Search results for "6R"
showing 10 items of 23 documents
Varieties of algebras with pseudoinvolution and polynomial growth
2017
Let A be an associative algebra with pseudoinvolution (Formula presented.) over an algebraically closed field of characteristic zero and let (Formula presented.) be its sequence of (Formula presented.) -codimensions. We shall prove that such a sequence is polynomially bounded if and only if the variety generated by A does not contain five explicitly described algebras with pseudoinvolution. As a consequence, we shall classify the varieties of algebras with pseudoinvolution of almost polynomial growth, i.e. varieties of exponential growth such that any proper subvariety has polynomial growth and, along the way, we shall give also the classification of their subvarieties. Finally, we shall de…
Benchmarking the sustainable manufacturing paradigm via automatic analysis and clustering of scientific literature: A perspective from Italian techno…
2019
Abstract The number of scientific papers in the field of Sustainable Manufacturing (SM) shows a strong growth of interest in this topic in the last 20 years. Despite this huge number of publications, a clear statement of the profound meaning of Sustainable Manufacturing, or at least a strong theoretical support, is still missing. The 6R framework seems to be a first attempt to rationalize this issue, as it is an axiomatic identification of its true nature. Recognizing the pursuing of one or more of the Reduce-Recycle-Reuse-Recover-Redesign-Remanufacture principles allows users to identify if any manufacturing action is in the right direction of sustainability. In the paper, the authors spec…
Coexpression of IL-6 and soluble IL-6R causes nodular regenerative hyperplasia and adenomas of the liver
1998
Studies with tumor necrosis factor p55 receptor- and interleukin-6 (IL-6)-deficient mice have shown that IL-6 is required for hepatocyte proliferation and reconstitution of the liver mass after partial hepatectomy. The biological activities of IL-6 are potentiated when this cytokine binds soluble forms of its specific receptor subunit (sIL-6R) and the resulting complex interacts with the transmembrane signaling chain gp130. We show here that double transgenic mice expressing high levels of both human IL-6 and sIL-6R under the control of liver-specific promoters spontaneously develop nodules of hepatocellular hyperplasia around periportal spaces and present signs of sustained hepatocyte prol…
The neuropeptide 26RFa (QRFP) is a key regulator of glucose homeostasis and its activity is markedly altered in obese/hyperglycemic mice
2019
International audience; Recent studies have shown that the hypothalamic neuropeptide 26RFa regulates glucose homeostasis by acting as an incretin, and increasing insulin sensitivity. In this study, we further characterized the role of the 26RFa/GPR103 peptidergic system in the global regulation of glucose homeostasis using a 26RFa receptor antagonist, and also assessed whether a dysfunction of the 26RFa/GPR103 system occurs in obese hyperglycemic mice. Firstly, we demonstrate that administration of the GPR103 antagonist reduces the global glucose-induced incretin effect and insulin sensitivity whereas, conversely, administration of exogenous 26RFa attenuates glucose-induced hyperglycemia. U…
Computing with Rational Symmetric Functions and Applications to Invariant Theory and PI-algebras
2012
The research of the first named author was partially supported by INdAM. The research of the second, third, and fourth named authors was partially supported by Grant for Bilateral Scientific Cooperation between Bulgaria and Ukraine. The research of the fifth named author was partially supported by NSF Grant DMS-1016086.
New rotational levels in $^{186}$Re nucleus
2020
International audience; Excited levels of 186 Re have been studied using results of the single γ -ray spectra measurements following the thermal neutron capture reaction. Energies and intensities of more than 500 γ -transitions have been obtained with the high-resolution crystal diffraction spectrometer GAMS5 of ILL. Most of the obtained intense γ -transitions have been placed in the 186 Re level scheme. A number of new levels, as well as the depopulation for levels observed earlier in the 187 Re (p,d)186 Re reaction measurements have been proposed. Structure of 186 Re levels is interpreted in terms of two-quasiparticle plus rotor coupling model and compared with that of the neighbouring do…
Multialternating graded polynomials and growth of polynomial identities
2012
Let G be a finite group and A a finite dimensional G-graded algebra over a field of characteristic zero. When A is simple as a G-graded algebra, by mean of Regev central polynomials we construct multialternating graded polynomials of arbitrarily large degree non vanishing on A. As a consequence we compute the exponential rate of growth of the sequence of graded codimensions of an arbitrary G-graded algebra satisfying an ordinary polynomial identity. In particular we show it is an integer. The result was proviously known in case G is abelian.
Some characterizations of algebras with involution with polynomial growth of their codimensions
2018
Let A be an associative algebra endowed with an involution ∗ of the first kind and let c ∗n (A) denote the sequence of ∗-codimensions of A. In this paper, we are interested in algebras with involution such that the ∗-codimension sequence is polynomially bounded. We shall prove that A is of this kind if and only if it satisfies the same identities of a finite direct sum of finite dimensional algebras with involution A i , each of which with Jacobson radical of codimension less than or equal to one in A i . We shall also relate the condition of having polynomial codimension growth with the sequence of cocharacters and with the sequence of colengths. Along the way, we shall show that the multi…
Decoding the Mechanism of Action of Rapid-Acting Antidepressant Treatment Strategies: Does Gender Matter?
2019
Gender differences play a pivotal role in the pathophysiology and treatment of major depressive disorder. This is strongly supported by a mean 2:1 female-male ratio of depression consistently observed throughout studies in developed nations. Considering the urgent need to tailor individualized treatment strategies to fight depression more efficiently, a more precise understanding of gender-specific aspects in the pathophysiology and treatment of depressive disorders is fundamental. However, current treatment guidelines almost entirely neglect gender as a potentially relevant factor. Similarly, the vast majority of animal experiments analysing antidepressant treatment in rodent models exclus…
Interleukin-36α axis is modulated in patients with primary Sjögren's syndrome.
2015
Summary The aim of this study was to investigate the expression of the interleukin (IL)-36 axis in patients with primary Sjögren's syndrome (pSS). Blood and minor labial salivary glands (MSG) biopsies were obtained from 35 pSS and 20 non-Sjögren's syndrome patients (nSS) patients. Serum IL-36α was assayed by enzyme-linked immunosorbent assay (ELISA). IL-36α, IL-36R, IL-36RA, IL-38, IL-22, IL-17, IL-23p19 and expression in MSGs was assessed by reverse transcription–polymerase chain reaction (RT–PCR), and tissue IL-36α and IL-38 expression was also investigated by immunohistochemistry (IHC). αβ and γδ T cells and CD68+ cells isolated from MSGs were also studied by flow cytometry and confocal …