Search results for "72"

Signal transduction pathways of membrane expression of proteinase 3 (PR‐3) in human endothelial cells

1997

At present, the exact mechanism of the pathogenic effect of anti-PR-3 antibodies remains unknown. Interaction of anti-neutrophil cytoplasmic antibodies (ANCAs) with human umbilical vein endothelial cells (HUVECs) may play a key role. Recently we were able to show that ANCAs recognize their target antigen, PR-3, translocated into the membrane of HUVECs. The objective of this study was to investigate regulation, i.e. signal transduction pathways, of PR-3 expression in endothelial cells. HUVECs were isolated according to the method of Jaffe et al. and cultured under standard conditions. A cyto-enzyme-linked immunosorbent assay (ELISA) with unfixed cells was performed. Membrane-expressed PR-3 w…

Multifunctionality: Epistemic diversity and concept oriented research clusters

2008

International audience; This paper provides a mapping of the different uses of the word multifunctionality. To explore the diversity of meanings and interpretations, a comparative analysis was conducted through five national case studies in France, the Netherlands, Poland, Spain and Switzerland. The analysis conducted at national level makes it possible to identify eight Concept Oriented Research Clusters (CORCs), based on a relative homogeneity in the research practices, in the research questions addressed, in the concepts used or discussed by scientists to lead their work and in the scientific disciplines, the stream of thought or possibly the epistemic community researchers belong to. Th…

Nitrous oxide emission budgets and land-use-driven hotspots for organic soils in Europe

2014

Organic soils are a main source of direct emissions of nitrous oxide (N2O), an important greenhouse gas (GHG). Observed N2O emissions from organic soils are highly variable in space and time, which causes high uncertainties in national emission inventories. Those uncertainties could be reduced when relating the upscaling process to a priori-identified key drivers by using available N2O observations from plot scale in empirical approaches. We used the empirical fuzzy modelling approach MODE to identify main drivers for N2O and utilize them to predict the spatial emission pattern of European organic soils. We conducted a meta-study with a total amount of 659 annual N2O measurements, which was…

Improvement in yield and fruit size and quality of the main Italian table olive cultivar 'Nocellara del Belice'

2014

Olive (Olea europaea L.) shows alternate bearing, with unreliable cropping patterns and inconsistent fruit size and quality every year. In many countries, thinning with naphthaleneacetic acid (NAA) is used to minimise alternate bearing behavior in olives. However, in Italy, growers are reluctant to employ this practice and no detailed knowledge is available for specific cultivars. We evaluated the effects of spraying NAA on various dates on the productive and vegetative characteristics of the main Italian table olive cultivar'Nocellara del Belice'. Trunk cross-sectional area, fruit set, fruit drop, fruit size, pit size, yield per tree, crop density and flesh to pit ratio were analysed. The …

Plutselig er alt på plass! : Verdiløse menn - misantropisk brødrebånd i det borgerlige parnass

2018

Masteroppgave nordisk språk og litteratur NO500 - Universitetet i Agder 2018

The role of landscape, topography, and geodiversity in explaining vascular plant species richness in a fragmented landscape

2016

We explained vascular plant species richness patterns in a 286 km(2) fragmented landscape with a notable human influence. The objective of this study was two-fold: to test the relative importance of landscape, topography and geodiversity measures, and to compare three different landscape-type variables in species richness modeling. Moreover, we tested if results differ when only native species are considered. We used generalized linear modeling based variation partitioning and generalized additive models with different explanatory variable sets. Landscape and topography explained the majority of the variation but the relative importance of topography and geodiversity was higher in explainin…

Villancicos, que se han de cantar en los solemnes Maytines del Nacimiento de Nuestro Señor Jesu-Christo en la Santa Iglesia Metropolitana de Valencia…

Grav. xil. de la Mare de Déu de la Seu amb el Jesuset Totes les p. orlades Sign.: [ ]4 Text a línia tirada i a dues col. separades per filet Reclams

Uptake from water, biotransformation, and biliary excretion of pharmaceuticals by rainbow trout.

2011

An urgent need exists to assess the exposure of fish to pharmaceuticals. The aim of the present study was to assess the uptake and metabolism of waterborne pharmaceuticals in rainbow trout (Oncorhynchus mykiss). A further objective was to determine the possibility of monitoring exposure to low levels of pharmaceuticals by bile assays. Rainbow trout were exposed for 10 d under flow-through conditions to mixtures of five pharmaceuticals (diclofenac, naproxen, ibuprofen, bisoprolol, and carbamazepine) at high and low concentrations. The low concentration was used to mimic the conditions prevailing in the vicinity of the discharge points of wastewater treatment plants. The uptake and the biocon…

Managing a boreal forest landscape for providing timber, storing and sequestering carbon

2015

Human well-being highly depends on ecosystem services and this dependence is expected to increase in the future with increasing population and economic growth. Studies that investigate trade-offs between ecosystem services are urgently needed for informing policy-makers. We examine the trade-offs between a provisioning (revenues from timber selling) and regulating (carbon storage and sequestration) ecosystem services among seven alternative forest management regimes in a large boreal forest production landscape. First, we estimate the potential of the landscape to produce harvest revenues and store/sequester carbon across a 50-year time period. Then, we identify conflicts between harvest re…

Tractats, etc. Alemanya, 1725

Sig. A-F4, G2 Port. orlada amb escut reial xil. - Reclams. - Vinyeta i capital grav. al començament del text