Search results for "612"

The foreign language teaching profession in Finnish and Japanese society: a sociocultural comparison

2016

The social basis of a teaching profession is created through behavioural and cultural patterns, specific artefacts, and their connection to certain institutional practices. The purpose of this study is to discover the conditions that structure the teaching profession in a cultural context and to find out what it is to be a foreign language (FL) teacher in Finland and Japan. Both countries have high educational equality but with contrasting patterns of management policies that are manifested in their teacher education curricula. Educational policy documents as well as teacher interviews and classroom observations were conducted in both countries and the findings compared by one Japanese and …

Authenticity, normativity and social media

2015

Narrative Tools for Games : Focalization, Granularity, and the Mode of Narration in Games

2015

This article looks at three narratological concepts—focalization, granularity, and the mode of narration—and explores how these concepts apply to games. It is shown how these concepts can be used as tools for creating meaning-effects, which are understood here as cognitive responses from the player. Focalization is shown to have a hybrid form in games. This article also explores the different types of narrators and granularities in games, and how these three concepts can be used to create meaning-effects. This is done by discussing examples from several games, for example, Assassin’s Creed III, Skyrim, Fallout: New Vegas, and Civilization.

The International Comparable Corpus: Challenges in building multilingual spoken and written comparable corpora

2021

This paper reports on the efforts of twelve national teams in building the International Comparable Corpus (ICC; https://korpus.cz/icc) that will contain highly comparable datasets of spoken, written and electronic registers. The languages currently covered are Czech, Finnish, French, German, Irish, Italian, Norwegian, Polish, Slovak, Swedish and, more recently, Chinese, as well as English, which is considered to be the pivot language. The goal of the project is to provide much-needed data for contrastive corpus-based linguistics. The ICC corpus is committed to the idea of re-using existing multilingual resources as much as possible and the design is modelled, with various adjustments, on t…

Kieli- ja kielitaitokäsitykset tutkivan opettajan kenttäpäiväkirjamerkinnöissä

2018

This article focuses on a young teacher-researcher’s beliefs about language and language skills. The research is motivated by findings of former studies according with which teachers’ beliefs are often relatively permanent and have a strong effect on their teaching and evaluation practices. The data consists of a teacher-researcher’s diary notes from storytelling events (n=19) in which storycrafting has been used with young primary school pupils. The study was carried out by a theory-driven content analysis in order to reveal and to be able to assess teacher-researcher’s beliefs that are only implicitly present in the data: diary markings were analyzed by comparing them to widely used dicho…

The Representation of Mikhail Gorbachev in the Twenty-first Century Russian Media

2013

The aim of this study is to investigate the representation of Mikhail Gorbachev in contemporary Russian media discourse. Attention is paid to Gorbachev's social roles and activities as well as his personality, as presented in Russian news texts. The empirical data were collected over the period from 2000 to 2009 from seven major Russian newspapers. According to these data, a dual relationship to Gorbachev exists: in the West he is an honoured politician with a high profile, whereas in Russia the attitude towards him is ambivalent. In most texts he is represented as a once important political actor.

Combined Bacteriophage and Antibiotic Treatment Prevents Pseudomonas aeruginosa Infection of Wild Type and cftr- Epithelial Cells

2020

International audience; With the increase of infections due to multidrug resistant bacterial pathogens and the shortage of antimicrobial molecules with novel targets, interest in bacteriophages as a therapeutic option has regained much attraction. Before the launch of future clinical trials, in vitro studies are required to better evaluate the efficacies and potential pitfalls of such therapies. Here we studied in an ex vivo human airway epithelial cell line model the efficacy of phage and ciprofloxacin alone and in combination to treat infection by Pseudomonas aeruginosa. The Calu-3 cell line and the isogenic CFTR knock down cell line (cftr-) infected apically with P. aeruginosa strain PAO…

Efecto del ejercicio físico agotador sobre el estrés oxidativo asociado al envejecimiento

2003

La teoría del envejecimiento más aceptada y testada es la teoría de los radicales libres en el envejecimiento, la cual afirma que el envejecimiento y la muerte se producen por un aumento acumulativo de los efectos de los radicales libres a lo largo de la vida. Por otro lado, los radicales libres están implicados en el ejercicio físico, aumentando éstos cuando se produce un ejercicio físico agotador, provocando estrés oxidativo. Con el objetivo de estudiar el papel de la xantina óxidoreductasa como fuente de radicales libres en el proceso de envejecimiento y su contribución al estrés oxidativo en el ejercicio físico agotador, se ha estudiado el efecto del ejercicio físico agotador en ratas w…

The importance of the nuclear glutathione in the cell proliferation

2009

The present thesis offers an insight in the importance of nuclear GSH in cell proliferation. The research was performed in three different cellular models of diverse proliferating activity: immortalized mouse embryonic fibroblasts 3T3, mammary adenocarcinoma cell line MCF7 and primary embryonic neuralonal culture. The results presented here provide evidence that suggest that the relationship between GSH level and telomerase activity, previously described by our group for 3T3 fibroblasts is a common phenomenon in mammalian cells. Reduced glutathione emerged as a driving force of cell cycle progression; high level of GSH coincided with the peak of telomerase activity and preceded the exponent…

Fenómenos mitocondriales y nucleares relacionados con la resistencia a la apoptosis. Importancia del estrés oxidativo

2009

En el presente trabajo se ha estudiado la relación entre el núcleo y la mitocondria y la importancia de la compartimentación del GSH durante la resistencia a la apoptosis inducida por el tratamiento con cisplatino. Así mismo, se ha evaluado la implicancia de la proteína bcl-2 en la compartimentación del GSH como mecanismo de resistencia a la muerte por apoptosis. Para ello se ha utilizado la cepa celular MCF7 wild type y un homólogo que sobre-expresa la proteína bcl-2.Los resultados muestran que el tratamiento con cisplatino detiene las células en la fase de proliferación, lo que provocaría la detención del ciclo celular y la muerte celular por apoptosis. La proliferación celular se desarro…