Search results for "72"

Oncolytic parvovirus H1 induces release of heat-shock protein HSP72 in susceptible human tumor cells but may not affect primary immune cells.

2003

Certain autonomous parvoviruses preferentially replicate in and kill in vitro-transformed cells and may reduce the incidence of spontaneous and implanted tumors in animals. Hence, these viruses and their derivatives are currently under evaluation as antitumor vectors. However, the mechanisms underlying their tumor-suppressing properties are not yet understood. We asked whether the lytic parvovirus H1 may enhance the immunogenicity of infected tumor cells. Out of human melanoma and gastrointestinal tumor cells, we selected the cell line SK29-Mel-1 being very susceptible to H1-induced apoptotic killing. Here, no upregulation of HLA class I and costimulatory molecules could be observed followi…

Genomic portrait of a sporadic amyotrophic lateral sclerosis case in a large spinocerebellar ataxia type 1 family

2020

Background: Repeat expansions in the spinocerebellar ataxia type 1 (SCA1) gene ATXN1 increases the risk for amyotrophic lateral sclerosis (ALS), supporting a relationship between these disorders. We recently reported the co-existence, in a large SCA1 family, of a clinically definite ALS individual bearing an intermediate ATXN1 expansion and SCA1 patients with a full expansion, some of which manifested signs of lower motor neuron involvement. Methods: In this study, we employed a systems biology approach that integrated multiple genomic analyses of the ALS patient and some SCA1 family members. Results: Our analysis identified common and distinctive candidate genes/variants and related biolog…

Hyperspectral UAV-Imagery and photogrammetric canopy height model in estimating forest stand variables

2017

Remote sensing using unmanned aerial vehicle (UAV) -borne sensors is currently a highly interesting approach for the estimation of forest characteristics. 3D remote sensing data from airborne laser scanning or digital stereo photogrammetry enable highly accurate estimation of forest variables related to the volume of growing stock and dimension of the trees, whereas recognition of tree species dominance and proportion of different tree species has been a major complication in remote sensing-based estimation of stand variables. In this study the use of UAV-borne hyperspectral imagery was examined in combination with a high-resolution photogrammetric canopy height model in estimating forest v…

Unmanned aerial system imagery and photogrammetric canopy height data in area-based estimation of forest variables

2015

In this paper we examine the feasibility of data from unmanned aerial vehicle (UAV)-borne aerial imagery in stand-level forest inventory. As airborne sensor platforms, UAVs offer advantages cost and flexibility over traditional manned aircraft in forest remote sensing applications in small areas, but they lack range and endurance in larger areas. On the other hand, advances in the processing of digital stereo photography make it possible to produce three-dimensional (3D) forest canopy data on the basis of images acquired using simple lightweight digital camera sensors. In this study, an aerial image orthomosaic and 3D photogrammetric canopy height data were derived from the images acquired …

Productive and vegetative behaviour of olive cultivars in super high-density olive grove

2015

In recent years, there has been an increase in interest in super high-density (SHD) olive (Olea europaea L.) groves because they offer early entry into production, increased productivity and the possibility of using modified mechanical vine harvesters. This study was carried out in a young SHD olive grove to examine vegetative, histo-anatomical and productive characteristics and oil quality of the Spanish Arbequina and Italian Maurino and Leccino cultivars, characterized by low, low-to-medium and high vigor, respectively. Arbequina had low vigor and limited development in height and width, as well as a high leaf/wood ratio. Maurino had a canopy volume similar to that of Arbequina and, despi…

Tracing the fate of microplastic carbon in the aquatic food web by compound-specific isotope analysis

2019

Increasing abundance of microplastics (MP) in marine and freshwaters is currently one of the greatest environmental concerns. Since plastics are fairly resistant to chemical decomposition, breakdown and reutilization of MP carbon complexes requires microbial activity. Currently, only a few microbial isolates have been shown to degrade MPs, and direct measurements of the fate of the MP carbon are still lacking. We used compound-specific isotope analysis to track the fate of fully labelled 13C-polyethylene (PE) MP carbon across the aquatic microbial-animal interface. Isotopic values of respired CO2 and membrane lipids showed that MP carbon was partly mineralized and partly used for cell growt…

Toxicity of waste gasification bottom ash leachate

2011

Abstract Toxicity of waste gasification bottom ash leachate from landfill lysimeters (112 m3) was studied over three years. The leachate of grate incineration bottom ash from a parallel setup was used as reference material. Three aquatic organisms (bioluminescent bacteria, green algae and water flea) were used to study acute toxicity. In addition, an ethoxyresorufin-O-deethylase (EROD) assay was performed with mouse hepatoma cells to indicate the presence of organic contaminants. Concentrations of 14 elements and 15 PAH compounds were determined to characterise leachate. Gasification ash leachate had a high pH (9.2–12.4) and assays with and without pH adjustment to neutral were used. Gasifi…

Relacion de las festivas aclamaciones, con que celebró ... Valencia la noticia de los ... Desposorios de ... Don Carlos Sebastian de Borbon y Farnese…

Sign. A-E4 Precedeix al tít.: Creu grega Capital grav Sign. A-E4. - Sense port. - Reclams

Carta pastoral que el ... Cardenal Belluga, Obispo de Cartagena ... escrive desde la Corte de Roma para el Cabildo de su Santa iglesia Cathedral ... …

1724

Sig. [A]-C4, D2 Port. orlada, amb banda. - Text amb notes merginals. - Capital grav.

Carta pastoral que el ... Cardenal Belluga, Obispo de Cartagena ... escrive desde la Corte de Roma para el Cabildo de su Santa iglesia Cathedral ... …

Sig. [A]-C4, D2 Signat al final "Luis Cardenal Belluga" Port. orlada, amb banda. - Text amb notes merginals. - Capital grav