Search results for "69"
showing 10 items of 1106 documents
Prevention of chemotherapy‐induced cachexia by ACVR2B ligand blocking has different effects on heart and skeletal muscle
2017
Background Toxicity of chemotherapy on skeletal muscles and the heart may significantly contribute to cancer cachexia, mortality, and decreased quality of life. Doxorubicin (DOX) is an effective cytostatic agent, which unfortunately has toxic effects on many healthy tissues. Blocking of activin receptor type IIB (ACVR2B) ligands is an often used strategy to prevent skeletal muscle loss, but its effects on the heart are relatively unknown. Methods The effects of DOX treatment with or without pre-treatment with soluble ACVR2B-Fc (sACVR2B-Fc) were investigated. The mice were randomly assigned into one of the three groups: (1) vehicle (PBS)-treated controls, (2) DOX-treated mice (DOX), and (3) …
De rebus, Emmanuelis Regis Lusitaniae invictissimi virtute et auspicio gestis libri duodecim
Sig. A-Gg8, Hh1 Escut heràldic de "Henricus Cardinalis, infans Portugalliae" a la port. - Capitals grav Reclams
Supuestos metodológicos y epistemológicos del análisis de género en cinco estudios de casos latinoamericanos
2019
Evolucion paleoambiental desde el Holoceno temprano hasta la actualidad del marjal de Almenara (Mediterráneo occidental)
2018
The main aim of this study is to characterize the different stages in the palaeoenvironmental evolution of the Almenara marsh, Spain, from the early Holocene to the present day. This marsh is one of the most important in Castellón province. Five cores extracted from the marsh underwent sedimentological analysis, micropalaeontological study (foraminifera, ostracods and gastropods) and 14C dating. The results show that before the maximum transgression of the Mediterranean during the Marine Isotope Stage 1 (5500 cal yr. BP dating in the Almenara marsh), the area was occupied by a brackish marsh (prior to the 8.2 ka event). During the middle Holocene, the regional sea level rise and later stabi…
Lamentables suspiros del Real Convento de Predicadores de Valencia por la muerte de su sapientissimo hijo ... Fr. Marcelo Marona ... Obispo que fué …
1695
Port. amb orla tip. Caplletres ornades, bandes El f. de grav. calc., retrat de Fr. Marcelo Marona Sign. : œ-œœ4, A-F4, G2 Text amb postil·les marginals Reclams
Los dibujos de la Escuela de Agrimensura de Valencia. 1864 ? 1885. Análisis gráfico
2018
Los corregidores de Betanzos en la segunda mitad del siglo XVIII (1748-1808): análisis social y profesional
2020
El objetivo de este trabajo consiste en estudiar la vertiente social del poder, analizando para ello la trayectoria de quienes ocuparon el corregimiento de Betanzos desde su creación, a mediados del siglo XVIII, hasta que el estallido de la guerra de la Independencia, en 1808, empezó a alterar la, hasta ese momento, estable división administrativa del reino. Origen geográfico, estudios cursados, vínculos familiares o trayectoria profesional serán algunos de los aspectos a analizar, como también la actuación desarrollada por quienes ostentaron la titularidad del corregimiento. The objective of this work is to study the social side of power, analyzing for it the trajectory of those who occupi…
El Círculo de Bellas Artes de Valencia y el estudio conservativo de su colección
2015
Investigation of absorber and heterojunction in the pure sulphide kesterite
2021
This paper aims to study the properties of the absorber layer and the heterojunction in kesterite solar cells. The Cu2ZnSnS4 (CZTS) thin films were layered on a glass substrate from a colloidal solution of metal salts and thiourea dissolved in a mixture of water and ethanol and deposited by spin coating technique. The samples were then heat treated in a furnace, in the presence of sulphur powder and under a nitrogen gas flow. The results revealed the formation of homogeneous layers of a pure kesterite phase of CZTS crystallites after heat treatment with correct stoichiometry and oxidation states. The optical transmission measurements indicate an energy band-gap of 1.4 eV and an absorption c…
Mechanical behavior of a sandwich with corrugated GRP core: numerical modeling and experimental validation
2014
In this work the mechanical behaviour of a core reinforced composite sandwich structure is studied. The sandwich employs a Glass Reinforced Polymer (GRP) orthotropic material for both the two external skins and the inner core web. In particular, the core is designed in order to cooperate with the GRP skins in membrane and flexural properties by means of the addition of a corrugated laminate into the foam core. An analytical model has been developed to replace a unit cell of this structure with an orthotropic equivalent thick plate that reproduces the in plane and out of plane behaviour of the original geometry. Different validation procedures have been implemented to verify the quality of t…