Search results for "73"

COVID-19 Vaccination in Pregnancy, Paediatrics, Immunocompromised Patients, and Persons with History of Allergy or Prior SARS-CoV-2 Infection: Overvi…

2021

To date, four vaccines have been authorised for emergency use and under conditional approval by the European Medicines Agency to prevent COVID-19: Comirnaty, COVID-19 Vaccine Janssen, Spikevax (previously COVID-19 Vaccine Moderna) and Vaxzevria (previously COVID-19 Vaccine AstraZeneca). Although the benefit–risk profile of these vaccines was proven to be largely favourable in the general population, evidence in special cohorts initially excluded from the pivotal trials, such as pregnant and breastfeeding women, children/adolescents, immunocompromised people and persons with a history of allergy or previous SARS-CoV-2 infection, is still limited. In this narrative review, we critically overv…

Notes on the Use of the Tables of Standard ISO 7730 for the Evaluation of the PMV Index

1996

Standard ISO 7730, which is also known as European Standard EN-ISO 7730, provides two alternative methods for the evaluation of the predicted mean vote (PMV) index: a calculation program and a set of tables. In order to use the tables, the operative temperature must be calculated beforehand. The impres sion is given from reading the standard that for a relative humidity of 50%, the two methods are equivalent, i.e. provide the same value for PMV, from the same initial values. In this paper, examples are given showing that the two methods are not equivalent. Differences between them are analysed and a proposal made to introduce an amendment in the next revision of the stan dard.

Faldaprevir (BI 201335), BI 207127 and ribavirin oral therapy for treatment-naive HCV genotype 1: SOUND-C1 final results

2013

Background Faldaprevir (BI 201335) and deleobuvir (BI 207127) are direct-acting antiviral agents under development for the treatment of chronic HCV infection. This article describes the final results of the Phase Ib SOUND-C1 study that evaluated the interferon-free oral combination of faldaprevir, deleobuvir and ribavirin in 32 treatment-naive patients infected with HCV genotype 1. Methods Patients were randomized to receive deleobuvir 400 mg ( n=15) or 600 mg ( n=17) three times daily plus faldaprevir 120 mg once daily and weight-based ribavirin for 4 weeks. Interferon-free therapy was followed by response-guided faldaprevir plus pegylated interferon-α2a/ribavirin to week 24 or 48. Results…

The relationship between animal cruelty in children and adolescent and interpersonal violence: A systematic review

2019

Abstract The following study is a systematic review of the relationship between animal cruelty and interpersonal violence. The systematic literature review following PRISMA guidelines and combined with the application of inclusion and exclusion criteria, enabled us to locate 32 studies published between 1995 and July 2017. Overall, the results show that episodes of animal cruelty during childhood and adolescence tend to co-occur alongside other forms of violent and antisocial behaviors. Cruelty to animals was associated with bullying, behavioral problems, experiences of abuse (emotional, physical and sexual), and juvenile delinquency. Furthermore, recurrent animal cruelty during childhood a…

Sánchez-Montes González, Francisco, Jiménez Estrella, Antonio, Lozano Navarro, Julián J. (editores). El Reino de Granada y la Monarquía Hispánica en …

2021

Señor. El Cabildo de la Santa Iglesia Metropolitana de la Ciudad de Lima, en Sede-vacante ... dice: Que por el Testimonio de Autos remitido à V. Ma…

1731

Com a tít. el començament del text Caplletres ornades Sign.: A4 Reclams

Pragmatica del tiempo, en defensa de la buena astrologia, contra el Juizio final de la astrologia, que escriviò el Doctor Don Martin Martinez / Su a…

1727

Sig. A4 Port. orlada, amb Cristus i filets. - Capital grav. al començament del text

Nouae coelestium orbium theoricae congruentes cum obseruationibus N. Copernici / Auctore Io. Antonio Magino ...

1589

Sig. A-Ff4 Els grav. xil. - Port. arquitextònica grav. - Frisos. - Capitals grav. Text amb postil·les marginals. - Reclams

The role of Kelvin-Helmholtz instability in the internal structure of relativistic outflows. The case of the jet in 3C 273

2006

Relativistic outflows represent one of the best-suited tools to probe the physics of AGN. Numerical modelling of internal structure of the relativistic outflows on parsec scales provides important clues about the conditions and dynamics of the material in the immediate vicinity of the central black holes in AGN. We investigate possible causes of the structural patterns and regularities observed in the parsec-scale jet of the well-known quasar 3C 273. We present here the results from a 3D relativistic hydrodynamics numerical simulation based on the parameters given for the jet by Lobanov & Zensus (2001), and one in which the effects of jet precession and the injection of discrete compone…

RadioAstron reveals a spine-sheath jet structure in 3C 273

2021

We present Space-VLBI RadioAstron observations at 1.6 GHz and 4.8 GHz of the flat spectrum radio quasar 3C 273, with detections on baselines up to 4.5 and 3.3 Earth Diameters, respectively. Achieving the best angular resolution at 1.6 GHz to date, we have imaged limb-brightening in the jet, not previously detected in this source. In contrast, at 4.8 GHz, we detected emission from a central stream of plasma, with a spatial distribution complementary to the limb-brightened emission, indicating an origin in the spine of the jet. While a stratification across the jet width in the flow density, internal energy, magnetic field, or bulk flow velocity are usually invoked to explain the limb-brighte…