Search results for "57"
showing 10 items of 4186 documents
Differential memory persistence of odor mixture and components in newborn rabbits: competition between the whole and its parts
2014
Interacting with the mother during the daily nursing, newborn rabbits experience her body odour cues. In particular, the mammary pheromone (MP) contained in rabbit milk triggers the typical behaviour which helps to localize and seize the nipples. It also promotes the very rapid appetitive learning of simple or complex stimuli (odorants or mixtures) through associative conditioning. We previously showed that 24h after MP-induced conditioning to odorants A (ethyl isobutyrate) or B (ethyl maltol), newborn rabbits perceive the AB mixture in a weak configural way, i.e. they perceive the odour of the AB configuration in addition to the odours of the elements. Moreover, after conditioning to the m…
Smad7 controls resistance of colitogenic T cells to regulatory T cell-mediated suppression.
2008
Background & Aims Foxp3-expressing regulatory T cells (Tregs) play a key role in the maintenance of the gut immune homeostasis, and an intact transforming growth factor (TGF)-β signaling is required for their function. In inflammatory bowel disease (IBD), the TGF-β signaling is impaired because of high expression of the inhibitory molecule Smad7. Although no intrinsic defects in Tregs function have been shown in IBD, it is still unknown whether colitogenic T cells are susceptible to Treg-mediated suppression. In this study, we have investigated whether IBD mucosal CD4+ T cells are resistant to Tregs and whether Smad7 is involved in this process. Methods IBD lamina propria mononuclear cells …
Desarrollo de marcadores moleculares de aplicación en genómica y programas de mejora de cítricos
2002
Los cítricos son las especies frutales más importantes a escala mundial, siendo actualmente España el cuarto país productor. Esto contrasta con la escasez de estudios genéticos para su mejora, lo cual es debido a que presentan varios problemas, entre ellos su compleja biología reproductiva. Muchas especies de cítricos son apomícticas y sus semillas producen embriones nucelares que limitan el desarrollo de embriones zigóticos y por tanto, la construcción de familias segregantes. En los programas de mejora de cítricos y en los viveros es muy importante distinguir entre individuos zigóticos y nucelares para poder eliminar los genotipos no deseados. Normalmente, los isoenzimas se han empleado p…
El papel de la sociología en el ámbito del desarrollo local: aportaciones tras dos décadas de experiencia en la administración pública
2021
The Modified Heidelberg and the AI Appendicitis Score Are Superior to Current Scores in Predicting Appendicitis in Children: A Two-Center Cohort Study
2020
Background: Acute appendicitis represents the most frequent reason for abdominal surgery in children. Since diagnosis can be challenging various scoring systems have been published. The aim of this study was to evaluate and validate (and improve) different appendicitis scores in a very large cohort of children with abdominal pain. Methods: Retrospective analysis of all children that have been hospitalized due to suspected appendicitis at the Pediatric Surgery Department of the Altonaer Children's Hospital and University Medical Center Hamburg-Eppendorf from 01/2018 until 11/2019. Four different appendicitis scores (Heidelberg Appendicitis Score, Alvarado Score, Pediatric Appendicitis Score …
Toxicidad y acumulación de cadmio en poblaciones de diferentes especies de Artemia
2002
El presente trabajo se centra en el estudio comparativo de distintos aspectos de la respuesta frente a la exposición tóxica de cadmio de diferentes poblaciones de Artemia pertenecientes a las especies Artemia parthenogenetica, Artemia salina, Artemia franciscana y Artemia persimilis. La primera parte de este estudio, pone de manifiesto la variabilidad fenotípica de la respuesta letal a la exposición a cadmio que presentan los nauplios. En este sentido, la utilización de Modelos Lineales Generalizados ha sido de gran utilidad ya que ha permitido poner de manifiesto, a través de los parámetros que definen cada curva de mortalidad, diferencias en sensibilidad al tóxico y en la uniformidad de r…
L'assaig català en l'època postmoderna: funció social i especificitat estètica
2015
Aquesta tesi doctoral pretén oferir una definició completa i operativa de l'assaig entés com a gènere literari, seguint patrons estètics i sociològics. Aquesta definició s'aplica a un corpus d'anàlisi delimitat entre l'any 1962 i l'any 2012 i circumscrit al camp literari català, però aspira a ser homologable per a la resta de literatures europees. S'hi combinen, per tant, aportacions de la retòrica, la pragmàtica, l'anàlisi del discurs i la teoria de la literatura, les quals es concreten en l'estudi d'exemples del corpus establit.
Attentional Processes in Children With Attentional Problems or Reading Difficulties as Revealed Using Brain Event-Related Potentials and Their Source…
2020
Visual attention-related processes include three functional sub-processes: alerting, orienting, and inhibition. We examined these sub-processes using reaction times, event-related potentials (ERPs), and their neuronal source activations during the Attention Network Test (ANT) in control children, attentional problems (AP) children, and reading difficulties (RD) children. During the ANT, electroencephalography was measured using 128 electrodes on three groups of Finnish sixth-graders aged 12–13 years (control = 77; AP = 15; RD = 23). Participants were asked to detect the direction of a middle target fish within a group of five fish. The target stimulus was either preceded by a cue (center, d…
Event-Related Potentials to Changes in Sound Intensity Demonstrate Alterations in Brain Function Related to Depression and Aging
2020
Measures of the brain’s automatic electrophysiological responses to sounds represent a potential tool for identifying age- and depression-related neural markers. However, these markers have rarely been studied related to aging and depression within one study. Here, we investigated auditory event-related potentials (ERPs) in the brain that may show different alterations related to aging and depression. We used an oddball condition employing changes in sound intensity to investigate: (i) sound intensity dependence; (ii) sensory gating; and (iii) change detection, all within a single paradigm. The ERPs of younger (18–40 years) and older (62–80 years) depressed female participants and age-match…
Diagnostic Tools for Autism Spectrum Disorders by Gender: Analysis of Current Status and Future Lines
2021
Studies on the prevalence of autism spectrum disorders have shown gender disproportion. In recent years, there has been an increasing interest in this investigation area. There are two main research lines; the first is focused mostly on gender-related biological reasons that could account for low ASD prevalence in women (i.e., related to some protective factors related to hormones or the immune system, among others), and the second research line studies possible diagnostic biases. In the present study, a review of the latter line of research is made based on two main objectives: (a) analysis of possible biases in diagnostic tools and (b) other nonbiological ASD prevalence explained by gende…