Search results for "65"

Auszüge aus Einer alten geschriebenen Liefländ

1771

Auszüge aus Einer alten geschriebenen Liefländ : CHRONICA von Jürgen Helms welche der Landrichter des Rigisch. Kreyßes H. v. Aderkas. besitzet u. die den Titel führt Warhafftige auß Copiae derre Lyfflandische Vndt Churlandische Chronnica Vndt Etzliche Geschichte so sich alhie begeben vndt zu getragenn haben Vohrnemblich zu Riga 1.) Von Erfindung, Erbavwung, Fruchtbarkeit, vnd dero ersten Regierung oderRegenten deß Landeß ist biß auff die Schwertbrüder 2) Vonn Ersten Herre Meister Teutsches Ordens, biß auff den Letzten pp 3.) Von dem Ersten Königen vnd Fürsten in Lyfflant vnd Churlant pp J.C.B. [2], 150, [8] S; Ill. [164 Federzeichn., grau laviert, Tusche]; [1] Bl.Karte. 31,4 x 20 cm. Handsc…

Marx en la Sociología

2018

Nuevas aportaciones al corpus pictórico valenciano del primer renacimiento: Rodrigo de Osona, Maestro de Perea, y Pere Cabanes I

2016

Artificial Chromosomes to Explore and to Exploit Biosynthetic Capabilities of Actinomycetes

2012

Actinomycetes are an important source of biologically active compounds, like antibiotics, antitumor agents, and immunosuppressors. Genome sequencing is revealing that this class of microorganisms has larger genomes relative to other bacteria and uses a considerable fraction of its coding capacity (5–10%) for the production of mostly cryptic secondary metabolites. To access actinomycetes biosynthetic capabilities or to improve the pharmacokinetic properties and production yields of these chemically complex compounds, genetic manipulation of the producer strains can be performed. Heterologous expression in amenable hosts can be useful to exploit and to explore the genetic potential of actinom…

Broadband spectral analysis of MXB 1659-298 in its soft and hard state

2019

The X-ray transient eclipsing source MXB 1659-298 went in outburst in 1999 and 2015, respectively, during which it was observed by XMM-Newton, NuSTAR and Swift. Using these observations we studied the broadband spectrum of the source to constrain the continuum components and to verify the presence of a reflection component. We analysed the soft and hard state of the source, finding that the soft state can be modelled with a thermal component associated with the inner accretion disc plus a Comptonised component. A smeared reflection component and the presence of an ionised absorber are also requested in the best-fit model. On the other hand, the direct continuum emission in the hard state ca…

NuSTARandXMM–Newtonbroad-band spectrum of SAX J1808.4–3658 during its latest outburst in 2015

2018

The first discovered accreting millisecond pulsar, SAX J1808.4-3658, went into X-ray outburst in April 2015. We triggered a 100 ks XMM-Newton ToO, taken at the peak of the outburst, and a 55 ks NuSTAR ToO, performed four days apart. We report here the results of a detailed spectral analysis of both the XMM-Newton and NuSTAR spectra. While the XMM-Newton spectrum appears much softer than in previous observations, the NuSTAR spectrum confirms the results obtained with XMM-Newton during the 2008 outburst. We find clear evidence of a broad iron line that we interpret as produced by reflection from the inner accretion disk. For the first time, we use a self-consistent reflection model to fit the…

The damped harmonic oscillator in deformation quantization

2005

We propose a new approach to the quantization of the damped harmonic oscillator in the framework of deformation quantization. The quantization is performed in the Schr\"{o}dinger picture by a star-product induced by a modified "Poisson bracket". We determine the eigenstates in the damped regime and compute the transition probability between states of the undamped harmonic oscillator after the system was submitted to dissipation.

Shear design of high strength concrete beams in MRFs

2019

This paper presents the criteria for the shear design of high strength concrete (HSC) beams in moment resisting frames (MRFs). The formulation of an analytical model is provided for the case of beams with longitudinal reinforcement in the presence of transverse stirrups. The model is of additive type, in the meaning that the shear resistance of the beam is evaluated as the sum of several contributions. In particular, the contribution of concrete, longitudinal rebars, and transversal reinforcement are taken into account. Furthermore, for assessing the concrete contribution, a classical approach is followed, according to which two effects arise in the shear mechanism: the arc and the beam eff…

Injectable Hydrogel for Synergetic Low Dose Radiotherapy, Chemodynamic Therapy and Photothermal Therapy

2021

Higher doses of radiotherapy (RT) are associated with resistance induction, therefore highly selective and controllable radiosensitizers are urgently needed. To address this issue, we developed a FeGA-based injectable hydrogel system (FH) that can be used in combination with low-dose radiation. Our FH can deliver FeGA directly to the tumor site via intratumoral injection, where it is a reservoir-based system to conserve FeGA. The photothermal properties of FeGA steadily dissolve FH under laser irradiation, and, simultaneously, FeGA reacts with a large amount of H2O2 in the cell to produce OH (Fenton reaction) which is highly toxic to mitochondria, rendering the cell inactive and reducing ra…

Smart materials meet multifunctional biomedical devices:Current and prospective implications for nanomedicine

2017

With the increasing advances in the fabrication and in monitoring approaches of nanotechnology devices, novel materials are being synthesized and tested for the interaction with biological environments. Among them, smart materials in particular provide versatile and dynamically tunable platforms for the investigation and manipulation of several biological activities with very low invasiveness in hardly accessible anatomical districts. In the following, we will briefly recall recent examples of nanotechnology-based materials that can be remotely activated and controlled through different sources of energy, such as electromagnetic fields or ultrasounds, for their relevance to both basic scien…