Search results for "59"

Age- and quality-dependent DNA methylation correlate with melanin-based coloration in a wild bird

2018

Abstract Secondary sexual trait expression can be influenced by fixed individual factors (such as genetic quality) as well as by dynamic factors (such as age and environmentally induced gene expression) that may be associated with variation in condition or quality. In particular, melanin‐based traits are known to relate to condition and there is a well‐characterized genetic pathway underpinning their expression. However, the mechanisms linking variable trait expression to genetic quality remain unclear. One plausible mechanism is that genetic quality could influence trait expression via differential methylation and differential gene expression. We therefore conducted a pilot study examining…

Transferencia génica hepática hidrodinámica en modelos de cerdo in vivo y segmento humano ex vivo

2015

Introducción: La terapia génica es una estrategia terapéutica que pretende utilizar ácidos nucleicos como medicamentos para el tratamiento temporal o permanente de patologías hereditarias o adquiridas. En base al vehículo utilizado para entregar el gen, podemos clasificar la terapia génica en dos grupos: la terapia génica viral (vectores virales) y la terapia génica no viral (vectores no virales o ADN desnudo). La terapia no viral resulta menos eficiente pero más segura. La hidrofección (transferencia génica hidrodinámica) ha mostrado un gran potencial, con resultados terapéuticos en ratón. Sin embargo, cuando la hidrofección se ha trasladado a animales de mayor tamaño, el procedimiento ha …

Microformas: Mi solitario vuelo (Microrrelato), La mariposa efímera (Microcuento)

2021

The role of age and digital competence on the use of online health and social care services: A cross-sectional population-based survey

2022

Objective Online health and social care services are getting widespread which increases the risk that less advantaged groups may not be able to access these services resulting in digital exclusion. We examined the combined effects of age and digital competence on the use of online health and social care services. Methods We used a large representative population-based sample of 4495 respondents from Finland. Paper-based self-assessment questionnaire with an online response option was mailed to participants. The associations were analyzed using survey weighted logistic regression, exploring potential non-linear effects of age and controlling for potential sex differences. Results Higher age,…

Latvijas Vēstures Institūta Žurnāls. 2020, Nr. 2 (112)

2020

La aplicación del derecho extranjero en iberoamérica y la unión europea: : paralelismos desde la diferencia

2021

The potential application of a foreign law constitutes the logical outcome of any Private International Law? system. However, and despite its relevance, this issue lacks a common answer in the EU. In contrast to this, the analysis of the solutions drafted in Latin America as regards this issue grants a novel dimension to the European situation on this issue as well as highlights a meritorious reality that shows a high and very relevant degree of harmonization

El impacto del cambio climático en la movilidad humana : las migraciones climáticas en el contexto internacional y europeo

2021

For decades, the migration phenomenon has been one of the thorniest regulatory issues in the European Union (EU) policy. In addition, today, the fight against climate change in all regions of the world makes the situation worse for the new ?climate refugees? or ?environmental displaced people?, whose legal status is not yet covered by the ancient 1951 Refugee Convention.

ACTO II / ACT II Mujeres / Women ¿Es gay la música de Chopin? Aspectos de la recepción de la música de Chopin en el siglo XIX

2021

Considering that it is difficult, if not impossible, for an analysis of Chopin?s music to unmask some aspects of his private life (such as an alleged sexual and affective attraction for individuals of his own sex), we can however argue that, throughout the 19th century, a connection was established between his work and a ?feminine universe.? That connection might have had implications in the way in which the feminized image of its author was constructed. The analysis of certain aesthetic and stylistic traits of Chopin?s music can help understand the causes of that perception.

Joan B. Llinares, una reflexión filosófica a través de la literatura

2020

On Line Validation Exercise (OLIVE): A Web Based Service for the Validation of Medium Resolution Land Products. Application to FAPAR Products

2014

International audience; The OLIVE (On Line Interactive Validation Exercise) platform is dedicated to the validation of global biophysical products such as LAI (Leaf Area Index) and FAPAR (Fraction of Absorbed Photosynthetically Active Radiation). It was developed under the framework of the CEOS (Committee on Earth Observation Satellites) Land Product Validation (LPV) sub-group. OLIVE has three main objectives: (i) to provide a consistent and centralized information on the definition of the biophysical variables, as well as a description of the main available products and their performances (ii) to provide transparency and traceability by an online validation procedure compliant with the CEO…