Search results for "61"

showing 10 items of 3634 documents

A functional variant of the serotonin transporter gene (SLC6A4) moderates impulsive choice in attention-deficit/hyperactivity disorder boys and sibli…

2011

Item does not contain fulltext BACKGROUND: Impulsive drive for immediate reward (IDIR) and delay aversion are dissociable elements of the preference for immediate over delayed rewards seen in attention-deficit/hyperactivity disorder (ADHD). We hypothesized that IDIR would be associated with dopamine regulating genes and delay aversion would be associated with serotonin-regulating genes. METHODS: Impulsive drive for immediate reward and delay aversion were measured in 459 male children and adolescents (328 ADHD and 131 unaffected siblings) with a laboratory choice task. The sample was genotyped for the 5HTT (SLC6A4) promoter serotonin-transporter-linked polymorphic region polymorphism and a …

DEFICIT HYPERACTIVITY DISORDERMedizinSocial Sciencesimpulsivity610 Medicine & healthCHILDRENSingle-nucleotide polymorphismGenomic disorders and inherited multi-system disorders Functional Neurogenomics [IGMD 3]attention-deficit/hyperactivity disorderImpulsivityCOMBINED-TYPE ADHDREACTION-TIME PERFORMANCEDevelopmental psychologyGenomic disorders and inherited multi-system disorders [IGMD 3]DOPAMINE03 medical and health sciences0302 clinical medicineDopaminemedicineAttention deficit hyperactivity disorderddc:610Medizinische Fakultät » Universitätsklinikum Essen » LVR-Klinikum Essen » Klinik für Psychiatrie Psychosomatik und Psychotherapie des Kindes- und JugendaltersAlleleBiological PsychiatrySerotonin transporter030304 developmental biologyDopamine transporterGeneticsMental Health [NCEBP 9]0303 health sciencesDELAY AVERSIONbiologyTRYPTOPHAN DEPLETIONASSOCIATION10058 Department of Child and Adolescent Psychiatrymedicine.diseasePOLYMORPHISM5-HTTLPR (SLC6A4)5-HTTLPRbiology.proteinCRITERION VALIDITYmedicine.symptomDAT1 (SLC6A3)Psychology2803 Biological PsychiatryFunctional Neurogenomics [DCN 2]030217 neurology & neurosurgerymedicine.drugBiological Psychiatry
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Mutations in CTC1, encoding conserved telomere maintenance component 1, cause Coats plus

2012

Coats plus is a highly pleiotropic disorder particularly affecting the eye, brain, bone and gastrointestinal tract. Here, we show that Coats plus results from mutations in CTC1, encoding conserved telomere maintenance component 1, a member of the mammalian homolog of the yeast heterotrimeric CST telomeric capping complex. Consistent with the observation of shortened telomeres in an Arabidopsis CTC1 mutant and the phenotypic overlap of Coats plus with the telomeric maintenance disorders comprising dyskeratosis congenita, we observed shortened telomeres in three individuals with Coats plus and an increase in spontaneous γ 3H2AX-positive cells in cell lines derived from two affected individual…

DNA polymeraseMolecular Sequence DataTelomere-Binding ProteinsHistones/metabolismHDE GENHDE NEU PEDCST complexCEREBRORETINAL MICROANGIOPATHY FAMILIAL SYNDROME CALCIFICATIONS CYSTS PROTEIN DNA LEUKOENCEPHALOPATHY EVOLUTION DEFECTSHistoneschemistry.chemical_compoundAbnormalities Multiple/geneticsGeneticsmedicineAbnormalities MultipleGenetic Predisposition to DiseaseGeneticsTelomere-binding proteinTelomere/pathologyddc:618biologyBase SequenceGenetic Predisposition to Disease/geneticsDNA replicationSequence Analysis DNATelomeremedicine.diseaseFlow CytometryTelomereCell biologyRetinal Telangiectasis/genetics/pathologychemistrySequence Analysis DNA/methodsbiology.proteinRetinal TelangiectasisPrimaseTelomere-Binding Proteins/geneticsDNADyskeratosis congenitaNature Genetics
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"Table 12" of "Measurement of $Z / \gamma^\ast +jet+X$ angular distributions in $p \bar{p}$ collisions at $\sqrt{s}=1.96$ TeV"

2009

Individual percentage contributions to the systematic error for the binning in ABS(YRAP(P=3)+YRAP(P=4))/2 for Z/GAMMA* transverse momentum > 45 GeV.

