Experimental Crystal Structure Determination

2012

Related Article: E.Coronado, S.Curreli, C.Gimenez-Saiz, C.J.Gomez-Garcia|2012|Inorg.Chem.|51|1111|doi:10.1021/ic202269x

tetrakis(beta''-45:4'5'-bis(Ethylenedithio)-11'33'-tetrathiafulvalene) oxonium tris(oxalato-OO')-iron(iii) fluorobenzene clathrateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 749412: Experimental Crystal Structure Determination

2012

Related Article: E.Coronado, S.Curreli, C.Gimenez-Saiz, C.J.Gomez-Garcia|2012|Inorg.Chem.|51|1111|doi:10.1021/ic202269x

tetrakis(beta''-45:4'5'-bis(Ethylenedithio)-11'33'-tetrathiafulvalene) oxonium tris(oxalato-OO')-iron(iii) fluorobenzene clathrateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1523643: Experimental Crystal Structure Determination

2017

Related Article: Y.Y. Kim, J.M. Tanski|2017|Acta Crystallogr.,Sect.E:Cryst.Commun.|73|88|doi:10.1107/S2056989016020156

trichloro-(33'-di-t-butyl-55'66'-tetramethylbiphenyl-22'-diolato)-(tetrahydrofuran)-titanium(iv)Space GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 910884: Experimental Crystal Structure Determination

2014

Related Article: Màrius Tarrés, Clara Viñas, Ana M. Cioran, Mikko M. Hänninen, Reijo Sillanpää, Francesc Teixidor|2014|Chem.-Eur.J.|20|15808|doi:10.1002/chem.201403424

tris(mu-acetone)-bis(55'-4-(2-[2-(dioxidan-2-id-1-yl)ethoxy]ethoxy)butyl)-11'-commo-(1-ferro-23-dicarba-closo-dodecaborane(10))-(1'-ferro-2'3'-dicarba-closo-dodecaborane(10))-di-sodiumSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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