DSIG/DABS(YRAP(PInclusiveSingle Differential Cross Section20477612047761Z ProductionPBAR P --> Z0 JET XJet ProductionPBAR P --> GAMMA* JET X1960.0
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"Table 104" of "Studies of QCD at e+ e- centre-of-mass energies between 91-GeV and 209-GeV."

2004

Thrust Minor distribution at c.m. energy 161.00 GeV.

DSIG/DMINORSingle Differential Cross SectionAstrophysics::High Energy Astrophysical PhenomenaE+ E- --> HADRONSE+ E- ScatteringPhysics::Space PhysicsExclusiveHigh Energy Physics::ExperimentNuclear Experiment161.0
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"Table 14" of "Measurement of the inclusive jet cross-section in p anti-p collisions at s**(1/2) =1.96-TeV"

1970

Detailed systematic errors for the absolute value of the jet rapidity in the range 0.4 to 0.8: (1st) Luminosity (2nd) eta-intercalibration (3rd) eta-intercalibration (4th) eta-intercalibration (5th) JES resolution bias (6th) Resolution method.

DSYSInclusive20477612047761PBAR P --> JET XHigh Energy Physics::ExperimentAstrophysics::Cosmology and Extragalactic AstrophysicsJet ProductionNuclear Experiment
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"Table 9" of "Measurement of the inclusive jet cross-section in p anti-p collisions at s**(1/2) =1.96-TeV"

1970

Detailed systematic errors for the absolute value of the jet rapidity in the range 0.0 to 0.4: (1st) Luminosity (2nd) eta-intercalibration (3rd) eta-intercalibration (4th) eta-intercalibration (5th) JES resolution bias (6th) Resolution method.

DSYSInclusive20477612047761PBAR P --> JET XHigh Energy Physics::ExperimentAstrophysics::Cosmology and Extragalactic AstrophysicsJet ProductionNuclear ExperimentAstrophysics::Galaxy Astrophysics
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"Table 33" of "Measurement of the inclusive jet cross-section in p anti-p collisions at s**(1/2) =1.96-TeV"

1970

Detailed systematic errors for the absolute value of the jet rapidity in the range 2.0 to 2.4: (1st) Uncorrelated uncertainty (2nd) EM energy scale (3rd) Photon energy scale (4th) High p_{T} extrapolation (5th) eta-intercalibration (6th) Detector showering.

DSYSInclusive20477612047761PBAR P --> JET XHigh Energy Physics::ExperimentJet Production
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"Table 13" of "Measurement of the inclusive jet cross-section in p anti-p collisions at s**(1/2) =1.96-TeV"

1970

Detailed systematic errors for the absolute value of the jet rapidity in the range 0.4 to 0.8: (1st) Uncorrelated uncertainty (2nd) EM energy scale (3rd) Photon energy scale (4th) High p_{T} extrapolation (5th) eta-intercalibration (6th) Detector showering.

DSYSInclusive20477612047761PBAR P --> JET XHigh Energy Physics::ExperimentJet Production
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"Table 23" of "Measurement of the inclusive jet cross-section in p anti-p collisions at s**(1/2) =1.96-TeV"

1970

Detailed systematic errors for the absolute value of the jet rapidity in the range 1.2 to 1.6: (1st) Uncorrelated uncertainty (2nd) EM energy scale (3rd) Photon energy scale (4th) High p_{T} extrapolation (5th) eta-intercalibration (6th) Detector showering.

DSYSInclusive20477612047761PBAR P --> JET XHigh Energy Physics::ExperimentJet Production
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"Table 28" of "Measurement of the inclusive jet cross-section in p anti-p collisions at s**(1/2) =1.96-TeV"

1970

Detailed systematic errors for the absolute value of the jet rapidity in the range 1.6 to 2.0: (1st) Uncorrelated uncertainty (2nd) EM energy scale (3rd) Photon energy scale (4th) High p_{T} extrapolation (5th) eta-intercalibration (6th) Detector showering.

DSYSInclusive20477612047761PBAR P --> JET XHigh Energy Physics::ExperimentJet Production
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